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NCT ID: NCT04827888 Completed - Obesity Clinical Trials

Effect of BMI on Postoperative Morbidities of Orthopaedic Procedures

Start date: January 1, 2012
Study type: Observational [Patient Registry]

Obesity is associated with poor surgical outcome and complications. The literature does not provide a comprehensive view on the effect of body mass index (BMI) on perioperative outcomes in orthopedic surgeries. Therefore, we aim to determine the effect of BMI on 30-day perioperative outcomes in patients undergoing the first 25 most commonly performed orthopedic surgeries using a retrospective cohort study design. The knowledge of the effect of BMI on orthopedic surgeries will improve the knowledge of surgeons about the expected morbidities.

NCT ID: NCT04822454 Completed - Clinical trials for Medical Students Well-being and Anxiety

Early Exposure of Medical Students to Night Shifts: Impact on Well-being and Anxiety

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This is an interventional study assessing the impact of 'shadowing night shifts' early during medical school, on the wellbeing and level of anxiety of a students during their first official night shifts.

NCT ID: NCT04813471 Recruiting - Covid19 Clinical Trials

Managing Endothelial Dysfunction in Critically Ill COVID-19 Patients at LAUMCRH

Start date: January 20, 2021
Phase: Phase 3
Study type: Interventional

COVID-19 Infection has been found to cause endothelial dysfunction and most of the adverse events stem to this mechanism. So we seek to target endothelial dysfunction in critically Ill patients with covid by giving them an endothelial protocol ( L-arginine, Folic Acid, Statin, Nicorandil, Vitamin B complex) and monitor clinical outcome in those patients.

NCT ID: NCT04813367 Not yet recruiting - Clinical trials for Twisted Fallopian Tube

Twisted Fallopian Tubes

Start date: April 2021
Study type: Observational

Isolated tubal torsion is a very rare event already in adults (1: 1.5 million women), it remains exceptional in children without being able to find a prevalence in the literature. The causes can be malformative or idiopathic, but even that remains unknown. Because of the scarcity, surgical treatment is not standardized and left to the good care of the surgeon in charge.

NCT ID: NCT04790149 Completed - Clinical trials for Spinal Cord Injuries

Effectiveness of NEUROM Combined With tDCS to Guide Motor Recovery in Paraplegics Patients

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

In a traditional view going back to 1800, spinal cord has been described as a protected bundle of nerves that connects the brain to the body. Galen contended that spinal cord mediates motor, sensory and some of the autonomic functions below the neck. Traumatic Spinal Cord Injury (TSCI) is a catastrophic unexpected and devastating event that can be occurred along the spinal column (cervical, thoracic, and lumbar). A global-incident rate (2007) is estimated at 23 TSCI cases per million (179312 cases per annum). TSCI can often results in a life-threatening condition that includes varying degrees of motor paralysis and sensory loss and impairment of bowel, bladder, sexual, and other physiologic functions. In this study, investigators suggest a new experimental rehabilitative protocol for TSCI patients called Neural Motor Recruitment Method (NEUROM). This method is based on the mentioned histological and/or functional reorganization model after TSCI, on the MI concepts and the targeted sensory inputs related to motor recovery. The hypothesis here is that NEUROM can enhance sparing- induced plasticity and increase motor and sensory recovery in SCI patients especially when combined to tDCS.

NCT ID: NCT04783220 Not yet recruiting - Early Intervention Clinical Trials

PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed results. In low to middle-income countries, clinically relevant and effective low cost interventions empowering parents have yet to be established.

NCT ID: NCT04761445 Active, not recruiting - Implant Stability Clinical Trials

Comparison Between Two Different Tissue-Level Implant Systems: A Prospective Clinical Study

Start date: January 10, 2019
Phase: N/A
Study type: Interventional

The objective of this prospective study is to compare clinically and radiographically two different tissue-level implants, in partially edentulous patients in the posterior area of the maxilla and mandible. The primary objective of the study was to track the crestal bone level changes around the two implant systems. Secondary objectives were implant stability as well as initial soft tissue thickness which were evaluated throughout this study.

NCT ID: NCT04758078 Recruiting - Clinical trials for Respiratory Distress

Inhaled Budesonide in Transient Tachypnea of the Newborn

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Background: Transient tachypnea of the newborn (TTN) caused by lung edema resulting from delayed absorption of fetal alveolar lung fluid and is a common cause of admission of late preterm and full-term infants to neonatal intensive care units. Infant born by C-section and those with perinatal asphyxia, umbilical cord prolapse or certain maternal condition (asthma, diabetes, or analgesia) are more prone to develop TTN. Conventional treatment involves appropriate oxygen administration and continuous positive airway pressure in some cases. Hastening the clearance of lung liquid should shorten the duration of the symptoms and reduce complications. Objectives: This study aims to determine the effectiveness of inhaled budesonide in the treatment of this disorder through determining whether it reduces the duration of oxygen therapy and respiratory symptoms and shortens hospital stay in term infants with transient tachypnea of the newborn

NCT ID: NCT04718844 Recruiting - Clinical trials for Non-transfusion-dependent Thalassemia

A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome

Start date: March 2021
Phase: Phase 1
Study type: Interventional

This study will investigate the safety and tolerability of SLN124 in patients with Thalassaemia or patients with Very Low- and Low-risk Myelodysplastic Syndrome after single ascending s.c. doses and multiple doses in healthy male and female subjects. Up to 7 cohorts of 56 patients with Thalassaemia and up to 7 cohorts of 56 patients with Myelodysplastic Syndrome will be enrolled. Each subject will receive single or multiple doses of SLN124 or placebo given by subcutaneous (s.c) injection.

NCT ID: NCT04709874 Not yet recruiting - Pain, Shoulder Clinical Trials

Paravertebral Block vs. Suprascapular Block for Treatment of Frozen Shoulder

Start date: February 2021
Phase: N/A
Study type: Interventional

Background: Adhesive capsulitis, or frozen shoulder, is a major orthopedic condition that causes pain and functional limitation. Although different nonsurgical conservative therapies such as physical therapy, nonsteroidal anti-inflammatory drugs, and corticosteroid injections have been used, yet there is no standard treatment for frozen shoulder. Objectives: The primary objective of this study is to compare the effectiveness of nerve stimulator guided paravertebral block versus suprascapular block for treatment of frozen shoulder. The primary outcome is pain measured through the Visual Analogue Scale (VAS) over a follow up period of 6 months. Methods: This is a prospective randomized clinical trial that will be conducted between February 2021 and January 2022. Patients will be randomly allocated into two groups. Group I will receive paravertebral block guided by a nerve stimulator. Group II patients will receive suprascapular nerve block. Patients will be followed up at week 1, month 1, month 3 and month 6.