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NCT ID: NCT05712590 Completed - Body Composition Clinical Trials

The Influence of the Nutritional Status of Women Between 30 and 45 Years of Age on the Condition of the Skin and Body Composition

VEGOMNI
Start date: December 19, 2022
Phase:
Study type: Observational

Goal is to investigate the differences in skin condition and body composition among women with different dietary habits aged 30-45 years. Study will be focused onto sub-groups of female subjects following omnivorous, vegetarian or vegan diet.

NCT ID: NCT05709015 Completed - Gingivitis Clinical Trials

Plaque Inhibitory Effect of Neutral Electrolysed Water in the Form of a Mouthwash in a 4-day Non-brushing Model

Start date: January 5, 2023
Phase: Phase 2
Study type: Interventional

Electrolysed water (EOW) is produced by the electrolysis of sodium chloride in an aqueous solution, producing chlorine gas at the anode and sodium hydroxide and hydrogen at the cathode. EOW is known to have antimicrobial effects against various microorganisms, including viruses, bacteria, spores and fungi. Its antimicrobial activity is generally attributed to its hypochloric acid content - a product of chlorine gas dissolved in water. Due to its biocompatibility, known uses of EOW include ocular disinfection, nasal irrigation and chronic cutaneous wound care. In the dental setting, it may be used as a mouthwash, disinfectant, irrigant, mouthwash or dental gel. The aim of this study is to investigate the effect of a mouthwash containing neutral electrolyzed water on plaque accumulation (evaluated using a disclosing agent and an intraoral scanner), gingival inflammation, MMP-8 activity and the oral microbiome. In this double-blind, cross-over, 4-day experimental gingivitis model, each subject will participate in all three arms of the study. Each arm will last 4 days, during which the subjects will be asked to refrain from toothbrushing and the use of interdental cleaning devices. Instead, they will be instructed to rinse their oral cavities twice daily with either EOW, placebo or a positive control (chlorhexidine), according to a randomisation chart (each subject will receive a different mouthwash type in every arm of the study). The outcomes will be assessed at baseline and after 4 days. A washout period of at least 7 days will be implemented between each study arm.

NCT ID: NCT05683925 Completed - Parkinson Disease Clinical Trials

Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Gait Characteristics in Parkinson's Disease

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

In this randomised placebo-controlled trial, the investigators will include 30 PD (Parkinson's disease) patients with HY (Hoehn Yahr stage) >2 and L-dopa unresponsive gait characteristics. Each participant will receive taVNS at 25Hz, taVNS at 100Hz and sham VNS (sVNS). During each stimulation, different gait characteristics will be measured with wearable insertion motion sensors.

NCT ID: NCT05661006 Completed - Clinical trials for Vitamin d Deficiency

ETOL-Elderly Study of the Efficiency of the Innovative Food Supplement in Elderly Adults

ETOL-Elderly
Start date: February 20, 2020
Phase: N/A
Study type: Interventional

The aim of this pilot study is to conduct a study on geriatric population in Slovenia (non-users of dietary supplements/medicines with vitamine D, vitamin B12 and protein) and assess deficiency of selected nutrients, and to investigate the efficiency of the innovative food supplement prototype in improving nutritional status of elderly adults.

NCT ID: NCT05627518 Completed - Pharmacokinetics Clinical Trials

Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation

BA
Start date: November 15, 2022
Phase: Phase 1
Study type: Interventional

This is a single-center, open-label, randomized, single dose, 3-way crossover study in healthy volunteers designed to evaluate the relative bioavailability of a new oral tablet formulation of linaprazan glurate in comparison to a previously studied oral tablet formulation under fasting conditions, and to assess the effect of a high fat, high calorie meal on the pharmacokinetics (PK) of linaprazan glurate and the active substance linaprazan after the administration of the new oral tablet formulation.

NCT ID: NCT05597605 Completed - Clinical trials for Diabetes Mellitus, Type 2

The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects

Start date: September 21, 2022
Phase: N/A
Study type: Interventional

The objectives of SHINE study are to confirm the safety aspects of the SHINE SYSTEM. Moreover, the goal of this clinical investigation is the initial evaluation of sensor's performance by assessing sensor's ability to qualitatively detect the appropriate analytes in subjects with diabetes of 18 years and older.

NCT ID: NCT05567926 Completed - Healthy Adults Clinical Trials

Acute Effects of Beetroot Juice on Isometric Knee Extension Strength, Explosive Strength and Local Muscular Endurance

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

This is a double-blind placebo-controlled cross-over trial that aims to determine the acute effect of beetroot juice ingestion on isometric knee extension strength, explosive strength and local muscular endurance.

NCT ID: NCT05524636 Completed - Healthy Clinical Trials

Effects of Peripheral Magnetic Stimulation

Start date: July 15, 2022
Phase: N/A
Study type: Interventional

Interventional study of the effectiveness of peripheral magnetic stimulation of the abdominal wall muscles in healthy individuals.

NCT ID: NCT05521893 Completed - Clinical trials for Gestational Diabetes

Effectiveness of Telemedicine Care Replacing Standard Care in Gestational Diabetes

Start date: March 12, 2020
Phase: N/A
Study type: Interventional

This is a a single-centre, parallel, randomized controlled trial in women with gestational diabetes mellitus (GDM). Women are randomized to routine monthly prenatal clinic care (standard care group) or a group sending daily glucose readings via an application installed on a smartphone and monthly individual videoconferences replacing in-person visits (telemedicine group). The overall aim is to compare the effectiveness of the combine synchronous and asynchronous telemedicine care with the standard care in women with GDM.

NCT ID: NCT05511896 Completed - Clinical trials for Occupational Exposure

Effects of a 60-min Repeated Trunk Flexion Protocol on Trunk Neuromuscular Properties.

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

An interventional study on the effects of repeated trunk flexion exposure on trunk neuromuscular properties.