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Temporomandibular Disorder clinical trials

View clinical trials related to Temporomandibular Disorder.

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NCT ID: NCT06298786 Not yet recruiting - Fatigue Clinical Trials

Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).

F-6MMT
Start date: April 2024
Phase:
Study type: Observational

Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain, and headaches. TMDs are classified according to the DC/TMD instrument in which the joint and pain axes are evaluated. However, there is no evaluation of mandibular function, and TMDs can result in a decrease in jaw strength and resistance. This leads to an increase in the chewing fatigue. Reliable and time-effective diagnostic methods for evaluating masticatory function are crucial in the clinical setting because of the high prevalence of TMD. Chewing efficiency is essential for food preparation and nutrient absorption, and muscle fatigue is a common problem affecting chewing ability. Despite this, there is a lack of validated tests to evaluate chewing fatigue in patients with TMD, which makes its consideration unnoticed in clinical practice. The modified six-minute functional chewing test (F-6MMT) was proposed as a tool to evaluate chewing ability and fatigue in patients with TMD. This test is an adaptation of a previously designed test in which subjects with mitochondrial pathology were evaluated; however, the subjects were not instructed to perform functional chewing during the test. In this version, modifications are added so that the test is as functional as possible, allowing chewing to be evaluated in a standardized way, and cut-off points established between healthy subjects and subjects with TMD in terms of chewing capacity in general and fatigue in particular. This study will follow standardized reporting guidelines and recruit participants from diverse clinical settings.

NCT ID: NCT06265636 Not yet recruiting - Clinical trials for Temporomandibular Disorder

Electrical Stimulation of the Mandibular Nerve for Pain and Function Management in Temporomandibular Disorders

Origenkine
Start date: February 17, 2024
Phase: N/A
Study type: Interventional

Temporomandibular disorders (TMD) encompass dysfunction and pain of the masticatory muscles and temporomandibular joint (TMJ). Pain in the TMJ, restricted jaw movement, and joint sounds are common conditions in this disorder. This can impact patients' ability to perform daily activities such as eating, speaking, laughing, or yawning, significantly affecting their quality of life. The TMJ and masticatory muscles are innervated by the auriculotemporal branch and the mandibular nerve (V3), a branch of the trigeminal nerve. An estimated 60% to 70% of the population shows signs of TMD, of which up to 12% report intense symptoms requiring treatment. Percutaneous electrical nerve stimulation (PENS) could be a clinically relevant therapy in TMD patients applied through minimally invasive physiotherapy. To our knowledge, there are no trials evaluating the non-surgical clinical efficacy of PENS on the mandibular nerve. The project's objective is to assess the effectiveness of PENS on the mandibular nerve in this type of condition.

NCT ID: NCT06231212 Completed - Clinical trials for Temporomandibular Disorder

Efficacy of a Standardized Centella Asiatica Extract in Patients With Temporomandibular Disorder

TMD ECa233
Start date: August 5, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to test analgesic effect of ECa 233 in subjects with TMD. The main questions it aims to answer are: - Can ECa 233 reduce pain intensity score in subjects with acute TMD? - Can ECa 233 increase jaw functional movements in subjects with acute TMD? Participants will be separated into four groups, including placebo, ibuprofen, low-dosed Eca and high-dosed Eca groups.

NCT ID: NCT06214923 Not yet recruiting - Pain Clinical Trials

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)

VR TMD EEG
Start date: February 2024
Phase: N/A
Study type: Interventional

This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.

NCT ID: NCT06189612 Recruiting - Neck Pain Clinical Trials

Manual Therapy and Movement Control Exercises for Chronic Neck Pain. A Pilot Randomized Controlled Trial

Start date: May 25, 2023
Phase: N/A
Study type: Interventional

Chronic neck pain is a common and highly prevalent clinical entity among the population. It causes a high economic and financial burden. Commonly people with neck pain present temporomandibular disorders (TMD). These conditions are closely correlated with each other. Several studies have shown that patients with neck pain do have abnormalities in motor control, endurance capacities, and strength of the cervical and orofacial area. Several treatment modalities are available for neck pain that can be divided into pharmaceutical and non-pharmaceutical approaches. Among the non-pharmaceutical interventions, physiotherapy, manual therapy and exercises are of interest. The effect of treatment modalities is heterogeneous. Passive modalities often lack positive long-term outcomes. Therefore, our trial aims to measure the effects of a combined treatment, consisting in manual therapy and a movement control training for the neck region or for the temporomandibular region, respectively. The implementation of the temporomandibular movement control training is based on the assumption that there might be crossover effects between both regions, i.e., convergence of cervical and trigeminal sensory afferents between these two regions. We designed a parallel randomized controlled trial (RCT) with three intervention arms and a blinded assessor for outcomes that are clinician performed. This study is a pilot trial, so each group is expected to consist of 15 subjects. Both female and male patients between the ages of 18 and 65 will be included. Participants must suffer from idiopathic chronic neck pain (at least 3 months) and may also have symptomatic TMD disorders. The Primary Outcome will be neck pain disability measured by the Neck Disability Index (NDI). Secondary Outcomes will be Diagnostic Criteria (DC)/TMD (Axis I and Axis II), range of motion (CROM, FRT), CVA, PPT, CCFT, and both cervical and orofacial test batteries to assess motor control in each region. Patients are randomly assigned to one of the three intervention groups using a computer-generated sequence which is concealed. The three groups are: 1) clinical reasoning (CR) based physical therapy + cervical motor control training, 2) CR based physical therapy + orofacial motor control training, 3) CR based physical therapy + general coordination and strengthening exercises for the jaw and neck region. Prior to the start of treatment, participants will undergo an eligibility assessment. If the participant meet the inclusion criteria, the baseline assessment is conducted, and the treatment is planned following the prescription for physiotherapy in Germany. Treatment will comprise six 30-minute treatment sessions, which take place once a week over a period of 6 weeks. Upon completion of the six treatment sessions, the final examination is conducted, which includes the same assessments as the initial examination.

