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NCT ID: NCT06380010 Completed - Clinical trials for Polycystic Ovary Syndrome

Mediterranean Diet Intervention in Adolescents With Polycystic Ovary Syndrome

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

The aim of the present randomized controlled study was to examine wether a clinical decision support stystem would increase the adherence to the Mediterranean diet (MD) of adolescent girls, aged 15-17 years, diagnosed with polycystic ovary syndrome. The intervention lasted for 3 months and in total, 40 girls were randomly assigned to either the MD group (n=20) or a Control group receiving general nutritional advice (n=20). Anthropometry, nutritional intake, psychological well-being, and blood markers were analyzed at the begninning and the end of the trial.

NCT ID: NCT06379022 Completed - Clinical trials for Periodontal Diseases

Proteomic Analysis of Newly Restored Single Implants

Start date: December 3, 2018
Phase:
Study type: Observational [Patient Registry]

In 10 systemically healthy non-smokers, free of periodontitis, one newly restored implant (baseline-T0) and one corresponding tooth were followed over 12 months (T1). All implants were screw-retained, and platform-switched. Oral hygiene was closely monitored during the study. Probing pocket depth (PPD), attachment levels (CAL), bleeding and plaque indices and crevicular fluid were collected from an implant-site (PICF) and a tooth-site (GCF). Total proteomic profiles in PICF and GCF were investigated using label-free quantitative proteomics.

NCT ID: NCT06370260 Completed - Quality of Life Clinical Trials

Assessing the Efficacy of a Hydrogen Peroxide Gel for Oral Wound Healing and Oral Hygiene

Start date: May 2, 2023
Phase: N/A
Study type: Interventional

This study aims to assess the effectiveness and safety of a hydrogen carbamide/peroxide gel, called UNISEPT® ORAL GEL, in promoting oral wound healing, alleviating postoperative symptoms, and enhancing oral hygiene. Study participants will include individuals with any suspicious lesion in their gums or the roof of their mouth. They will undergo a procedure to remove a small piece of tissue for testing (biopsy) in order to confirm the diagnosis.This is a standardized diagnostic procedure that involves the use of a punch, which is a plastic handpiece with a cylindrical cutting blade. Subsequently, the wound heals naturally without the need for sutures. Researchers are comparing this gel with a placebo (a look-and-taste-alike substance that contains no active ingredients) to see if it is helpful with healing of wounds in the mouth and associated symptoms, improving oral hygiene. Participants randomly get the hydrogen carbamide/peroxide gel or the placebo one to use for 14 days after the biopsy. The researchers will not know which one they are providing as the gel tubes will be identical. Oral wound healing, postoperative symptoms (such as pain, eating and speech difficulties), oral hygiene (dental plaque and gingival inflammation) and quality of life are assessed during a 14-day period after the biopsy. Participants are required to visit the clinic three times, one for the initial biopsy, one at 7 days and one at 14 days after the biopsy. They are asked to fill in some questionnaires, while certain procedures (taking a photo the site of the biopsy) and assessments (like evaluating the dental plaque and gingival inflammation) take place. During the first week they, also, keep a diary of their symptoms, as instructed.

NCT ID: NCT06293859 Completed - Healthy Clinical Trials

Effect of 12-week Probiotic Consumption Immobilized on Oat Flakes on Blood and Urine Biomarkers and Human Microbiome

FOODBIOMES CT2
Start date: February 15, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical trial was to evaluate the effects Lactococcus cremoris spp. im-mobilized on oat flakes on human microbiome and blood and urine biomarkers of associated with human health.

NCT ID: NCT06269796 Completed - Child Development Clinical Trials

Identification of Neuromotor Signs in Preschool Children Suspected of Developmental Coordination Disorder

Start date: March 1, 2021
Phase:
Study type: Observational

This prospective study aimed to detect neuromotor signs early in preschool children suspected of Developmental Coordination Disorder (DCD). Preschool children aged 3-5 years old from municipal kindergartens in Thessaloniki participated in this study. The Little DCDQ questionnaire and the BOT-2 (Bruininks-Oseretsky Test of Motor Proficiency) were used for assessment.

NCT ID: NCT06237517 Completed - Thermoregulation Clinical Trials

Assessment of Vasomotion of People With Idiopathic Chilblains

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

Chilblains, also known as perniosis, is a non-freezing cold injury causing painful inflammatory skin lesions. Chilblains typically affect the dorsal feet or hands, causing inflammatory skin lesions that are often painful, and their pathogenesis remains only partly understood. To improve diagnosis and management, it is vital to focus entirely on chilblains and consider the patient-related and environmental factors that characterize this disorder. Because of this, it's critical to investigate the thermoregulatory function, of individuals with idiopathic chilblains while they are exposed to various environmental conditions (cold and neutral environments).

NCT ID: NCT06203665 Completed - Atelectasis Clinical Trials

Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver

Start date: June 7, 2023
Phase: N/A
Study type: Interventional

To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.

NCT ID: NCT06185127 Completed - Anesthesia Clinical Trials

Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy

Start date: September 1, 2019
Phase: Phase 3
Study type: Interventional

Sedation during flexible bronchoscopy (FB) should maintain an adequate respiratory drive, ensure maximum comfort for the patient, and warrant that the objectives of the procedure are achieved. Nevertheless, the optimal sedation method for FB has yet to be established. This study aimed to compare the standard recommended combination of midazolam-fentanyl (MF) with that of dexmedetomidine-ketamine (DK) for patient sedation during FB. Patients subjected to FB were randomly assigned to a DK (n=25) and an MF group (n=25). The primary outcome was the rate of critical desaturation events (arterial oxygen saturation <80% with nasal oxygen supply 2 L/min). Secondary outcomes included sedation depth, hemodynamic complications, adverse events, and patient and bronchoscopist satisfaction.

NCT ID: NCT06163937 Completed - Appetitive Behavior Clinical Trials

Acute Effects of Fruit Juices Consumption on Postprandial Glycemic Responses and Satiety

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

This study investigated the acute effects of two fruit juices on postprandial glycemic responses and satiety in healthy individuals

NCT ID: NCT06141395 Completed - Pneumonia Clinical Trials

NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification

BIOARTE
Start date: November 16, 2023
Phase:
Study type: Observational

Rapid detection of microorganisms is a promising approach towards early administration of appropriate antibiotics for sepsis. This study aims to investigate the potential of a new NGS platform for the rapid diagnosis of circulating bacteria in blood.