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NCT ID: NCT05704608 Completed - Liver Functions Clinical Trials

Effects of Aerobic Training Program On Liver Functions

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The liver plays a central role in energy exchange, protein synthesis as well as the elimination of waste products from the body. The optimal functioning of the liver is essential for athletic performance. It becomes necessary to maintain the enzymes of the liver at an optimal level so that liver cells can be protected from inflammation or damage. This paper investigated the effects of a twelve-week aerobic exercise program on the liver function of adult athletes. A total of thirty (30) healthy male athletes aged 21 to 24 were recruited for this study and kept in two equal groups. The control group was kept under rigorous supervision and did not participate in any special activities. The experiment group was well-versed in their assigned training program and solely performed the experimental procedure for twelve (12) weeks. Evaluation of all patients in both experimental and control groups was carried out before and after the treatment program by measuring the levels of (Alkaline phosphate, AST/SGOT, ALT/SGPT, Bilirubin Total/indirect/direct, Albumin, Globulin, and Total protein) respectively using standard methods by collecting blood samples, 5 mls each of baseline into lithium heparin containers for estimation of above biochemical parameters at the pathology laboratory accredited by National Accreditation Board for Testing and Calibration Laboratories accredited (NABL, India).

NCT ID: NCT05699733 Not yet recruiting - Knee Arthritis Clinical Trials

Mechanical Traction Force and Knee Joint Space

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

the purposes of this crossover study are to Purpose 1. To determine the most effective traction force for knee joint that can be used in the treatment of patients with KOA. 2. To determine the influence of knee joint traction on ROM ok knee joint flexion and extension 3. To determine the influence of knee joint traction on the flexibility of hamstring muscles

NCT ID: NCT05698797 Completed - Clinical trials for Patellofemoral Pain Syndrome

Proprioceptive Training vs. Hip Abductor With External Rotator Strengthening in Patients With Patellofemoral Pain

Start date: November 11, 2021
Phase: N/A
Study type: Interventional

Patellofemoral pain syndrome (PFPS) is a common musculoskeletal disorder characterized by an insidious onset of pain in the knee's anterior /retro-patellar / peripatellar region. Even though various rehabilitation approaches, including hip strengthening and proprioceptive training, are being considered for managing PFPS, the most appropriate treatment from these two is still unclear. Therefore, this study aimed to compare the program consisting of hip abductors and external rotators strengthening exercises vs. the program consisting of proprioceptive training of the knee to identify the most effective rehabilitation approach for patients suffering from PFPS.

NCT ID: NCT05697991 Recruiting - Clinical trials for Type 2 Diabetes Mellitus

Non-Alcoholic Fatty Liver Disease in a Saudi Cohort With Type 2 Diabetes Mellitus

CORDIAL
Start date: March 23, 2015
Phase:
Study type: Observational [Patient Registry]

The global rise in the prevalence of obesity paved the way for the increased prevalence of yet another obesity-related complication significant enough to be considered within the roster of major public health threats: non-alcoholic fatty liver disease (NAFLD). In this follow-up study, the investigators will attempt to decipher the natural history of hepatic steatosis among patients with type 2 diabetes mellitus (T2DM) using state-of-the-art methods in a well-characterized Saudi cohort. The investigators aim also to validate existing biomarkers of disease severity and explore the pathogenesis of progressive disease using metabolic profiling technologies. A total of 1000 adult Saudi patients (males and females) with T2DM will be recruited. Those with co-morbidities, including hepatic decompensation, will be excluded. Participants will be followed three times for a total of 10 years/patient (Year 2, Year 5, and Year 10), and measures such as dietary evaluations, anthropometrics, and urine, stool, and blood examinations will be performed. Patients who develop NAFLD will be noted, and patterns/changes in the metabolic profile will be examined. For this specific grant (the first 2 years of the whole project), the investigators will be able to recruit the study cohort, do the baseline anthropometric, imaging, and biochemical measurements, and report the prevalence of NAFLD among patients with T2DM. This information will be the basis of subsequent follow-up and allow for validating potential diagnostic and prognostic biomarkers. This project will be of high importance at the national level since it will create awareness in the local medical community of the current severity status of NAFLD in the kingdom and will be used as a tool to promote public health awareness in the community.

NCT ID: NCT05692765 Completed - Clinical trials for Fruit and Vegetable Intake

Effects of a Smartphone Application on Fruit and Vegetable Consumption Among Saudi Adolescents

F&V intake
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Background: Dietary patterns and nutritional status during adolescence have a direct effect on future health outcomes. Objective: This study aimed to promote fruit and vegetable intake among adolescents using a smartphone application called "MyPlate." Methods: This randomized intervention study was conducted in an urban area of Jeddah, Saudi Arabia. The sample included 104 adolescents aged 13-18 years, who were randomized into intervention (n=55) or control (n=49) arms. The effects of a smartphone application ("My Plate") on fruit and vegetable intake was examined over 6 weeks in the intervention group. Pre- and postintervention questionnaires were used in the intervention and control groups.

