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NCT ID: NCT04674592 Recruiting - Tibia Fracture Clinical Trials

Biomarkers in the Diagnosis of Acute Compartment Syndrome

BioFACTS
Start date: April 5, 2018
Phase:
Study type: Observational

This prospective multinational, multicentre cohort study aims to investigate the hypothesis that biomarkers of muscle cell damage can predict acute compartment syndrome in patients with tibial fractures.

NCT ID: NCT04674111 Completed - Clinical trials for Coronary Artery Disease

Vortex - Temporary Percutaneous, Transvalvular Circulatory Support System Feasibility Study

Vortex-FIH
Start date: September 28, 2021
Phase: N/A
Study type: Interventional

Vortex - First in Human study to evaluate the feasibility, safety, clinical and technical success of the Vortex temporary percutaneous, transvalvular circulatory support system (Vortex System)

NCT ID: NCT04673773 Recruiting - Low Back Pain Clinical Trials

MY RELIEF- Evidence Based Information to Support People Aged 55+ Years Living and Working With Persistent Low-back Pain.

MY-RELIEF
Start date: September 27, 2021
Phase: N/A
Study type: Interventional

Low back pain is the main cause of activity limitation and work absence across the world, leading to a high social and economic burden for individuals, families, the labour market and society. This is particularly true for older adults of working age, employed in sedentary or arduous/strenuous jobs, whose work conditions may influence negatively this health problem and lead to severe persistent low back pain. Pain management is one of the most neglected aspects of healthcare and people suffering from persistent low back pain are often left without specific information, guidance and care from healthcare systems. The MY-RELEF study is a multinational, multicenter, prospective uncontrolled, pre-post intervention feasibility study targeting people over the age of 55 years with persistent low back pain in Northern Lithuania, Ireland, Italy, Sweden and Portugal. Eligible participants will be offered the opportunity to use the MY RELIEF educational platform as part of their care and will undergo evaluations at baseline (enrollment) and at two-weeks and one-month follow-ups.

NCT ID: NCT04672850 Enrolling by invitation - Common Cold Clinical Trials

The Effect of Probiotic and Zinc Supplementation on the Common Cold

Start date: January 27, 2021
Phase: N/A
Study type: Interventional

The purpose with this study is to investigate the preventative effect of a supplement containing a combination of probiotic bacteria and fungi as well as zinc on the common cold. The hypothesis is that it will shorten the duration, alleviate the severity of symptoms or even decrease the number of infectons during the intervention period. This study is a randomzed placebo controlled human study were healthy adults will consume the supplement for three months.

NCT ID: NCT04670900 Recruiting - Olecranon Fracture Clinical Trials

Treatment of Olecranon Fractures in the Elderly

CROFT2
Start date: March 22, 2021
Phase: N/A
Study type: Interventional

Operative treatment, with tension band wiring or plate fixation, will be compared with non-operative treatment of displaced olecranon fractures (Mayo classification 2A and 2B) in patients 75 years or older.

NCT ID: NCT04670185 Completed - Parenting Clinical Trials

Internet-based Parent Training for Parents of Children With Externalising Behavior Problems

BIP-SAMBA
Start date: December 15, 2020
Phase: N/A
Study type: Interventional

The study aims to evaluate the efficacy of a 5-week, therapist-guided, internet-delivered parent management training program (BIP SAMBA) targeting children aged 5 - 11 years with externalising behavior problems. The study is a randomised controlled trial with parents of N=30 children participating. The intervention BIP SAMBA is compared with a waitlist control condition. Participants in the control condition will be crossed over to the active treatment after 5 weeks. The primary outcome measure is the Eyberg Child Behavior Inventory (ECBI) at the post treatment (5 weeks after baseline assessment).

NCT ID: NCT04669366 Completed - Kidney Neoplasms Clinical Trials

Treatment Patterns With Targeted Therapies In Mrcc In Sweden - A Retrospective Analysis Of Data From National Registries

Start date: January 20, 2021
Phase:
Study type: Observational

The objectives of this study is to investigate treatment patterns and outcomes for Sutent and Inlyta in mRCC patients in a nationwide population-based setting in Sweden.

NCT ID: NCT04668924 Active, not recruiting - Keratoconus Clinical Trials

Epi-on PiXL for the Treatment of Progressive Keratoconus.

Start date: March 20, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety and postoperative ocular discomfort by individually customized Photorefractive intrastromal crosslinking (PiXL) without epithelium debridement in high oxygen environment (Epi-on) for progressive Keratoconus.

NCT ID: NCT04667455 Active, not recruiting - Clinical trials for Cardiovascular Diseases

Improving Care for Children With Congenital Heart Disease.

Start date: February 17, 2020
Phase: N/A
Study type: Interventional

Establish a cardiovascular biomarker profile to help screening for congenital heart disease in infants and children as well as use non-invasive cardiac imaging in combination with such profiling to better predict the need for future cardiac interventions such as open heart surgery or cardiac catheter intervention selected types of with congenital heart disease.

NCT ID: NCT04667377 Completed - Obesity Clinical Trials

A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight

Start date: March 8, 2021
Phase: Phase 2
Study type: Interventional

This study is open to adults, aged 18 to 75 years, with overweight or obesity. People with body mass index (BMI) of 27 or higher to join the study. People who have diabetes cannot participate. The purpose of this study is to find out whether a medicine called BI 456906 helps people lose weight. Participants are put into 5 groups by chance. 4 groups get different doses of BI 456906. The fifth group gets placebo. Participants get BI 456906 or placebo as injections under the skin once a week. Placebo injections look like BI 456906 injections but do not contain any medicine. Participants are in the study for about a year. During this time, there are about 20 in-person visits to the study site. At the study site visits, doctors measure participants' body weight. Results are compared between the BI 456906 groups and the placebo group. The doctors also regularly check the general health of the participants.