NCT ID: NCT06186830 Recruiting - Clinical trials for Temporomandibular Disorder

Cognitive Exercise Therapy Approach Biopsychosocial Questionnaire (BETY-BQ) in Patient With Temporomandibular Disorders

Start date: December 17, 2023
Phase:
Study type: Observational

The aim of this study is to investigate the validity, reliability, and responsiveness of the Cognitive Exercise Therapy Approach-Biopsychosocial Questionnaire (BETY-BQ) in individuals with temporomandibular disorder. The following are alternative hypotheses of the study: - BETY-BQ has significant convergence with the Patient Health Questionnaire-9 measuring depression. - BETY-BQ has significant convergence with the Patient Health Questionnaire-15 measuring physical symptoms. - BETY-BQ has significant convergence with the Generalized Anxiety Disorder-7 measuring anxiety. - BETY-BQ has significant convergence with the Short Form-36 measuring quality of life. - BETY-BQ has significant convergence with the Craniomandibular Pain and Disability Inventory measuring disability. - BETY-BQ has significant convergence with the Mandibular Function Impairment Questionnaire measuring function. - BETY-BQ has significant stability. - BETY-BQ has significant internal consistency.

NCT ID: NCT06186817 Recruiting - Clinical trials for Temporomandibular Disorder

Effectiveness of the Fascial Distortion Model on the Cervical Spine in Individuals With Temporomandibular Disorder

Start date: December 17, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to investigate the effectiveness of Manual Therapy Based on the Fascial Distortion Model (FDM) on the cervical spine by comparing it with Core Stabilization Training (CST) or Control in individuals with temporomandibular disorders. The main questions it aims to answer are: Is the effectiveness of the addition of FDM-based Manual Therapy to conventional therapy different from the addition of CST or control? Is the effectiveness of the addition of CST to conventional therapy different from the addition of FDM or control? All participants in the intervention groups will be given eight-week conventional therapy (Rocabado Exercises and Patient Education) in addition to FDM-based Manual Therapy or CST. Participants in the control group will not be given any therapy during the study. Neck pain intensity, hand grip strength, head posture, cervical muscle performance, cervical range of motion (function), disability, and quality of life will be assessed.

NCT ID: NCT06156345 Recruiting - Clinical trials for Temporomandibular Disorder

Additional Effect of Forward Head Posture Correction on Temporomandibular Dysfunction

Start date: March 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the additional correction effect of nerd neck on damaged jaw in people who suffers from jaw problems and nerd neck at the same time. The main question it aims to answer: • whether the additional correction of nerd neck impact the jaw features of pain and function. Participants will: - participants will be given the consent to sign first. - participants will be assessed to check jaw pain and function. - participants will be divided randomly into 2 groups. - Each group will be given the treatment sessions for 6 weeks. - participants will come back after 6 weeks for another last assessment. Researchers will compare regular treatment for Jaw with new device, regular only and dental treatment groups to see if there is improvement in jaw characteristics.

NCT ID: NCT06134310 Recruiting - Clinical trials for Temporomandibular Disorder

Efficacy of Manual Therapy Based on the Fascial Distortion Model in Individuals With Temporomandibular Disorder

Start date: November 7, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to investigate the efficacy of Manual Therapy Based on the Fascial Distortion Model (FDM) by comparing it with Core Stabilization Training (CST) or Control in individuals with temporomandibular disorders. The main questions it aims to answer are: - Is the efficacy of the addition of FDM-based Manual Therapy to conventional therapy different from the addition of CST or control? - Is the efficacy of the addition of CST to conventional therapy different from the addition of FDM or control? All participants in the intervention groups will be given eight-week conventional therapy (Rocabado Exercises and Patient Education) in addition to FDM-based Manual Therapy or CST. Participants in the control group will not be given any therapy during the study. Pain intensity, TMD severity, head posture, function, and disability will be assessed.

NCT ID: NCT06123351 Not yet recruiting - Clinical trials for Temporomandibular Disorder

Forward Head Posture Correction Impact on Temporomandibular Dysfunction

Start date: October 2025
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the effect of nerd neck correction on damaged jaw in people who suffers from jaw problems and nerd neck. The main question it aims to answer: - whether there are different effects of traditional nerd neck correction exercises, device correction method and dental splints on jaw features of pain and function. Participants will: - participants will be given the consent to sign first. - participants will be assessed to check jaw pain and function. - participants will be divided randomly into 3 groups. - Each group will be given the treatment sessions for 6 weeks. - participants will come back after 6 weeks for one last assessment. Researchers will compare traditional, new and dental treatment groups to see if there is improvement in jaw characteristics.