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NCT ID: NCT00706238 Terminated - Melanoma Clinical Trials

MAGE-A3 Antigen-Specific Cancer Immunotherapeutic in Patients With Progressive Metastatic Cutaneous Melanoma

Start date: September 29, 2008
Phase: Phase 2
Study type: Interventional

This study is being done to evaluate the safety and the clinical activity of MAGE-A3 Antigen-Specific Cancer Immunotherapeutic in patients with unresectable and progressive metastatic cutaneous melanoma.

NCT ID: NCT00705549 Terminated - Clinical trials for Non-Small-Cell Lung Cancer

Individualized Therapy Based of Tumoral mRNA Levels of ERCC1, RRM1 and BRCA1 in Advanced Non-Small-Cell Lung Cancer

Start date: February 2008
Phase: Phase 2
Study type: Interventional

This is a prospective pilot phase II trial, in patients with wet stage IIIb and IV NSCLC using chemotherapy regimens which will be defined according to the pharmacogenomic profile (tumoral expression of ERCC1, BRCA1 and RRM1) of the tumor cells.

NCT ID: NCT00694200 Terminated - Breast Cancer Clinical Trials

Vinorelbine Metronomic Plus Bevacizumab as Salvage Therapy for Breast Cancer

Start date: April 2008
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy of metronomic oral vinorelbine taken three times a week without break plus bevacizumab as salvage treatment in patients with metastatic breast cancer.

NCT ID: NCT00681876 Terminated - Colorectal Cancer Clinical Trials

Phase II Study of Avastin + Erbitux + Irinotecan as 2nd Line Treatment of Colorectal Cancer

Start date: April 2008
Phase: Phase 2
Study type: Interventional

This phase II study will evaluate the efficacy of the combination of two monoclonal antibodies (Avastin + Erbitux) with irinotecan, in patients with colorectal cancer progressed after 1st line treatment with FOLFIRI Avastin or XELIRI Avastin.

NCT ID: NCT00679627 Terminated - Alzheimer's Disease Clinical Trials

A Study of Galantamine Used to Treat Patients With Mild to Moderate Alzheimer's Disease

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness and safety of 2 years of treatment with galantamine as compared with placebo of patients who have mild to moderately severe Alzheimer's disease (AD).

NCT ID: NCT00673049 Terminated - Clinical trials for Carcinoma, Non-Small-Cell Lung

Trial Of CP-751, 871 And Erlotinib In Refractory Lung Cancer

NSCLC
Start date: May 2008
Phase: Phase 3
Study type: Interventional

The objective of this study is to test a clinical benefit of the addition of CP 751,871 to erlotinib therapy in patients with advanced NSCLC of non adenocarcinoma histology. The primary endpoint is Overall Survival (OS).

NCT ID: NCT00662740 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

Tiotropium/Salmeterol Inhalation Powder (Spiriva Handihaler and Salmeterol Polyethylene (PE) Capsule) in Chronic Obstructive Pulmonary Disease (COPD)

Start date: April 15, 2008
Phase: Phase 3
Study type: Interventional

The primary objectives of this study are to assess bronchodilator efficacy as determined by forced expiratory volume in one second (FEV1), the effect on dyspnoea as determined by the Baseline Dyspnoea Index/Transition Dyspnoea Index (BDI/TDI), the effect on health status as determined by the St George Respiratory Questionnaire (SGRQ) and the effect on chronic obstructive pulmonary disease (COPD) exacerbations.

NCT ID: NCT00662597 Terminated - Clinical trials for Non-Small Cell Lung Cancer

ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer

ATRACT-1
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if adding ASA404 to standard chemotherapy makes the cancer treatment more effective in patients with advanced lung cancer.

NCT ID: NCT00661011 Terminated - Clinical trials for Non Small Cell Lung Carcinoma

Lobectomy and Mediastinal Radiochemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer Responding to Induction Chemotherapy

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if radical radiochemotherapy on the mediastinum after lobectomy can be associated with significant long term survival in patients with initially unresectable stage III NSCLC responding to induction chemotherapy but in which the residual disease is too large to be treated by radiotherapy.

NCT ID: NCT00658645 Terminated - Schizophrenia Clinical Trials

Efficacy of Bifeprunox in Patients With Schizophrenia

Start date: March 2008
Phase: Phase 3
Study type: Interventional

The primary purpose of the study is to evaluate the efficacy of bifeprunox in the maintenance phase of schizophrenia compared to placebo.