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NCT ID: NCT02387996 Completed - Clinical trials for Various Advanced Cancer

A Study of Nivolumab in Participants With Metastatic or Unresectable Bladder Cancer

Start date: March 9, 2015
Phase: Phase 2
Study type: Interventional

The purpose the study is to measure the effect of nivolumab (BMS-936558) in reducing tumor size in subjects with metastatic or unresectable bladder cancer.

NCT ID: NCT02383745 Completed - Status Epilepticus Clinical Trials

EEG in In-hospital Patients With Seizure or Altered Mental State

Start date: December 1, 2014
Phase:
Study type: Observational

In Kuopio University Department of Clinical Neurophysiology there have been designed a fast EEG electrode, that is suitable for acute emergency use. It is easy to set up, records high quality EEG and can detect the most important EEG abnormalities comparable to conventional EEG. This study will address the clinical use of acute EEG with fast electrode set in in-hospital patients who have been consulted by Medical Emergency Team because of seizure or altered mental state of uncertain etiology. Patients are going to be treated in ICU and EEG monitoring will continue for 24 hours.

NCT ID: NCT02380651 Completed - Cancer of Muscle Clinical Trials

Functional Outcomes and HRQoL in Upper-extremity Sarcoma Patients After Limb Salvage

Start date: December 2015
Phase:
Study type: Observational

This study aims to assess the functional ability and health-related quality of life (HRQoL) of upper extremity sarcoma patients who have undergone limb salvage surgery.

NCT ID: NCT02377960 Completed - Hypertension Clinical Trials

Check and Support -Enhancing the Treatment of Hypertension in Outpatient Care, a Multicenter Study

Start date: January 27, 2015
Phase: N/A
Study type: Interventional

The purpose of this pragmatic multi-centre, cluster randomized controlled trial is to test the effectiveness of tailored SMS-text message support combined with an information-motivation-behavioral skills (IMB) model-based initiation of medication in helping outpatient care patients with hypertension to achieve blood pressure target and to enhance medication adherence.

NCT ID: NCT02377349 Completed - Clinical trials for Diphtheria-Tetanus-acellular Pertussis Vaccines

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Pregnant Women

Start date: October 14, 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the immunogenicity and safety of Boostrix™ when compared to a placebo given during 27-36 weeks of gestation in healthy women aged 18-45 years. Infants born to mothers enrolled in this study will be followed-up in two separate clinical studies: 201330 [DTPA (BOOSTRIX)-048 PRI] and 201334 [DTPA (BOOSTRIX)-049 BST: 048].

NCT ID: NCT02372825 Completed - Limb Salvage Clinical Trials

Role of Free Iliac Crest Flap in Heel and Ankle Reconstruction

Start date: June 2014
Phase: N/A
Study type: Observational [Patient Registry]

Treatment of extensive traumatic acute bone defects or sequela in heel or ankle poses a formidable challenge for the reconstructive surgeon. These defects can be treated with the vascularized iliac crest transfer. The purpose of this study is to assess the reliability and the long-term outcomes of free iliac crest flap transfer for these indications.

NCT ID: NCT02371629 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

A Study of the Efficacy and Safety of NVA237 in Patients With Moderate to Severe COPD

Start date: June 24, 2015
Phase: Phase 4
Study type: Interventional

This study is a post-authorization commitment to the European Medicines Agency (EMA). The study serves to determine whether the treatment of patients with stable, symptomatic Chronic Obstructive Pulmonary Disease (COPD) with the investigational drug NVA237 is efficient and safe. The efficacy and safety of the drug was tested for twice daily dosing against once daily dosing.

NCT ID: NCT02369991 Completed - Clinical trials for Reconstructive Surgical Procedure

Treatment of Compound Tibia Fracture With a Microvascular Latissimus Dorsi Flap and the Ilizarov Technique

Start date: June 2014
Phase: N/A
Study type: Observational [Patient Registry]

This study assesses the long-term results of compound tibial reconstruction treated with a microvascular latissimus dorsi flap and bone transport technique during the last 25 year in Helsinki University central Hospital.

NCT ID: NCT02367573 Completed - Hernia, Inguinal Clinical Trials

3D vs 2D HD Laparoscopy in Inguinal Hernia Repair

Start date: January 2015
Phase: N/A
Study type: Interventional

Inguinal hernia can be repaired laparoscopically. In the normal laparoscopy there are only two-dimensional view, which is somewhat challenging when operating in three-dimensional environment. The three-dimensional laparoscopic systems are gradually entering the operating rooms. There are plenty of evidence of the benefits of 3D-system in laboratory conditions. However, no prospective randomized trials have been published in the clinical point of view. Therefore, the purpose of this study is to investigate is there something to gain in changing into 3D laparoscopic system in the transabdominal pre-peritoneal (TAPP) inguinal hernia repair.

NCT ID: NCT02364973 Completed - IBD Clinical Trials

Combined PET-MRI in the Diagnostics of Chronic Inflammatory Bowel Diseases (IBD)- a Feasibility Study

Start date: November 2014
Phase:
Study type: Observational

The main purpose of the present study is to examine the diagnostic performance of combined PET-MRI in detecting colonic and small bowel wall inflammatory processes caused by ulcerative colitis and Crohn's disease.