Inflammatory Disease Clinical Trial
Official title:
Study of Pro-inflammatory Cytokines in Case of Essure® Contraceptive Implants
It is estimated that 750,000 women (including 200,000 French) have benefited from permanent sterilization by ESSURE® contraceptive implant. The observation in some of these patients of gynecological and extra-gynecological symptoms leads to the surgical removal of these implants. The pathophysiological mechanism(s) is (are) not yet determined. Several pathophysiological hypotheses have been proposed, in particular the inflammatory hypothesis. The investigators propose to study markers of inflammation (pro-inflammatory cytokines) in peritoneal fluid and blood. Cytokines are involved in the physiopathology of autoimmune diseases, infectious pathologies, or even cancer; they are used in everyday practice and can constitute a therapeutic target. Based on the literature which finds a high concentration of cytokines in cases of endometriosis, and a low concentration in healthy control patients, the investigators want to assess inflammation in patients with Essure® implants. The demonstration of one or more specifically increased cytokines in the Essure® group could validate the inflammatory hypothesis and lead to the implementation of specific treatments and relevant markers.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03964324 -
NO Measurements in Screening for Asthma and OSA, in Patients With Severe Snoring
|
N/A | |
| Recruiting |
NCT03963648 -
NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP
|
N/A | |
| Not yet recruiting |
NCT04997343 -
Neurophysiological Assessment in Patients With Multiple Sclerosis
|
N/A | |
| Completed |
NCT01695876 -
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food Effect of AMG 357 in Healthy Subjects
|
Phase 1 | |
| Not yet recruiting |
NCT05546788 -
Hydroxylated Polymethoxy Flavones Solid Dispersion in Treatment of Periodontitis
|
Phase 1 | |
| Recruiting |
NCT03651518 -
Personalized Therapies in Inflammatory Complex Disease
|
Phase 2 | |
| Not yet recruiting |
NCT05544448 -
In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory Diseases
|
N/A | |
| Completed |
NCT02552004 -
Assessment of Intraoperative Probe-based Confocal Laser Endomicroscopy in Digestive and Endocrine Surgery: a Pilot Study
|
N/A | |
| Completed |
NCT04368494 -
Exercise Therapy in Patients With Axial Spondyloarthritis
|
N/A | |
| Completed |
NCT03878134 -
Translational Development of Photon-counting CT Imaging
|
N/A | |
| Recruiting |
NCT06059989 -
inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease
|
Phase 3 | |
| Completed |
NCT02959138 -
Pharmacokinetics of Lanraplenib in Adults With Impaired Renal Function
|
Phase 1 | |
| Recruiting |
NCT04565821 -
Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe
|
N/A | |
| Recruiting |
NCT05509075 -
Nutraceuticals and Functional Foods
|
||
| Completed |
NCT05115370 -
Vaccination Perception in Inflammatory Conditions - Flu, Pneumonia and COVID-19
|
||
| Active, not recruiting |
NCT03604406 -
The Immunogenicity and Safety of Zostavax® and Shingrix® in Rheumatoid Arthritis Patients Using Abatacept
|
Phase 2 | |
| Completed |
NCT05022017 -
Description of Statics by EOS Imaging and Evaluation of the Efficacy of Intradiscal Corticosteroid Infiltration
|
||
| Recruiting |
NCT05364294 -
Molecular Diagnosis of Systemic Autoinflammatory Diseases
|
||
| Recruiting |
NCT05860400 -
Efficacy and Safety of Comprehensive Treatment in Patients With IR-CAD: a Self-controlled Cohort Study
|
||
| Completed |
NCT02084147 -
PET-MRI in Diagnosing Patients With Cancer, Cardiac Diseases, or Neurologic Diseases
|
N/A |