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NCT ID: NCT04961879 Active, not recruiting - Finger Injuries Clinical Trials

Dorsal Finger Reconstruction

Start date: July 14, 2021
Phase: N/A
Study type: Interventional

objective of this study is To compare reversed cross finger flap with reversed island homo-digital flap in distal dorsal finger defect reconstruction regarding reliability & functional and aesthetic outcomes . comparative study that will be conducted at Plastic surgery department, Sohag university hospital on 30 patients .The population of the study will be patients with distal dorsal digital defects. We will divide the cases into two equal groups: the first are operated with reversed cross-finger flap and the second are operated with reversed island homo-digital flap.

NCT ID: NCT04952350 Active, not recruiting - Covid19 Clinical Trials

Atorvastatin for Reduction of 28-day Mortality in COVID-19: RCT

COVID-STAT
Start date: August 14, 2021
Phase: Phase 3
Study type: Interventional

This randomized placebo-controlled double-blinded clinical trial aims to test the efficacy of administering atorvastatin 40 mg to hospitalized COVID-19 patients for 28 days on the all-cause 28-day mortality.

NCT ID: NCT04945564 Active, not recruiting - Covid19 Clinical Trials

Covid-19 Patients Management During Home Isolation

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The study will investigate management of Covid-19 patients in home isolation.

NCT ID: NCT04935879 Active, not recruiting - Sickle Cell Disease Clinical Trials

A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises

Start date: October 26, 2021
Phase: Phase 3
Study type: Interventional

This Phase 3 study will assess the safety and efficacy of inclacumab, a P-selectin inhibitor, in reducing the frequency of vaso-occlusive crises (VOCs) in approximately 240 adult and adolescent participants (≥ 12 years of age) with sickle cell disease (SCD). Participants will be randomized to receive inclacumab or placebo.

NCT ID: NCT04926389 Active, not recruiting - Malocclusion Clinical Trials

Two Low-level Laser Irradiation Protocols on the Rate of Canine Retraction

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Several methods aiming at the acceleration of orthodontic tooth movement have been proposed, including low-level laser therapy (LLLT), which showed promising results. However, the frequency of patient recall has been one of its major drawbacks.

NCT ID: NCT04903743 Active, not recruiting - Diabetic Patient Clinical Trials

POPLITEAL SCIATIC NERVE BLOCK FOR DIABETIC FOOT SURGERIES

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

Popliteal Sciatic nerve block is a regional technique that provides safe and reliable perioperative anesthesia and analgesia of lower leg and foot used in diabetic patients. Different additives have been used with local anaesthetics to achieve dense and prolonged block. Magnesium sulfate possesses analgesic properties owing to its effect on NMDA receptors.

NCT ID: NCT04902456 Active, not recruiting - Clinical trials for Bimaxillary Protrusion

Evaluation of the Anchorage Loss During En-masse Retraction in Orthodontic Patients With Maxillary Protrusion

Start date: December 29, 2020
Phase: N/A
Study type: Interventional

There is scarcity in literature regarding the effectiveness of friction and frictionless mechanics during ''En-masse retraction''technique on anchorage loss of posterior segment in orthodontic patients with maxillary protrusion. Moreover there is deficiency in studies measuring the patient pain and satisfaction regarding the different techniques of retraction. The aim of the current study is to evaluate the effects of friction versus frictionless mechanics, implemented during "En-masse retraction", on anchorage loss. Additionally, assessment of both techniques regarding their rates, effects on root resorption as well as patient satisfaction.

NCT ID: NCT04896762 Active, not recruiting - COVID-19 Clinical Trials

Extrapulmonary Presentations of COVID-19 Patients

Start date: September 1, 2020
Phase:
Study type: Observational

An observational study about the extrapulmonary presentations of COVID-19 patients during the second wave of the pandemic.

NCT ID: NCT04888676 Active, not recruiting - Clinical trials for Dental Caries Class II

Clinical Evaluation of Self- Adhesive Bulk-fill Resin Composite Versus Conventionally Bonded Bulk-fill Resin Composite in Restoration of Proximal Lesions

Start date: June 15, 2021
Phase: N/A
Study type: Interventional

This study will be conducted to evaluate and compare the clinical performance of Self- Adhesive Bulk fill Resin Composite Versus Conventionally Bonded Bulk fill resin composite in Restoration of Proximal Lesions Over a Period of 18 months Follow-up Examination and selection of all patients will be done according to inclusion and exclusion criteria.A Class II cavity will be prepared after local anesthesia has been given as required. Sectional matricing and wedging will be done. Followed by, placement of restorative material according to the randomization sequence,. For the intervention: The sectional matrix will be applied first , followed by filling of cavity with Advanced Self- Adhesive bulk-fill Resin Composite. (Surefil one™ ,Dentsupply Sirona) in increments of 3-4mm,For the control group: The sectional matrix will be applied first , followed by filling of cavity with bulk-fill resin composite material (GrandioSO x-tra® bulk) in increments of 3-4mm,Clinical evaluation will be done using using USPHS criteria at 6,12 and 18 months follow up.

NCT ID: NCT04884022 Active, not recruiting - Malocclusion Clinical Trials

Effectiveness of Two Skeletally Anchored Force Mechanics for Skeletal Class II Correction in Growing Patients

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

Patients with skeletal Class II malocclusion due to mandibular retrognathism will be recruited and randomly allocated to three equal groups. first group will be treated by pushing orthopedic force mechanics, second group will be treated by pulling orthopedic force mechanics, and third group will be observed for 9 months to detect the natural growth changes. Skeletal changes will be evaluated and the treatment changes will be compared with the natural growth changes. The study hypothesis is that use of direct bimaxillary miniplate anchorage in conjunction with fixed functional appliance (pushing orthopedic force) or closed coil spring (pulling orthopedic force) will induce statistically significant skeletal mandibular growth in comparison to natural mandibular growth changes.