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NCT ID: NCT02157649 Completed - Cough Clinical Trials

Single Dose Trial of Extended Release Combination Tablet Codeine and Guaifenesin

Start date: June 2014
Phase: Phase 1
Study type: Interventional

The objectives of this study are (a) to determine if drug levels from a single dose of an extended-release Codeine/Guaifenesin tablet are similar to an immediate-release tablet given every four hours containing lower doses considered safe for over-the-counter use; (b) to evaluate if food affects the drug levels of this extended-release Codeine/Guaifenesin tablet after a single administration; and (c) to assess the safety and tolerability of the Codeine/Guaifenesin extended-release and immediate release tablet formulations.

NCT ID: NCT02157506 Completed - Heart Failure Clinical Trials

A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure

Start date: June 30, 2014
Phase: Phase 2
Study type: Interventional

A randomized, double-blinded, placebo-controlled study of continuous 6-hour IV infusions of CXL-1427 in hospitalized patients with systolic heart failure.

NCT ID: NCT02153411 Completed - Asthma Clinical Trials

Multicentric, Transversal, Descriptive, Epidemiological Study on the Management of Asthma in Asthmatic Middle East Adult Population

ESMAA
Start date: June 2014
Phase: N/A
Study type: Observational

Descriptive study on the management of asthma in asthmatic Middle East adult population : Algeria,Egypt, Irak,Iran, Jordan, Koweit, Lebanon, Qatar,Saudi,Tunisia, UAE

NCT ID: NCT02146209 Completed - Clinical trials for Bacterial Infections

Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate.

Start date: June 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether Terix Labs Ltd Metronidazole benzoate (400 mg Metronidazole Per Sachet Oral Granules) is bioequivalent to 500 mg Sanofi-aventis Flagyl 125 mg/5 ml (125 mg Metronidazole Per 5 ml Suspension) and to Zentiva Flagylâ„¢ 400 mg Tablets (400 mg Metronidazole Per Film Coated Tablets).

NCT ID: NCT02118519 Completed - Clinical trials for Osteoarthritis, Knee

Mesenchymal Stem Cells in Knee Cartilage Injuries

Start date: January 2014
Phase: Phase 2
Study type: Interventional

Induction of autologous repair chondrogenesis to regenerate injured articular cartilage using bone marrow mesenchymal stem cells (MSCs) after in vitro expansion under restricted culturing conditions.

NCT ID: NCT02093923 Completed - Clinical trials for Hereditary Angioedema (HAE)

A Double-Blind, Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of DX-2930 in Hereditary Angioedema Participants

Start date: May 14, 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) profile of multiple subcutaneous administrations of DX-2930 across a range of doses in HAE participants.

NCT ID: NCT02092467 Completed - Clinical trials for Arthritis, Rheumatoid

Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis

Start date: March 14, 2014
Phase: Phase 4
Study type: Interventional

This post-marketing study is designed to compare the safety of tofacitinib versus TNF inhibitor with respect to major cardiovascular adverse events and malignancies, excluding non-melanoma skin cancers when given to subjects with rheumatoid arthritis. Other safety events, including non-melanoma skin cancers, hepatic events, infections, and efficacy parameters will be collected and evaluated in the study.

NCT ID: NCT02013349 Completed - Clinical trials for Coronary Artery Disease

DESolve Post-Approval Study

Start date: April 22, 2014
Phase: N/A
Study type: Interventional

To evaluate the long-term safety and performance of the DESolve Novolimus Eluting Bioresorbable Coronary Scaffold System

NCT ID: NCT02009956 Completed - Clinical trials for Coronary Artery Disease

EXCELLA Post-Approval Study

Start date: February 26, 2014
Phase: N/A
Study type: Interventional

To evaluate long-term safety and performance of the DESyne Novolimus Eluting Coronary Stent System and the DESyne BD Novolimus Eluting Coronary Stent System

NCT ID: NCT02005380 Completed - Alzheimer's Disease Clinical Trials

Usability Study of Spaced Retrieval Exercise Using Mobile Devices for Alzheimer's Disease Rehabilitation

Start date: November 2013
Phase: N/A
Study type: Observational

The focus of this work is to explore the use of modern mobile technology to enable people with Alzheimer's disease to improve their abilities to perform activities of daily living and hence to promote independence and participation in social activities. This work also aims at reducing the burden on caregivers by increasing the AD patients' sense of competence and ability to handle behavior problems.