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NCT ID: NCT03946189 Completed - Clinical trials for Acute Respiratory Distress Syndrome

Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome

Start date: March 14, 2018
Phase:
Study type: Observational

In mechanically ventilated patients the PaO2/FiO2 ratio might not be the best reflection of the severity of ARDS. It does not incorporate variables and settings used during mechanical ventilatory support such as the positive end expiratory pressure (PEEP), inspiratory time to expiratory time ratio (Ti:Te), and the peak alveolar pressure (Palv). The aim is to identify a new oxygenation index for stratification of severity of ARDS

NCT ID: NCT03887312 Not yet recruiting - Depression Clinical Trials

Phone-Delivered Psychological Intervention (t-CETA) for Mental Health Problems in 8-16 Year-Old Syrian Refugee Children

t-CETA
Start date: April 1, 2019
Phase: N/A
Study type: Interventional

This study evaluates the effectiveness of t-CETA, a version of Common Elements Treatment Approach (CETA) adapted to be delivered over the telephone, in treating common mental health problems in 8-16 year old Syrian refugee children living in Lebanon. Children will be randomly assigned to receive either t-CETA or treatment as usual provided by Médecins du Monde, an NGO providing medical and mental health services to Syrian refugees in Lebanon. Symptoms of common mental health problems, including anxiety, depression, PTSD, and behavioural problems, and psychological well-being, will be measured before treatment, immediately after treatment, and three months after treatment is completed. Groups will be compared to determine if t-CETA is at least as effective as standard treatment provided by Médecins du Monde.

NCT ID: NCT03849248 Not yet recruiting - Development, Child Clinical Trials

Maternal Scent and Preterm Infant Nutrition

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

To study the effect of maternal scent on the oral feeding, behavior and stress level of premature infants hospitalized in the Neonatal intensive care unit and to assess its potential effect on their development at 18 to 24 months.

NCT ID: NCT03847675 Recruiting - Child Development Clinical Trials

Reach Out and Read Arabic to Promote Arabic Literacy in Toddlers

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

The goal of this study is to encourage parents to read Arabic books to their children in order for this to become a daily habit; by extension children will grow up loving to read Arabic books and ultimately improve their Arabic literacy. The investigators' hypothesis is that the "Reach Out and Read Arabic" intervention can be implemented in a middle income country setting where recruited participants will complete the study; and that the intervention will lead to higher proportion of parents reading Arabic books to their children compared to the control group.

NCT ID: NCT03836638 Not yet recruiting - Aging Clinical Trials

The Impact of Age on Botulinum Toxin Potency in Facial Rhytides Treatment

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Botulinum toxin is approved by the FDA for the treatment of facial wrinkles. Patients are usually older than 45 years and their main demand is to treat pre-existing facial wrinkles. However with the increasing popularity of this technique, younger patients, aged 25 to 35 years, are now seeking botulinum toxin injection as a preventive measure for rhytides. The usual dose used for the treatment of facial rhytides in a female patient older than 45 years is 50 units. No consensus exists concerning the dose of botulinum toxin that should be used in younger patients. Hypothesis: lower dose of botulinum toxin is sufficient to give good and long lasting results in young patients. The objective of this randomized open-label study is to evaluate the effect of lower doses of Botulinum toxin on the facial rythides in young patients.

NCT ID: NCT03836495 Recruiting - Energy Expenditure Clinical Trials

The Effect of Bread Fortification With Phosphorus and Lysine on Postprandial Glycaemia and Thermogenesis

