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NCT ID: NCT03523858 Recruiting - Clinical trials for Progressive Multiple Sclerosis (PMS)

A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis

CONSONANCE
Start date: May 28, 2018
Phase: Phase 3
Study type: Interventional

This study is a prospective, multicenter, open-label, single-arm effectiveness and safety study in participants with progressive multiple sclerosis (PMS).

NCT ID: NCT03489798 Not yet recruiting - Induction of Labor Clinical Trials

Comparison of Two Protocols of Misoprostol (PGE1) and the Rate of Cesarean Section Due to Failed Induction.

Start date: April 5, 2018
Phase: N/A
Study type: Interventional

To compare two protocols of misoprostol use for cervical ripening: 3 doses (25 ug vaginal each) or up to six doses, every six hours, until an adequate cervical condititon was achieved (BIshop score > 6). In the first group, after 3 doses, the patient was sent to the delivery room for induction with oxytocin and in case of failure, a cesarean section was indicated for this reason. In the second group, up to six doses were used in a similar fashion. Rates of success were evaluated, as well as maternal and fetal complications.

NCT ID: NCT03480906 Recruiting - Clinical trials for Intraocular Pressure

Eyenovia MiDD Usability Study

Start date: March 12, 2018
Phase: N/A
Study type: Interventional

This study is to evaluate the usability and patient tolerability for microtherapeutic dosing of commercially available ocular medication via the Eyenovia microdose delivery system (MiDD)

NCT ID: NCT03442218 Active, not recruiting - Endometritis Clinical Trials

Use of Antiseptic Solution for Vaginal Wash Before Cesarean Section

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

To evaluate the rate of infections after cesarean sections in patients with premature rupture of membranes after vaginal wash either with an antiseptic solution (clorhexidine solution) vs. saline solution (placebo).

NCT ID: NCT03441217 Not yet recruiting - Labor Clinical Trials

Hyoscine Butylbromide Effect on Duration of Labor

Start date: February 19, 2018
Phase: N/A
Study type: Interventional

To evaluate the duration of labour (active phase of labour) in nulliparous women with gestations between 37 and 41 6/7 weeks when 20 mg of Hyoscine butylbromide was applied intravenously and compared with similar patients that received a placebo.

NCT ID: NCT03423979 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

Optilumeā„¢ BPH Prostatic Drug Coated Balloon Dilation Catheter

EVEREST-I
Start date: December 19, 2017
Phase: Phase 2
Study type: Interventional

A prospective, non-randomized, feasibility study. The subjects will be enrolled and treated with the Optilume BPH Prostatic DCB Dilation Catheter System at up to 15 clinical sites. The post-treatment follow-up visit can be up to 5 years. The objective of the study is to evaluate the safety and performance of the Optilumeā„¢ BPH Prostatic Drug Coated Balloon Dilation Catheter System in the treatment of BPH.

NCT ID: NCT03397082 Completed - Pain Clinical Trials

Topic Cervical Anesthesia for Pain Control During Endouterine Manual Aspiration

Start date: August 1, 2014
Phase: N/A
Study type: Interventional

To compare the effectiveness of lidocaine gel plus paracervical blockade vs. Paracervical blockade alone in the management of pain during endouterine manual aspiration.

NCT ID: NCT03374553 Recruiting - Open Angle Glaucoma Clinical Trials

MINIject 636 in Patients With Open Angle Glaucoma Uncontrolled by Topical Hypotensive Medications

Start date: November 25, 2017
Phase: N/A
Study type: Interventional

The study will evaluate the efficacy and safety of MINIject 636 and IOP lowering effects with or without glaucoma medications. The procedure will be a stand-alone surgery. Overall, the patient will be asked to perform several examinations up to 24 months after surgery. The primary efficacy objective of the present study is to show the IOP reduction under medication 6 months after surgery compared to medicated diurnal IOP at screening.

NCT ID: NCT03371017 Recruiting - Clinical trials for Triple Negative Breast Neoplasms

A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Cancer

IMpassion132
Start date: January 31, 2018
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of atezolizumab plus chemotherapy compared with placebo plus chemotherapy in patients with inoperable recurrent triple-negative breast cancer (TNBC).

NCT ID: NCT03360240 Completed - Clinical trials for Adolescent Pregnancy

Blood Pressure in Adolescents With PReclampsia and Eclampsia.

ADPRE
Start date: August 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

Levels of blood pressure in adolescents with preeclampsia and eclampsia: Multicenter case-control study (Latin America). Maternities in Latin America: Two hospitals in Panama, one hospital in Mexico, one hospital in El Salvador, one hospital in Guatemala, two hospitals in Honduras, one hospital in Colombia, two hospitals in Peru and two hospitals in Bolivia. The objective is to evaluate the basal levels of blood pressure during pregnancy and determine if there is any increase that is associated with the development of preeclampsia and eclampsia without reaching the known values of 140/90 mm Hg. The sample is 718: (240 Cases and 478 Controls).