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NCT ID: NCT06292988 Not yet recruiting - Clinical trials for Medullary Thyroid Cancer

Predictive Factors for Medullary Thyroid Cancer Aggressiveness

MYELO
Start date: March 1, 2024
Phase:
Study type: Observational

This study is a retrospective study trying to find the predictive factors for medullary thyroid aggressiveness in terms of tumor metastasis and patients' survival.

NCT ID: NCT06187324 Not yet recruiting - Biomarkers Clinical Trials

Accuracy of Host-derived Biomarkers in Diagnosing Symptomatic and Asymptomatic Apical Periodontitis

Start date: December 30, 2023
Phase: N/A
Study type: Interventional

Apical lesions usually present clinically as a chronic infection, remaining as asymptomatic apical periodontitis(AAP). Because the balance among inflammation and bacteria is a dynamic process, AAP may undergo an acute exacerbation and become symptomatic, presenting as symptomatic apical periodontitis or acute abscess, or it may evolve from the acute to the chronic stage. Identification of specific biomarker could help in establishing more accurate diagnosis. Biological marker serves as a parameter that is indicative of underlying physiology and health of the tissue. It is measurable as well as quantifiable. The aim of this study: To assess the level of potential biomarkers in asymptomatic and symptomatic apical Periodontitis, and to determine the prediction potential of the same biomarkers for the outcome of endodontic treatment after 1year recall…

NCT ID: NCT06044246 Not yet recruiting - Dental Implantation Clinical Trials

Influence of Human Platelet Derivatives on Dental Implant

Start date: June 20, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to evaluate the benefit of PRF membrane on bone around dental implant in patients who need treatment with dental implant. Aims of the study: - To study the effect of PRF membrane (with or without bone substitute on increasing bone dimension around dental implant. - To investigate the effects of compositions of PRF (platelets count, WBC count) on bone healing.

NCT ID: NCT06037070 Not yet recruiting - Dental Implant Clinical Trials

Impact of Biological Factors on Dental Implant

Start date: May 10, 2024
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to compare the response of different bone densities to treatment with Platelet Rich Fibrin (PRF) in patients who need treatment with dental implant. The main questions it aims to answer are: - To investigate if bone reaction to PRF differ with different bone densities. - To study the effect of PRF on dental implant healing and to assess its effectiveness in accelerating osseointegration. Participants who need treatment with dental implant will be planned to include in this study and will be asked if they are willing to participate in this study voluntarily. All the participants will be given an information sheet and a consent form which provides simple description about the present study and its importance to insure voluntary participation. The patients will be aware that they are completely free to withdraw from the research any time during the research time. Platelet Rich Fibrin will be injected inside the hole that prepared to place dental implant in. Bone density will be evaluated, degree of osseointegration will be monitored.

NCT ID: NCT06031961 Not yet recruiting - Anesthesia Clinical Trials

The Premedication Properties of Oral Melatonin in Pediatrics Undergoing Therapeutic Cardiac Catheterization

Start date: September 10, 2023
Phase: N/A
Study type: Interventional

The evaluation of oral melatonin efficacy as premedicant agent in pediatrics undergoing elective cardiac interventions is the primary outcomes of our trail.

NCT ID: NCT05621577 Not yet recruiting - Clinical trials for Sleep Apnea, Obstructive

Obstructive Sleep Apnea Patients Treated With Mandibular Advancement Device

Start date: February 5, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate efficacy of mandibular advancement device (MAD). on treating obstructive sleep apneas, symptoms, Apnea/Hypopnea Index (QHI) and the Respiratory Arousal Index (AHI/REI) and peripheral capillary oxygen saturation (SpO2) Range, PULSE in patients with mild to moderate obstructive sleep apnea/hypopnea syndrome, and evaluating potential dental side effects

NCT ID: NCT05540431 Not yet recruiting - Uremic Toxin Clinical Trials

Evaluation of Protective Effect of Activated Charcoal and Probiotic Against Progression of Chronic Kidney Disease

Start date: September 25, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Investigate the nephroprotective effect of Activated Charcoal and Probiotic in limiting the progression of renal impairment in patients with chronic kidney disease and improving of renal function test and phosphate level. Condition or disease: chronic kidney disease

NCT ID: NCT05222425 Not yet recruiting - Sars-cov-2 Clinical Trials

Treatment of Non-severe Covid-19 Outpatients With Xagrotin, Phase 3

Start date: June 1, 2022
Phase: Phase 3
Study type: Interventional

This is an interventional, multi-center, randomized study. Adults with confirmed covid-19 disease not more than 10 days before enrollment date will be recruited (n=1000). Patients in same condition who get treated with standard of care will be randomly assigned to the control group (n=1000), and patients in same condition who get treated with standard of care will be randomly assigned to the placebo group (n=1000). The investigators analyze the effect of Xagrotin, and also investigate impact of different characteristics for instance gender, age, duration of disease, smoking habits and concomitant diseases on the outcome.

NCT ID: NCT04788979 Not yet recruiting - Clinical trials for Periodontal Diseases

The Adjunctive Use of Melatonin Therapy in the Treatment of Obese Periodontitis Patients (Clinical and Immunological Study).

Start date: April 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the effect of adjunctive systemic administration of melatonin to mechanical non- surgical periodontal therapy in obese patients with periodontitis.