Start date: February 6, 2019
Phase: N/A
Study type: Interventional

Wheat and wheat derived products are highly consumed around the world. They constitute the major dietary source of protein and energy for many individuals. Wheat contains moderate quantity of low quality protein lacking in some essential amino acids, primarily lysine, thus wheat based diets can't sustain optimal growth, and accordingly should be supplemented with lysine or complemented by another protein source of better quality to match human needs. However, human studies showed that wheat flour fortification with lysine was able to slightly improve growth, namely by increasing weight gain, but it did not however completely reverse growth impairment provoked by the consumption of wheat-based diets. The investigators developed interest in the role of phosphorus in health and diseased and believe that the modest impact of lysine fortification may due to low phosphorus availability of wheat products. Phosphorus content of cereals is mainly in the form of phytate that is not bioavailable. Supplementing a wheat gluten based diet with a combination of lysine and phosphorus was able to highly amplify the increase in weight gain and energy efficiency of rats as compared to lysine or phosphorus supplementation alone. Phosphorus is an essential mineral known to be directly involved in the production of ATP, which is essential for many metabolic processes including protein synthesis. The investigators believe that a better approach to enhance the quality of a wheat-based diet is through the supplementation with a combination of both lysine and phosphorus. The present study is designed to investigate the effect of white flour fortification with lysine and/or phosphorus on sensory properties, postprandial glycaemia and insulinemia, as well as postprandial thermogenesis. Most specifically, we aim to: 1. Determine the acceptability and assess sensory differences of the fortified breads. 2. Determine the glycemic response after ingestion of the different fortified breads. 3. Evaluate the variation in energy expenditure after the consumption of the fortified breads.

NCT ID: NCT03834935 Not yet recruiting - Pityriasis Alba Clinical Trials

Efficacy of Topical Pimecrolimus in the Treatment of Pityriasis Alba

Start date: March 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Pityriasis alba (PA) is a common benign skin disorder, that usually affects children and adolescents of darker phototypes. A history of atopic dermatitis is a well-known risk factor, and PA may be a minor manifestation of atopic dermatitis, although it can occur in nonatopic individuals as well. The objective is to evaluate the effect of topical pimecrolimus in the treatment of treatment of PA

NCT ID: NCT03827915 Recruiting - Atrial Fibrillation Clinical Trials

Double Sequential External Defibrillation in Patients With Atrial Fibrillation Refractory to DC Cardioversion

Start date: January 21, 2019
Phase: N/A
Study type: Interventional

Atrial fibrillation (AF) is a common cardiac arrhythmia that leads to increased risk of heart failure, hospitalization, thromboembolic events, and death. Restoration of normal heart rhythm is performed in many patients with AF to improve symptoms. In this study, the investigators will consider patients who fail 2 or more trials of DC cardioversion as having refractory AF. The aim of this study is to assess whether the use of double sequential defibrillation in patients with refractory AF has a higher success rate in reverting them to a normal heart rhythm than a third cardioversion. This is a phase III, randomized controlled, single-centered, superiority trial. All patients with AF admitted to the coronary care unit (CCU) for DC cardioversion, and refractory to at least two trials of DC cardioversion will be enrolled. Patients are randomized into two arms: the first will receive a third trial of DC cardioversion (standard of care) and the second will receive double sequential external defibrillation. The resolution of AF by reverting back to normal sinus rhythm is the primary outcome of the investigators. This will be determined using EKG (electrocardiogram) immediately after DC cardioversion or double sequential defibrillation.

NCT ID: NCT03816046 Completed - Hyperhidrosis Clinical Trials

Hyperhydrosis Treatment Using Botulinum Toxin

Start date: May 1, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to describe two safe and reproducible techniques for the treatment of hyperhidrosis using botulinum toxin. The same patient will receive two different injection technique in each armpit and will be evaluated subjectively and objectively.

NCT ID: NCT03814954 Recruiting - Clinical trials for Respiratory Distress Score

Nebulized Epinephrine vs. Salbutamol in Bronchiolitis Among Children

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Acute bronchiolitis, mostly secondary to infection due to Respiratory syncytial virus (RSV) is very common in infants under two years old. It is usually benign. However, the dyspnea it causes is a big concern for parents and this disease can take a severe form on certain particular ground thus constituting a frequent reason for hospitalization in pediatrics. Nebulized epinephrine showed more efficacy than nebulized salbutamol.