Clinical Trials Logo

Filter by:
NCT ID: NCT06359886 Recruiting - Clinical trials for Blood Loss, Surgical

B-lynch Transverse Compression Suture

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

Is B-Lynch transverse compression suture safe and effective in controlling excessive blood loss during conservative management of women with placenta previa?

NCT ID: NCT06358937 Recruiting - Clinical trials for Periodontal Diseases

Clinical and Microbiological Evaluation of Laser Assisted New Attachment Procedure (LANAP) Using Nd:Yag vs. Diode Laser in the Management Of Stage II Periodontitis

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The aim of the present study is to compare the efficacy of LANAP to conventional scaling and root planing in the management of stage II periodontitis.

NCT ID: NCT06358313 Recruiting - Ischemic Stroke Clinical Trials

Concomitant Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Minor Stroke or TIA

Start date: April 10, 2024
Phase: Phase 3
Study type: Interventional

Along with the current clinical trial, the impact of adding atorvastatin or rosuvastatin in the first 24 hours on the clinical outcomes of first-ever minor stroke or TIA patients treated with clopidogrel and aspirin assessed through NIHSS, mRS, and possible adverse effects.

NCT ID: NCT06358131 Recruiting - Clinical trials for Gastrointestinal Diseases

Propofol Versus Midazolam in Sedation for Upper and Lower Gastrointestinal Endoscopy.

Start date: January 1, 2022
Phase: Phase 1
Study type: Interventional

There has been rapid growth in the number and complexity of gastrointestinal (GI) endoscopic procedures performed during the last decade. To ensure safe and effective upper GI endoscopy, the choice of an appropriate sedative agent is crucial. Sedation usually categorized into four stages: minimal, moderate, deep and general anesthesia. The upper gastrointestinal [GI] endoscopy usually performed under moderate sedation Sedation usually categorized into four stages: minimal, moderate, deep and general anesthesia. The upper gastrointestinal [GI] endoscopy usually performed under moderate sedation. Benzodiazepines still the most common sedative agents used for conscious sedation, either solely or in combination with opioids for upper GI endoscopy. Propofol is a hypnotic drug used for induction of anesthesia with short half-life that permits rapid patient recovery and discharge. Thus, its use is for upper GI endoscopy was adopted in many endoscopy centers. So we are going to Evaluate all adverse events related to anesthesia; in patients recruited for upper and lower endoscopy and compare between propofol and midazolam based anesthesia associated adverse events.Also we are going to Evaluate patient and endoscopist satisfaction as regarding propofol and midazolam anesthesia.

NCT ID: NCT06356792 Recruiting - Clinical trials for Recurrent Miscarriage

Obstetrics , Prenatal Outcomes in Recurrent Miscarriage

OBPORPL
Start date: April 21, 2024
Phase:
Study type: Observational

The effect of recurrent miscarriage on the outcome of the current pregnancy and if there's a relation between it and adverse out come

NCT ID: NCT06354712 Recruiting - Clinical trials for Oral Mucositis (Ulcerative) Due to Radiation

Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients.

Start date: April 4, 2024
Phase: Phase 2
Study type: Interventional

A prospective, randomized, controlled, parallel clinical trial will be conducted at Clinical Oncology and Nuclear Medicine Center at Mansoura University Hospital to assess the efficacy of N-acetylcysteine in the prevention of radiotherapy induced oral mucositis in Head and Neck cancer patients.

NCT ID: NCT06354374 Recruiting - Soft Tissue Volume Clinical Trials

Soft Tissue Volume, Dimensions and Tomographic Alveolar Ridge Classification System for Dental Implant Treatment.

Start date: February 22, 2024
Phase:
Study type: Observational

Despite the importance of soft tissue dimensions for periodontal, restorative, implant, and orthodontic treatment, the current classifications of tomographic alveolar ridge topography lack the soft tissue component(Tolstunov, 2014). Therefore, the present study will be to evaluate the relationship between soft tissue volume and the dimensions & tomographic alveolar ridge classes as well as to incorporate the soft tissue volumetric evaluation in the classification system.

NCT ID: NCT06353048 Recruiting - Clinical trials for Tibial Plateau Fractures Schatzker Type II

Short Term Radiological and Clinical Outcomes of Fixation of Schatzker II Tibial Plateau Fractures by Screws Only Versus Plate and Screws , Comparative Study

Start date: February 10, 2024
Phase: N/A
Study type: Interventional

Tibial plateau fractures are complex injuries produced by high- or low-energy trauma. They principally affect young adults or the 'third age' population ,the tibial plateau is a major weight-bearing surface within the largest and most kinematically complex joint in the human body. Fractures occur as a result of a combination of an axial loading force and a coronal plane (varus/valgus) moment leading to articular shear and depression and mechanical axis malalignment,So Limb alignment and articular surface restoration, allowing early knee motion, are the main goals of surgical treatment. Soft-tissue damage in fractures around the knee is of critical importance. The oedema and inflammation associated with the trauma can easily lead to local venous compromise, dermal hypoxia, and additional soft-tissue injury. This commonly leads to blistering of the skin and in some cases dermal and even muscle necrosis. Blood-filled blisters should be expected to be associated with a worse outcome than clear fluid-filled ones. Management in the early stages of treatment should focus on preventing further soft-tissue injury while waiting to repair the fracture. Traditionally, initial radiograph diagnosis should include anteroposterior (AP), lateral and oblique views. But single radiographs do not allow an exact fragment identification and the initial fracture classification can change in 5% to 24% (mean 12%) of cases and treatment can change in up to 26% of cases after CT scan imaging . These findings and the wider availability of CT scanning have made the oblique views less important in the diagnosis. Intra- and peri-articular soft-tissue structures can be affected even in less complex fracture patterns and some X-ray or CT scan data can also suggest the existence of a lateral or medial meniscal tear. Articular depression > 6 mm and/or articular widening > 5 mm are associated with the existence of lateral meniscus, lateral collateral ligament (LCL) or posterior cruciate ligament injuries . Schatzer classification (published in 1974) will be used to complete understanding of the personality of these fracture which is the key element in decision making process when choosing the best possible treatment . In general ,tibial plateau fracture are to be operated on , but the decision whether to be operated or not on a specific fracture should be based on the fracture morphology ,soft tissues , the patient general condition and the expected limb axis and articular surface restoration. Usual indications for surgical treatment are : 1. Intra-articular displacement of ⩾ 2 mm 2. Metaphyseal -diaphyseal translation > 1 cm 3. Angular deformity more than 10 degree in the coronal or sagittal view 4. Open fracture , compartment syndrome and associated ligament injury require repair. 5. Associated fractures of the ipsilateral tibia or fibula Frequently the depressed articular fragments have to elevated back toward the knee , followed by fixation and sometimes supplemented with bone graft to fill any cancellous bone voids left beneath the joint surface after fracture reduction . We will evaluate treatment outcomes of closed reduction and percutaneous cannulated screw fixation for tibial plateau fractures versus open reduction and fixation by plate

NCT ID: NCT06352606 Recruiting - General Anesthesia Clinical Trials

Spinal and General Anesthesia in Neonates Undergoing Herniorrhaphy

Start date: April 6, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to compare spinal and general anesthesia in neonates undergoing herniorrhaphy.

NCT ID: NCT06352593 Recruiting - Dexmedetomidine Clinical Trials

Intraoperative Dexmedetomidine Infusion in Endovascular Intervention for Aneurysmal Subarachnoid Hemorrhage

Start date: April 6, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the role of intraoperative dexmedetomidine infusion in endovascular intervention for aneurysmal subarachnoid hemorrhage.