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NCT ID: NCT05693402 Completed - Surgery Clinical Trials

Opioid-Free Anesthesia in Modified Radical Mastectomy

Start date: January 1, 2018
Phase:
Study type: Observational

The aim of this study is to evaluate the efficacy of opioid-free general anesthesia for breast surgeries in female patients.

NCT ID: NCT05646784 Not yet recruiting - Mood Disorders Clinical Trials

Gut Microbiota in Mood Disorders in Lebanese Population

Start date: May 29, 2023
Phase: N/A
Study type: Interventional

This study aims to evaluate the pathophysiological aspects of the role of inflammation and gut microbiota in mood disorders, in particular in depression, and their therapeutic implications on a cohort of the Lebanese population. Specific objective: The evaluation of probiotic intake (CEREBIOME®, Lallemand Health Solutions Inc., Mirabel, Canada) on depressive patients and the inflammatory state. Evaluate the effect of oral intake of a probiotic agent, on clinical and plasma inflammatory markers, in a subgroup of target patients versus a subgroup treated with placebo, in combination with conventional treatment.

NCT ID: NCT05628389 Not yet recruiting - Smoking Cessation Clinical Trials

Phone Enabled Implementation of Cessation Support (PHOENICS)

Start date: October 2023
Phase: N/A
Study type: Interventional

The tobacco use burden in Lebanon is exceptionally high: 35% of adults are current cigarette smokers and 39% are current waterpipe smokers. Although the World Health Organization endorses evidence-based interventions for population-level tobacco dependence treatment, recommended treatments are not integrated as a routine part of primary care in Lebanon, as is the case in other low-resource settings. The objective of this proposal is to evaluate the comparative effectiveness of promising multi-component interventions for implementing evidence-based cessation treatment in Lebanon's national system of primary health care centers.

NCT ID: NCT05604677 Completed - Breast Neoplasm Clinical Trials

Factor Influencing Breast Surgery Type Decision-Making

Start date: June 15, 2022
Phase:
Study type: Observational [Patient Registry]

The aim of this observational study is to determine the factors influencing the decision-making process for breast surgery type, in Lebanese women likely to face breast cancer. The main questions it aims to answer are the presence or not of a correlation between the type of choice and the following data: - Demographic - Health Status - Several factors that may influence the decision Participants will complete a well-structured and organized online survey

NCT ID: NCT05558800 Completed - Implant Geometry Clinical Trials

Bone-To-Implant Contact At 4- And 6-Week Healing Stages in Implants With Different Surfaces.

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Objective: Implant surface topography is a key element in achieving osseointegration. Nanostructured surfaces have shown promising results in accelerating and improving bone healing around dental implants. The main objective of the present clinical study is to compare, at 4 and 6w, bone-to-implant contact in implants having either machined surface (MAC), SLA medium roughness surface or a Nanostructured Calcium-Incorporated surface (XPEED®). Thirty five mini-implants with 3 different surface treatments (XPEED® (n=16) - SLA (n=13) - Machined (n=6)), were placed in the posterior maxilla of 11 patients then retrieved at either 4 or 6w in a randomized split-mouth study design.

NCT ID: NCT05530928 Recruiting - Clinical trials for Family Planning Services

The Importance of Including Reproductive Life Plan Counseling During Contraceptive Counseling

Start date: September 10, 2022
Phase: N/A
Study type: Interventional

The reproductive life plan is a protocol intended to promote preconception planning, improve reproductive health and increase health knowledge. The aim of the study is to evaluate the importance of including the reproductive life plan counseling during contraceptive counseling.

NCT ID: NCT05512273 Completed - Implant Osteotomy Clinical Trials

Implant Site Preparation With Piezosurgery vs Conventional Drills in Terms of Operation Time, Implant Stability and Bone Density

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

The preparation of the implant site has a major influence on the success rate and long-term survival of dental implants. Piezoelectric devices and special implant drilling inserts are now emerging to replace conventional drills.

NCT ID: NCT05430334 Recruiting - Nicotine Dependence Clinical Trials

Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency

Start date: July 13, 2022
Phase: N/A
Study type: Interventional

Electronic nicotine delivery systems (ENDS) heat and vaporize a nicotine-containing liquid to produce an aerosol that can deliver nicotine to the blood and the brain. ENDS use has increased rapidly in the last decade, especially among youth: over 20% of US high school students are current ENDS users, and there is evidence of nicotine dependence in this population. Federal legislation has been proposed that would restrict ENDS liquid nicotine concentration to make ENDS "significantly less addictive and appealing to youth." However, these and other efforts to curb addiction by limiting nicotine liquid concentration are unlikely to succeed because nicotine emissions from ENDS depend on multiple variables. To achieve the intended public health aims, regulations targeting addiction must focus on nicotine delivery, not nicotine concentration. While nicotine delivery cannot be regulated directly, the rate at which an ENDS emits nicotine, the "nicotine flux", can be regulated and, importantly, predicted based on a few device design and operating variables. However, to date there is no empirical evidence demonstrating the relationship between flux and delivery, nor between flux and the subjective effects that support nicotine dependence. Closing this gap is essential for providing an effective framework for regulating ENDS. At the American University of Beirut, the investigators will assess the relationship between nicotine flux, form, and subjective effects. Participants will use ENDS devices with varying nicotine fluxes and forms. Dependency measures, such as urge to smoke, craving, and abstinence, will be assessed. The outcome will indicate the degree to which nicotine flux/form influence subjective effects related to dependency, puffing intensity, and exposure to toxicants. In summary, this project will provide the empirical evidence needed for public health agencies to use nicotine flux as an encompassing and convenient construct to regulate nicotine delivery from ENDS.

NCT ID: NCT05349214 Recruiting - Sjogren Syndrome Clinical Trials

Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjögren's Syndrome

NEPTUNUS-2
Start date: August 4, 2022
Phase: Phase 3
Study type: Interventional

A randomized, double-blind, placebo controlled, 3-arm multicenter phase 3 study to assess the efficacy and safety of ianalumab in patients with active Sjögren's syndrome (NEPTUNUS-2)

NCT ID: NCT05348915 Enrolling by invitation - Sickle Cell Disease Clinical Trials

A Study to Evaluate the Long-term Safety of Inclacumab Administered to Participants With Sickle Cell Disease

Start date: March 29, 2022
Phase: Phase 3
Study type: Interventional

This study is an open-label study to evaluate the safety of long-term administration of inclacumab in participants with sickle cell disease (SCD). Participants in this study will have completed a prior study of inclacumab.