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NCT ID: NCT04817995 Recruiting - Perceived Stress Clinical Trials

Stress Recovery Program FOREST for Healthcare Staff

FOREST
Start date: April 2021
Phase: N/A
Study type: Interventional

The aim of the study is to assess the efficacy of an internet-based stress recovery intervention among healthcare staff during COVID-19 pandemic.

NCT ID: NCT04810208 Recruiting - Solid Tumor Clinical Trials

Intratumoural Injection of a Novel NanoZolid®-Docetaxel Depot Formulation in Patients With Advanced Solid Tumours

Start date: February 28, 2019
Phase: Phase 1
Study type: Interventional

This is a multicentre, open-label, first in man, study of a novel NanoZolid®-docetaxel depot formulation (NZ-DTX Depot) given as an intra-tumoural injection in patients with advanced solid tumours. The study includes a dose escalation part and a dose expansion part.

NCT ID: NCT04784117 Recruiting - Clinical trials for Out-Of-Hospital Cardiac Arrest

Out-of-hospital Cardiac Arrest Epidemiology and Outcomes in Kaunas 2016-2021

Start date: January 1, 2016
Phase:
Study type: Observational

Out-of-hospital cardiac arrest rate is common problem, because of high mortality rate. It is not clear incidence rate, epidemiology and outcomes in Lithuania and Kaunas city included.

NCT ID: NCT04775758 Enrolling by invitation - Clinical trials for Persistent Idiopathic Facial Pain

Atypical Orofacial Pain Diagnostics and Differentiation.

Start date: February 27, 2021
Phase: N/A
Study type: Interventional

Orofacial pain is diagnosed for more than 1.9 percent of general population and for 0.3 percent origin of the facial pain is unknown. Commonly atypical facial pain is treated as a neurological condition without an emotional or psychiatric evaluation. Since atypical pain and mood affective disorders can be related, patients do not receive proper care for this condition. The aim of this study is to evaluate the relationship between atypical facial pain syndrome and affective mood disorders. We aim to assess patients' with no diagnosed organic pathology tendency towards anxiety, depression, sleep disorders and one of big five personality traits through self-rating questionnaires. We will compare the gathered data with biosensors from iMotions software.

NCT ID: NCT04773717 Completed - Sepsis Clinical Trials

The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of high-dose ascorbic acid on microcirculation in sepsis.

NCT ID: NCT04768283 Recruiting - Frailty Syndrome Clinical Trials

Cardiac Rehabilitation and Additional Physical Training in Elderly Patients After Acute Coronary Syndrome

Start date: January 6, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate functional and physical capacity, health-related quality of life and associations with frailty in older patients after ischemic heart disease and interventional treatment with an individualized physical training program in the second phase of cardiac rehabilitation.

NCT ID: NCT04763187 Completed - Embedded Tooth Clinical Trials

Post-extractive Alveolus Regeneration

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Healing of post-extraction alveolus is a complex process that involves soft and hard tissues regeneration. Pain, swelling, difficulty of opening the mouth, delayed healing of bone tissue, alveolitis and horizontal or vertical resorption of bone tissue are the main problems that have impact on consequent treatment. Blood concentrates PRGF (plasma rich in growth factors) and PRF (platelet-rich fibrin), which are rich in growth factors, create better conditions for post-extraction alveolus healing and enhance quality of soft tissues and bone regeneration. Our study objective was to compare physiological healing of post-extraction zone, PRF and PRGF induced changes of healing process. Methods that we used: 43 patients were randomly divided into 3 groups: I control group - lower molar extraction and filling of post-extraction alveolus with hemostatic sponge containing gentamicin, II group - post-extraction alveolus is filled PRGF and III group - post-extraction alveolus is filled with PRF. Bone regeneration was evaluated in CBCT scans after 1 month. Pain was evaluated using visual analogical scale (VAS).

NCT ID: NCT04760119 Recruiting - Clinical trials for Critical Limb Ischemia

Drug-Eluting Balloon Angioplasty Versus Bypass Surgery as First-Line Strategies in Infrageniculate Arterial Disease for Critical Limb Ischemia in Type 2 Diabetic Pacients: a Randomised Controlled Clinical Trial

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the outcomes of drug-eluting balloon angioplasty and vein bypass surgery in diabetic patients with critical limb ischemia due to infrapopliteal arterial disease.

NCT ID: NCT04737525 Active, not recruiting - Immediate Implants Clinical Trials

Connective Tissue Graft Versus a Porcine-derived Membrane (Mucoderm) After Immediate Placement

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Esthetic outcome of immediate implant placement in fresh extraction sockets remains one of the biggest challenges in implant dentistry. Recently a method to preserve the peri-implant tissues was introduced using provisional restoration, allogenic bone and soft tissue thickening. However, the evidence that this immediate provisialisation with soft tissue grafting using different grafting materials results in constantly high Pink Esthetic scores, especially compared to the delayed loading approach is still lacking. The aim of this clinical trial is to assess the esthetic outcome of immediate temporization of immediately placed and loaded tapered implants in fresh extraction sockets with bone and soft tissue augmentation, using either a connective tissue graft (CTG) or a porcine-derived membrane (Mucoderm) in maxillary anterior sites. The secondary objectives are to investigate the influence of immediate loading on the success rate of tapered implants and crestal bone levels.

NCT ID: NCT04736199 Recruiting - Prostatic Neoplasms Clinical Trials

Darolutamide in Addition to ADT Versus ADT in Metastatic Hormone-sensitive Prostate Cancer

ARANOTE
Start date: February 23, 2021
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy and safety of darolutamide in combination with standard androgen deprivation therapy (ADT) in patients with metastatic hormone sensitive prostate cancer.