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NCT ID: NCT04951349 Completed - Covid19 Clinical Trials

Safety and Efficacy of Intranasal Application of GX-03 as a Treatment and Prevention for COVID-19.

Start date: January 21, 2021
Phase: Phase 2
Study type: Interventional

Phase 2b clinical trial to evaluate the safety and efficacy of intranasal application of GX-03 as a treatment and prevention for COVID-19.

NCT ID: NCT04847024 Completed - Clinical trials for Caesarean Section; Pain

Parecoxib vs. Dexketoprofen for the Management of Pain After Cesarean Section.

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Although it is known that parecoxib and dexketoprofen are commonly used in successful post-operative pain relief, there are very few studies that compare these two agents in their individual applications and/or combined with neuraxial analgesia with opioids and even less in post-cesarean section pain, as well as the evaluation of the side effects and their impact on the patient's functionality. For this reason, in order to approach this answer, we sought to perform this study in patients undergoing elective or emergency cesarean section in our institution, who meet the inclusion criteria, using the Visual Analog Pain Scale at 12 hrs and 24 hrs post surgery and evaluating the aforementioned side effects, comparing in one arm of the study Parecoxib + acetaminophen vs Dexketoprofen + acetaminophen in the other arm, randomizing the patients in both groups using a double-blind configuration.

NCT ID: NCT04841577 Completed - Clinical trials for Respiratory Syncytial Virus Infections

A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 60 Years and Above

Start date: April 27, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the immunogenicity, safety and reactogenicity of the RSVPreF3 OA investigational vaccine when co-administered with the seasonal quadrivalent influenza vaccine (FLU-QIV) in adults aged 60 years and above compared to separate administration of the vaccines.

NCT ID: NCT04814134 Completed - Clinical trials for Acute Decompensated Heart Failure

Cardionomic STOP-ADHF Study

Start date: April 12, 2021
Phase: N/A
Study type: Interventional

STOP-ADHF Study: An evaluation of the safety and performance of the Cardionomic Cardiac Pulmonary Nerve Stimulation (CPNS) system in patients with acute decompensated heart failure.

NCT ID: NCT04791020 Completed - Pain Clinical Trials

Topic Cervical Anesthesia Plus Paracervical Blockade for Pain Control During Endouterine Manual Aspiration

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

To compare the effectiveness of lidocaine gel plus paracervical blockade vs. lidocaine gel alone in the management of pain during endouterine manual aspiration.

NCT ID: NCT04652102 Completed - Covid19 Clinical Trials

A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older

Start date: December 11, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective of the randomized observer-blinded phase 2b/3 part of this trial is to demonstrate the efficacy of a 2-dose schedule of CVnCoV in the prevention of first episodes of virologically-confirmed cases of COVID-19 of any severity in SARS-CoV-2 naïve participants.

NCT ID: NCT04515147 Completed - Covid19 Clinical Trials

A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19

Start date: September 21, 2020
Phase: Phase 2
Study type: Interventional

This study aims to evaluate the safety and reactogenicity profile after 1 and 2 dose administrations of investigational SARS-CoV-2 mRNA vaccine (CVnCoV) at different dose levels and to evaluate the humoral immune response after 1 and 2 dose administrations of CVnCoV.

NCT ID: NCT04448132 Completed - Poliomyelitis Clinical Trials

Evaluation of Persistence of Immunity in 4-year-old Children Previously Immunised With IPV-Al AJV (Picovax®)

Start date: November 20, 2020
Phase: Phase 4
Study type: Interventional

The trial is a phase 4, open-label, multicentre clinical trial with healthy subjects who have been vaccinated with IPV-Al AJV at 2, 4, 6 and 15 18 months of age in previous trials. Levels of antibodies against poliovirus types 1, 2 and 3 after immunisation with IPV Al AJV will be measured in the trial subjects at the age of 4 years. An additional IPV-Al AJV dose (investigational vaccine) will be administered and the booster response to IPV-Al AJV will be investigated one month after administration.

NCT ID: NCT04330001 Completed - Presbyopia Clinical Trials

Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL

Start date: December 28, 2020
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to assess the repeatability of objective refraction using auto refraction on subjects bilaterally implanted (implanted in both eyes) with the Fluid Accommodating IOL (FAIOL).

NCT ID: NCT04126213 Completed - Clinical trials for Respiratory Syncytial Virus Infections

Study of Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline's (GSK)Respiratory Syncytial Virus (RSV)Maternal Unadjuvanted Vaccine in Healthy Pregnant Women (Aged 18 to 40 Years) and Their Infants

Start date: November 5, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study was to evaluate the safety and immune response to a single intramuscular (IM) dose of GSK Biologicals' investigational RSV maternal vaccine (RSVPreF3) in healthy pregnant women 18-40 years of age and in infants born to vaccinated mothers.