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NCT ID: NCT03065010 Completed - Breast Cancer Clinical Trials

Study of BCD-115 in Women With ER(+) HER2(-) Local Advanced and Metastatic Breast Cancer

Start date: November 2016
Phase: Phase 1
Study type: Interventional

A Multicenter Open-label Non-comparative 2-Stage Phase 1a/1b Study to Assess the Safety and Pharmacokinetics of Oral BCD-115 (JSC BIOCAD, Russia) in Combination with Endocrine Therapy in Women with ER(+) HER2(-) Local Advanced and Metastatic Breast Cancer

NCT ID: NCT03062644 Completed - Acute Pain Clinical Trials

Efficacy and Safety in a Randomised Acute Pain Study of MR308: STARDOM2.

STARDOM2
Start date: April 5, 2017
Phase: Phase 3
Study type: Interventional

The MR308-3502 study is a multicenter double-blind, randomised, placebo- and active comparator-controlled study in female subjects to evaluate the efficacy and safety of MR308 with acute pain after TAH or STAH (total or subtotal abdominal hysterectomy).

NCT ID: NCT03061812 Completed - Clinical trials for Small Cell Lung Cancer

Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)

TAHOE
Start date: April 11, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this randomized, open-label, 2-arm, phase 3 study is to assess the efficacy, safety and tolerability of rovalpituzumab tesirine versus topotecan in participants with advanced or metastatic SCLC with high levels of DLL3, who have first disease progression during or following front-line platinum-based chemotherapy.

NCT ID: NCT03060317 Completed - Clinical trials for Consciousness Disorders

Validation of the Russian Version of Coma Recovery Scale-Revised (CRS-R)

Start date: November 1, 2016
Phase: N/A
Study type: Observational

The purpose of this study is to validate Russian version of Coma Recovery Scale - Revised and to assess its psychometric properties.

NCT ID: NCT03057418 Completed - Clinical trials for Lymphoma, Non-Hodgkin

Open-label Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Auriхim

Start date: June 2013
Phase: Phase 1
Study type: Interventional

This is an open-label study of safety, tolerability, pharmacokinetics and pharmacodynamics of Auriхim multiple doses in patients with recurrent/ refractory В-cell, CD20-positive non-Hodgkin lymphoma of low tumor grade or with follicular lymphoma, as well as in patients non-treated before for В-cell, CD20-positive non-Hodgkin lymphoma of low tumor grade. The study will be carried out in 4-6 Russian and Belarussian sites. The study will be consisted of screening period, induction (obligatory) phase and supporting (non-obligatory) phase of the investigational therapy and post-treatment follow-up period.

NCT ID: NCT03053180 Completed - Chronic Hepatitis C Clinical Trials

Real World Evidence of the Effectiveness of Paritaprevir/Ritonavir (r) - Ombitasvir, + Dasabuvir Without Ribavirin in Participants With Chronic Hepatitis C and Compensated Liver Cirrhosis in the Russian Federation

CITRIN
Start date: March 20, 2017
Phase:
Study type: Observational

This prospective, multi-center, observational study is designed to assess the real world effectiveness of paritaprevir/r - ombitasvir with dasabuvir (3DAA [direct-acting antiviral agent] ABBVIE REGIMEN) without ribavirin (RBV) and to describe baseline characteristics of participants with chronic hepatitis C virus (HCV) genotype 1b (GT1b) infection and compensated liver cirrhosis in Russia.

NCT ID: NCT03050489 Completed - Clinical trials for Coronary Artery Disease

Assessment of Myocardial Ischemic-Reperfusion Injury During Off- and On- Pump CABG

Start date: September 15, 2015
Phase:
Study type: Observational

Assessment of myocardial ischemic-reperfusion injury during off- and on- pump CABG.

NCT ID: NCT03044574 Completed - Clinical trials for Venous Thromboembolism

Intermittent Pneumatic Compression in Surgical Patients at Extremely-high Risk for Venous Thromboembolism

IPCSUPER
Start date: February 1, 2017
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate efficacy and safety of venous thromboembolism prophylaxis by the combination of graduated compression stockings (GCS), standard doses of low-molecular-weight heparins (LMWH) and sequential compression device (SCD) in the mixed group of surgical patients at high and extremely high risk for venous thromboembolism.

NCT ID: NCT03043690 Completed - Clinical trials for Menopause Related Conditions

A Pooled Analysis of the Data From Two Studies of Ammonium Succinate for Menopausal Symptoms

Start date: February 11, 2017
Phase: N/A
Study type: Observational

This study is a pooled statistical analysis of the data from 2 studies concerning efficacy of ammonium-succinate based dietary supplement. In both studies group 1 took the ammonium-succinate based dietary supplement and the group 2 took placebo.

NCT ID: NCT03042611 Completed - Gastric Cancer Clinical Trials

A Study to Evaluate Rivoceranib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Participants With Gastric Cancer

ANGEL
Start date: March 14, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of rivoceranib plus best supportive care (BSC) compared to placebo plus BSC in participants with advanced or metastatic gastric cancer (GC).