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NCT ID: NCT00699374 Terminated - Clinical trials for Carcinoma, Hepatocellular

Study Of Sunitinib Malate Versus Sorafenib In Patients With Inoperable Liver Cancer

Start date: July 2008
Phase: Phase 3
Study type: Interventional

The study will evaluate the efficacy and safety of sunitinib (Arm A), given at 37.5 mg orally once daily, compared to sorafenib (Arm B), given orally at 400 mg twice daily, in patients with inoperable liver cancer. A total number of 1200 patients will be enrolled, 600 on Arm A and 600 on Arm B. Study treatment may be adjusted based on patient tolerance. and will be given until disease progression, occurrence of unacceptable toxicity, or other withdrawal criteria are met. After discontinuation of study treatment, patients will be followed up in order to collect information on further antineoplastic therapy and survival.

NCT ID: NCT00662597 Terminated - Clinical trials for Non-Small Cell Lung Cancer

ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer

ATRACT-1
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if adding ASA404 to standard chemotherapy makes the cancer treatment more effective in patients with advanced lung cancer.

NCT ID: NCT00625898 Terminated - Breast Cancer Clinical Trials

BETH Study: Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus Bevacizumab

BETH
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The trial will determine the value of adding bevacizumab to chemotherapy plus trastuzumab in patients with resected node-positive or high risk node-negative, HER2-positive breast cancer.

NCT ID: NCT00596830 Terminated - Clinical trials for Carcinoma, Non-Small-Cell Lung

Carboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced NSCLC Of Squamous, Large Cell And Adenosquamous Carcinoma Histology

Start date: April 2008
Phase: Phase 3
Study type: Interventional

Determine whether the addition of CP- 751,871 in combination with paclitaxel plus carboplatin prolongs survival in patients with locally advanced (Stage IIIB with pleural effusion) or metastatic (Stage IV or recurrent) NSCLC of non adenocarcinoma histology.

NCT ID: NCT00585312 Terminated - Clinical trials for Adenomatous Polyposis Coli

Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP)

CHIP
Start date: September 2006
Phase: Phase 3
Study type: Interventional

To test whether celecoxib can be used to prevent colon polyp formation in children with familial adenomatous polyposis (FAP).

NCT ID: NCT00568308 Terminated - Cancer Clinical Trials

Phase III Study of PI-88 in Post-resection Hepatocellular Carcinoma

PATHWAY
Start date: December 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if PI-88 is effective and safe in patients who have had surgery to remove primary liver cancer.

NCT ID: NCT00562965 Terminated - Clinical trials for Lymphoma, Follicular

Study Comparing Inotuzumab Ozogamicin In Combination With Rituximab Versus Defined Investigator's Choice In Follicular Non-Hodgkin's Lymphoma (NHL)

Start date: November 2007
Phase: Phase 3
Study type: Interventional

This protocol is designed to assess the efficacy and safety of inotuzumab ozogamicin given with rituximab compared to a defined investigator's choice therapy. Subjects will be randomized to one of these two arms of the study.

NCT ID: NCT00548496 Terminated - Fracture Healing Clinical Trials

A Phase IIa Study Of Men And Post-Menopausal Women With A Fractured Distal Radius

Start date: September 20, 2007
Phase: Phase 2
Study type: Interventional

This is a study designed to test the safety and effectiveness of SB-751689 in the treatment of a distal radius fracture in post-menopausal women and men in comparison to placebo to determine if healing time of the fracture can be decreased.

NCT ID: NCT00524030 Terminated - Epilepsies, Partial Clinical Trials

Efficacy And Safety Study Of Pregabalin (Lyrica) As Monotherapy In Patients With Partial Seizures

Start date: September 2007
Phase: Phase 3
Study type: Interventional

This study will determine the safety and efficacy of pregabalin (Lyrica) when administered by itself (without any other anti-epileptic medication) to epilepsy subjects for the treatment of partial seizures. The duration of the trial is about 6 months.

NCT ID: NCT00508274 Terminated - Neoplasms, Breast Clinical Trials

Lapatinib +Capecitabine Treatment for Advanced Metastatic Breast Cancer in Women From China

Start date: July 18, 2007
Phase: Phase 3
Study type: Interventional

Local study in China and Hong Kong to evaluate safety and efficacy in lapatinib + capecitabine in women with Human epidermal growth factor receptor 2 (HER2) positive advanced or metastatic breast cancer.