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NCT ID: NCT05844410 Completed - COVID-19 Pandemic Clinical Trials

Evaluation of Corticosteroids Use and Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Study

Start date: October 20, 2021
Phase:
Study type: Observational

Despite the recommendations to avoid using corticosteroids systematically for hospitalized coronavirus disease of 2019 (COVID-19) patients, healthcare professionals used personalized treatments, including corticosteroids, as adjuncts to treat their patients due to their limited access to treatment options. This study aims to evaluate the use of corticosteroids among hospitalized COVID-19 patients with all-cause mortality as the primary outcome and to assess the predictors of all-cause mortality associated with the characteristics of the patients and the corticosteroid regimens adopted.

NCT ID: NCT05843565 Recruiting - Clinical trials for Intubation; Difficult or Failed

Standard Versus Hyperangulated Video Laryngoscopy Blades for Intubation in Neonates and Small Infants

Start date: June 14, 2023
Phase: N/A
Study type: Interventional

The goal of this prospective randomized cross over clinical trial is to compare the difference in the percentage of glottic opening (POGO) between two different video laryngoscopy blades, the hyperangulated Cobalt blade and the straight Miller blade in neonates or small infants with body weight ≤ 5 kg and age ≤ 3 months. The main questions it aims to answer are: - Is there a significant difference in the POGO using the standard Miller video laryngoscope blade versus the non-standard hyperangulated Cobalt video laryngoscope blade in neonates and small infants? - Are there significant differences in the first attempt success rate at intubation, the number of attempts, the time to successful intubation, the type of blade used for successful intubation, and the occurrence of adverse events during intubation, such as episodes of bradycardia or desaturation? 40 (20 in each group) neonates or small infants with body weight ≤ 5 kg or age ≤ 3 months will be enrolled in one of the two groups over 2 years of work. Researchers will compare the POGO and Cormack and Lehane (C&L) classification using the hyperangulated Cobalt blade versus the straight Miller blade to identify the technique that provides optimal glottic views and intubating conditions in this patient population, and thus improved patient's safety.

NCT ID: NCT05836129 Completed - Stress Clinical Trials

Lowering Stress Levels of Women in Lebanon

TML
Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the experiences of women who learn the TM technique to those who do not. The main questions it aims to answer are: 1. Do women in rural Lebanon who practice the TM technique experience lower stress levels compared to those who do not. 2. Do women in rural Lebanon who practice the TM technique experience increased happiness, self-efficacy, and resilience levels compared to those who do not. Participants will: - complete baseline surveys - be divided into experimental and active-control groups - those in the experimental group will learn the TM technique, the control group will be offered an online didactic course on stress reduction - both groups will complete post-test surveys at the end of 1 and 3 months - Researchers will compare experimental and control groups to see if the intervention effects stress levels.

NCT ID: NCT05813613 Completed - Fatigue Clinical Trials

Role of Artificial Intelligence in Predicting Muscle Fatigue Using Virtual Reality Training

Start date: April 15, 2023
Phase:
Study type: Observational

The goal of this observational predicted study is to predict muscle fatigue using a specific AI algorithm in healthy vs post Covid-19 infected individuals. The main question it aims to answer is: Can Artificial Intelligence be used as a reliable source of predicting localized muscle fatigue in healthy vs post Covid-19 infected individuals? Participants will be divided into two groups: A healthy group and a post Covid-19 group. - Each group will undergo a familiarization process before the start of the exercises. - Then, each group will perform squatting exercises guided by the kynpasis virtual reality apparatus. - sEMG for the vastus lateralis and rectus femories, chest expansion, and goniometric measurements of the knee will be taken during different reported fatigue levels using the Biopac system. - Groups will continue squatting while recording their subjective fatigue levels using the Borg scale. - Data will then be run through machine learning processes to produce an AI algorithm capable of predicting isolated muscle fatigue.

NCT ID: NCT05768243 Completed - Clinical trials for Periodontitis Chronic Generalized Severe

Hyaluronic Acid Versus Red Injectable Platelet Rich Fibrin in Treatment of Periodontitis

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

the aim of this clinical trial is to compare the efficacy of hyaluronic acid (HA) used as an adjunctive to scaling and root planing (SRP) and red injectable platelet rich-fibrin (i-PRF) in the non-surgical treatment of stage III periodontitis. The main question it aims to answer is: is there a difference between HA and red i-prf when used as an adjunct to SRP in terms of efficacy? Participants who are eligible will be assigned to one of the treatment groups: - Group 1= receives HA+ SRP - Group 2= receives red i-prf + SRP - Group 3= receives only SRP Researchers will compare Groups 1,2 and 3 to see if there's a difference in the periodontal parameters measured.

NCT ID: NCT05767034 Recruiting - Clinical trials for Polymyalgia Rheumatica

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)

REPLENISH
Start date: March 22, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the efficacy and safety of secukinumab 300 milligram (mg) and 150 mg administered subcutaneously (s.c.) for 52 weeks in combination with prednisone tapered over 24 weeks in adult participants with PMR who have recently relapsed.

NCT ID: NCT05761730 Recruiting - Clinical trials for Irreversible Pulpitis

Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy

Start date: February 15, 2023
Phase: Phase 1
Study type: Interventional

The efficacy of short course orally administered dexamethasone on the reduction of pain before conventional pulpotomy has not yet been demonstrated. Therefore, the aim of this randomized clinical study is to assess the effect of dexamethasone on the reduction of pain in mandibular molars with irreversible pulpitis, without performing conventional pulpotomy in comparison to pain following pulpotomy.

NCT ID: NCT05756010 Recruiting - Clinical trials for Temporomandibular Disorder

Effect of Forward Head Correction on EMG of Masticatory Muscles in Patients With TMD

Start date: June 7, 2023
Phase: N/A
Study type: Interventional

This study aims to investigate the effects of forward head correction exercises on EMG of masticatory and cervical muscles in patients with temporomandibular disorder. The study's design will be double-blinded, randomized controlled trial. Patients suffering from TMD will be included in the program. The participants will allocate to one of two groups at random: the experimental group will perform a program consisting of two strengthening exercises (deep cervical flexors and shoulder retractors) and two stretchings (cervical extensors and pectoral muscles) and the control group will receive only neck flexion exercise.. This exercise program will be repeated 4 times per week for 10 weeks, and each session lasted for 30 minutes. The muscle activity EMG of masseter, temporalis, splenius, upper trapezius, and SCM will be measured pre and post-assessment using a biopic data acquisition system.

NCT ID: NCT05729022 Not yet recruiting - Clinical trials for Radiculopathy Lumbar

Ultrasound-Guided Microendoscopic Versus Fluoroscopic-Guided Lumbar Transforaminal Epidural Steroid Injections

Start date: December 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the Microendoscopic combined with ultrasound technique to the standard routinely used X-ray guided transforaminal steroid injection technique.

NCT ID: NCT05693402 Completed - Surgery Clinical Trials

Opioid-Free Anesthesia in Modified Radical Mastectomy

Start date: January 1, 2018
Phase:
Study type: Observational

The aim of this study is to evaluate the efficacy of opioid-free general anesthesia for breast surgeries in female patients.