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NCT ID: NCT05977062 Active, not recruiting - Cancer Clinical Trials

Optimization of an Online Stepwise Therapeutic Device Based on a Cognitive-behavioral Approach for Cancer Patients With Insomnia

Sleep-4-All-2
Start date: February 25, 2022
Phase: N/A
Study type: Interventional

Determine who can benefit from additional follow-up by a professional and what type of help is most appropriate (need and expectation of patients in terms of support by a health professional)

NCT ID: NCT05975411 Active, not recruiting - Pregnancy Related Clinical Trials

Telemedicine Anesthesia Consultation, Pilot Study in Obstetrics.

CATmedO
Start date: January 11, 2021
Phase:
Study type: Observational

Pilot study in Lower Normandy concerning a total of 90 patients scheduled for a pre-anaesthesia consultation in obstetrics. These parturients who plan to give birth at the maternity hospital of the CHU will be invited to carry out their anesthesia consultation with a view to childbirth either by way of the telemedicine cabin installed in Dozulé, or by way of the telemedicine trolley installed in a center close to their place of residence, or at the CHU de Caen as usual. The validation of the adequacy of the possibilities of telemedicine with the requirements of the anesthesia consultation worked upstream is the main objective of this work, the appreciation of the parturient at this consultation, the appreciation of the consulting and validating professionals will also be collected with the aim of a maximum optimization of this new offer intended for the region.

NCT ID: NCT05964972 Active, not recruiting - Fall Patients Clinical Trials

Impact of an Automatic Alert Device on the Occurrence of Nocturnal Falls in Nursing Home Residents

NOCTUSAFE
Start date: May 17, 2022
Phase:
Study type: Observational

Impact of an automatic alert device on the occurrence of nocturnal falls in nursing home residents Measurement of the number of nocturnal falls between 8 p.m. and 8 a.m. per registered resident in the 6 months preceding use of the device compared with the number of nocturnal falls in the 6 months after installation of the device.

NCT ID: NCT05964322 Active, not recruiting - Pediatric ALL Clinical Trials

Cardiac Rehabilitation of Children and Adolescent With Long QT Syndrome

RYTHMO'FIT
Start date: February 2, 2022
Phase:
Study type: Observational

Children and adolescents with inherited cardiac arrhythmia su ch Long QT Syndrome (LQTS) have lower physical and quality of life than their healthy peers. A multi-component cardiac rehabilitation, including an exercise training program and education program, might counteract those effects. The goal of this pilot study is to evaluate the security, feasibility, and benefits of a cardiac rehabilitation program in children with LQTS aged between 6 to 18 years old. The main question[s] it aims to answer are: - Is center-based cardiac rehabilitation safe and feasible for children with LQTS? - Does a 12-week cardiac rehabilitation program improve physical fitness and quality of life?

NCT ID: NCT05961826 Active, not recruiting - Clinical trials for Low Phospholipid Associated Cholelithiasis

COLPAC (RaDiCo Cohort) (RaDiCo-COLPAC)

COLPAC
Start date: November 6, 2017
Phase:
Study type: Observational

The goal of this observational study is to describe the various clinical, biological and radiological manifestations of LPAC syndrome, defined according to standard diagnostic criteria, or according to criteria extended to all symptomatic recurrent biliary lithiasis, and delineate the various possible evolutions. Participants will be followed for 5 years and the inclusion sites will collect the necessary data at least once a year as part of routine patient care. A quality of life self-questionnaire will be completed by participants during these visits.

NCT ID: NCT05955963 Active, not recruiting - Crohn Disease Clinical Trials

Bowel Sounds Analysis in Paediatric Inflammatory Bowel Disease: Relationship With wPCDAI

SONO-MICI
Start date: June 24, 2021
Phase: N/A
Study type: Interventional

The precise and noninvasive evaluation of disease activity among patients with Crohn's disease is not easy, especially for children. It deals with clinical, biological, histological and radiological parameters. Bowel sounds (BS) when evaluated by a stethoscope are modified by several factors including surgery, infection, drugs or intestinal inflammation. These factors can interact on intestinal motricity. There is a direct relationship between gastrointestinal motility and characteristics of BW. The study of BS using a stethoscope is a simple method, although operator dependent and subjective,with a wide inter and intraindividual variability. Some studies among adults showed interest in the spectral analysis of BS to assess gastrointestinal motility. This more precise and reproducible method is not operator dependent. To date, no such study has evaluated the correlation between disease activity and the spectral pattern of BS. of this project is to assess the correlation between disease activity and the spectral pattern of BS in pediatric Crohn's disease.

