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NCT ID: NCT05406297 Recruiting - Clinical trials for STEMI - ST Elevation Myocardial Infarction

Impact of TMAO Serum Levels on Hyperemic IMR in STEMI Patients

Start date: January 12, 2021
Study type: Observational

Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite of dietary choline, L-carnitine, and phosphatidylcholine-rich foods. On the basis of experimental studies and patients with prevalent disease, elevated plasma TMAO may increase risk of atherosclerotic cardiovascular disease (ASCVD). However, to our knowledge, no data is available on its impact on coronary microcirculation.

NCT ID: NCT05396547 Not yet recruiting - Cataract in Old Age Clinical Trials

Study On The Performance And Safety Of The LEDINBIO CE Device On Visual Acuity In Subjects With Cataract

Start date: June 2022
Phase: N/A
Study type: Interventional

Single arm, unmasked study to evaluate the performance and safety of the LEDINBIO CE Device for the non-invasive treatment of vision loss in age-related cataract.

NCT ID: NCT05378919 Recruiting - Clinical trials for Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX

Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer

Start date: June 1, 2015
Phase: Phase 2
Study type: Interventional

Phase II, Multicenter, Open-label, Randomized Study evaluating neoadjuvant chemotherapy (FOLFOX4) in patients with stage II and III colorectal cancer with standard chemoradiation Defined by Magnetic Resonance Imaging

NCT ID: NCT05378529 Recruiting - Clinical trials for Atherosclerotic Cardiovascular Disease

A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD)

Start date: April 19, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to characterize the distribution of lipoprotein(a) (Lp(a)) levels among participants with a history of ASCVD as defined by their medical history and is 2-fold: - Evaluate the distribution of Lp(a) value in the overall participants with documented history of ASCVD - Evaluate the distribution of Lp(a) value in participants with documented history of ASCVD by demographics and regions

NCT ID: NCT05354323 Recruiting - Solid Tumors, Adult Clinical Trials

NECVAX-NEO1 in Addition to Checkpoint Inhibitor in Patients With Solid Tumors

Start date: May 5, 2022
Phase: Phase 1
Study type: Interventional

NECVAX-NEO1 in addition to anti-PD-1 or anti-PD-L1 monoclonal antibody checkpoint inhibitor monotherapy in n=6 patients with solid tumors

NCT ID: NCT05353686 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes

Start date: February 25, 2019
Phase: Phase 2
Study type: Interventional

This is a randomised, double-blind, placebo-controlled, parallel-group trial investigating the effect of 4 weeks bi-daily dosing of XEN-D0501 on blood glucose reduction as add-on to metformin in patients with diabetes mellitus type 2 where life style changes and treatment with metformin has failed to effectively reduce blood glucose concentrations.

NCT ID: NCT05343195 Completed - Hip Injuries Clinical Trials

Balance and Leg Function After Hip Replacement

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

Task-oriented leg exercise are commonly used after joint surgeries in various hip pathologies. Based on this theory, it was hypothesized that task-oriented exercise without conventional physiotherapy can have better result in recovery of balance and leg function than with a conventional post-hip physiotherapy program after hip replacement surgery. The aim of the study was to determine the effect of task-oriented exercise on balance and leg function after total hip replacement.

NCT ID: NCT05325658 Enrolling by invitation - Clinical trials for Oropharyngeal Dysphagia

Influence of Modified Diet, Exercise and Electrical Swallowing Muscle Stimulation on Swallowing Function and Quality of Life in Elderly Patients With Oropharyngeal Dysphagia

Start date: May 21, 2021
Study type: Observational

Tasks of biomedical research: 1. To determine the severity of oropharyngeal dysphagia and the risk of aspiration in elderly patients. 2. To evaluate the quality of life of older patients with oropharyngeal dysphagia by performing validation of the Lithuanian version of the quality of life questionnaires in patients with oropharyngeal dysphagia. 3. To evaluate the severity of oropharyngeal dysphagia in elderly patients, the risk of aspiration, and quality of life after interventions. Data on the sex, age and disease of the swallowing disorder will be collected. No processing of other personal data and health indicators is planned. All data will be collected in questionnaires. The data will be depersonalized by giving the patient a code. The results and conclusions of the research will be described in the doctoral dissertation and will be used for scientific articles.

NCT ID: NCT05320562 Completed - Osteoarthritis Clinical Trials

Effect of Kinesio Taping and Sham Taping in Knee Osteoarthritis

Start date: February 20, 2021
Phase: N/A
Study type: Interventional

The prevalence of knee osteoarthritis has been increasing in recent decades as the number of obese people has increased. Various interventions are used to improve the functional condition of patients, but it is still not clear which one is most effective. The primary aim of this study was to determine and compare the effects of kinesio taping and sham taping on the knee functional mobility.

NCT ID: NCT05287074 Enrolling by invitation - Clinical trials for Food Allergy in Children

The Significance of a Timely Food Allergy Diagnosis and Optimal Surveillance of Nutritional Status in Children

Start date: July 1, 2021
Study type: Observational

The aim of this study is to gain more knowledge on the nutritional and immunological aspects of allergy to milk and eggs in children.