NCT ID: NCT05692557 Completed - Clinical trials for Acute Respiratory Distress Syndrome

Virtual Reality Distraction Technique to Improve Chest Burns With Acute Respiratory Distress Syndrome

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Inhalation of toxic gases and chemical irritants during the fire leads to damage to the respiratory tract or the alveolar tissue, which is known as smoke inhalation injury. Acute Respiratory Distress Syndrome (ARDS) is associated with smoke inhalation injury. These patients usually need physiotherapy in the form of chest mobilization and breathing exercises for up to 4 to 6 weeks after discharge from the burns care centre. The patients during this phase are usually in pain and extremely anxious about these exercises. Virtual reality distraction (VRD) is one such technique that is gaining immense popularity recently, it has more immersive distraction when compared to traditional distraction techniques. This study aims to investigate the effect of a virtual reality distraction (VRD) technique as a pain alleviation tool for reducing pain during physiotherapy in burns patients with acute respiratory distress syndrome (ARDS) in a hospital setting.

NCT ID: NCT05692232 Completed - Clinical trials for Cervicogenic Headache

The Efficacy of Manual Therapy and Pressure Biofeedback Guided Strength Training on Pain and Functional Limitations

Start date: February 20, 2022
Phase: N/A
Study type: Interventional

Cervicogenic headache (CGH) is a widespread illness that results in excruciating pain and a sizable functional handicap. Deep cervical flexor muscle (DCFM) strength and endurance were also worse in CGH patients. This study aimed to determine the efficacy of manual therapy and pressure biofeedback-guided DCFM strength training on pain intensity and functional limitations in individuals with CGH.

NCT ID: NCT05691387 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease Exacerbation

Comparison of Active Cycle of Breathing Technique and Pursed Lip Breathing With TheraPep

Start date: December 30, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the short-term effects of two different breathing techniques (the active cycle breathing technique (ACBT) and the pursed lip breathing technique (PLB)) with Thera PEP® on the clearance of secretions and the oxygen saturation of individuals who have recently experienced an acute exacerbation of chronic obstructive pulmonary disease (COPD) in individuals who have recently experienced an acute exacerbation of COPD (COPD). Thirty patients will each have an acute COPD exacerbation seen on them, and then they will be randomly allocated to one of two groups (1. ACBT and PLB; 2. Thera PEP). Participants in a study employing a design known as a within-subject randomized crossover will be given the instruction to carry out each procedure on consecutive days as part of the study. In this study, the dependent variables will include blood pressure, heart rate, oxygen saturation (SpO2), respiratory rate, peak expiratory flow rate (PEFR), visual analog scale (VAS), sputum volume, and the breathlessness, cough, and sputum scale. In addition, the independent variables will include sputum volume (BCSC). The patient's desired course of treatment will also be taken into account. These dependent variables will be examined at three distinct moments in time: at the beginning of the study (the baseline), immediately after treatment, and thirty minutes after treatment has been completed.

NCT ID: NCT05684809 Recruiting - Clinical trials for Mechanical Neck Pain

Efficacy of Mobilization With Post- Isometric Relaxation in Neck Pain Associated With Myofascial Trigger Points

Start date: October 30, 2022
Phase: N/A
Study type: Interventional

purpose of the study: to determine the effectiveness of cervical mobilization with PIR in reducing pain and improving neck ROM and function in people with mechanical neck pain associated with MTrPs

NCT ID: NCT05684679 Completed - Clinical trials for Post Coronary Artery Bypass Grafting

Effectiveness of Incentive Spirometer and Diaphragmatic Breathing Exercise on ABG Measures in Post-CABG Patients

Start date: April 15, 2019
Phase: N/A
Study type: Interventional

The rate of pulmonary complications following Coronary artery bypass graft (CABG) is high. Early pulmonary exercises are important in preventing this complication following cardiac surgery. This study aimed to investigate the effectiveness of incentive spirometer (IS) and diaphragmatic breathing exercise (DBE) on the alteration of arterial blood gas (ABG) measures. The study was based on a two-arm, parallel-group, randomized comparative design. Thirty patients who underwent CABG enrolled in the study based on inclusion and exclusion criteria, randomly allocated into either of the groups, IS Group or DBE Group. IS Group and DBE Group underwent chest physiotherapy with IS and DBE, respectively. ABG measures, including PH of blood, partial pressure of arterial oxygen molecule (PaO2), and partial pressure of arterial carbon dioxide (PaCO2), was assessed using an ABG analyzer at baseline (pre-operation), day1 post-operation, and day2 post-operation. The significance level was kept constant for all statistical analyses at 95%.