NCT ID: NCT05953974 Active, not recruiting - Clinical trials for Autoimmune Encephalitis

Validation of a Diagnostic Score for Encephalitis to Assess the Risk of Autoimmune Origin

Val-Dia score
Start date: February 1, 2023
Phase:
Study type: Observational

The investigators wish to test a diagnostic risk score for autoimmune encephalitis in case of encephalitis, previously validated by two American teams, in a retrospective analysis, according to the clinical and paraclinical data available in our database of the Reference Centre for Autoimmune Encephalitis and Paraneoplastic Neurological Syndromes of Professor Honnorat for patients with NMDAr, anti LGi1, anti CASPR2, anti GABAbr and anti GAD antibodies.

NCT ID: NCT05949853 Active, not recruiting - Clinical trials for Sleep Apnea, Obstructive

Enhanced Respiratory Polygraphy in Suspected OSA

PVa
Start date: January 1, 2023
Phase:
Study type: Observational

Obstructive Sleep Apnea (OSA) remains underdiagnosed in 2022, as a result of the unawareness of its serious health-related consequences and the lack of diagnosis accessibility. Respiratory polygraphy (PV) is widely used as a screening tool and sometimes a diagnosis test, although polysomnography (PSG) remains the gold standard investigation as it provides complete information about sleep architecture and arousals. Thus, it has been shown that the Apnea Hypopnea Index (AHI) and Respiratory Disorder Index (RDI) are underestimated by PV vs PSG. Approaches to substitute PSG by simpler but equally efficient diagnosis tests have included devices aiming to record complementary signals and to analyze them with Artificial Intelligence. In this context, ASEEGA algorithm has demonstrated its performance for automatic sleep scoring in healthy individuals and patients with various sleep disorders, based on a single channel EEG analysis. This study aims at comparing the real-life performance and feasibility of added single channel EEG automatic sleep scoring using ASEEGA to PV versus standard PV and PSG in adults referred to a regional sleep reference center for suspected OSA. We hypothesize that this approach (1) is as accurate as PSG and more accurate that PV for AHI analysis, and (2) is less time-consuming than PSG.

NCT ID: NCT05944835 Active, not recruiting - Surgery Clinical Trials

Validation of Numerical Simulation to Predict Proximal Deployment of Standard Stents

ProxSim
Start date: February 15, 2023
Phase:
Study type: Observational

Endoprosthesis treatment of aortic pathologies has become the reference in the vast majority of situations. The success of this treatment is conditioned by the choice of the endoprosthesis which must be as adapted as possible to the anatomy. This choice is currently based on manual geometric measurements performed on the preoperative scanner using conventional image processing software. The morphological result of the implantation of the endoprosthesis in the aorta is obtained by a CT scan carried out postoperatively. This scanner makes it possible to define the positioning of the endoprosthesis, the apposition surfaces between the aorta and the endoprosthesis and to predict the long-term result.

NCT ID: NCT05944822 Active, not recruiting - Clinical trials for Inflammatory Disease

Pro-inflammatory Cytokines in Case of Essure®

ESCYTO
Start date: November 1, 2022
Phase:
Study type: Observational

It is estimated that 750,000 women (including 200,000 French) have benefited from permanent sterilization by ESSURE® contraceptive implant. The observation in some of these patients of gynecological and extra-gynecological symptoms leads to the surgical removal of these implants. The pathophysiological mechanism(s) is (are) not yet determined. Several pathophysiological hypotheses have been proposed, in particular the inflammatory hypothesis. The investigators propose to study markers of inflammation (pro-inflammatory cytokines) in peritoneal fluid and blood. Cytokines are involved in the physiopathology of autoimmune diseases, infectious pathologies, or even cancer; they are used in everyday practice and can constitute a therapeutic target. Based on the literature which finds a high concentration of cytokines in cases of endometriosis, and a low concentration in healthy control patients, the investigators want to assess inflammation in patients with Essure® implants. The demonstration of one or more specifically increased cytokines in the Essure® group could validate the inflammatory hypothesis and lead to the implementation of specific treatments and relevant markers.