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NCT ID: NCT05813834 Active, not recruiting - Clinical trials for Genicular Nerve Block for Pain in ACL Arthroscopy

Ultrasound-guided Genicular Nerves Block

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Most of arthroscopic ACL repairs are day case surgeries associated with moderate postoperative pain and discomfort. So , finding an effective and safe, analgesic technique with minimal complications is our goal for fast recovery and short hospital stay. in this study, we aim to compare the efficacy of genicular nerve block against controls on postoperative pain scores, the need for rescue analgesics, patient's satisfaction and range of motion (ROM) after arthroscopic ACL cases.

NCT ID: NCT05810662 Active, not recruiting - Clinical trials for Fluid and Electrolyte Imbalance

RL Versus Glucose Saline in Cancer Patient Undergoing Major Surgeries and Its Impact on Electrolytes, GLC & pH

Start date: September 4, 2022
Phase: N/A
Study type: Interventional

To compare two electrolytes maintenance in perioperative period in children undergoing major surgeries on perioperative change in pH,lactate,sodium and glucose level

NCT ID: NCT05808465 Active, not recruiting - Clinical trials for Valvular Heart Disease Stenosis and Regurgitation

Different Methods of Cardiac MRI in Assessment of Estimated Corrected Ejection Fraction in Valvular Heart Diseases

Start date: March 10, 2023
Phase:
Study type: Observational

Comparative study between Phase Contrast , Modified Simpson Rule and Myocardial Strain Analysis methods of Cardiac Magnetic Resonance Imaging in assessment of Corrected Estimated Ejection Fraction in Valvular Heart Disease To Evaluate the diagnostic accuracy of different methods of cardiac MRI to assess estimated corrected ejection fraction in valvular heart diseases.

NCT ID: NCT05807711 Active, not recruiting - Clinical trials for End Stage Renal Disease

Efficacy of L-methylfolate and Methylcobalamine in Treating Hypertension and Its Impact on Serum Homocysteine in Hemodialysis Patients With Resistant Hypertension

Start date: April 1, 2023
Phase: Phase 4
Study type: Interventional

The aim of the study is to evaluate the efficacy of L-methylfolate in combination with methylcobalamine in reducing homocysteine blood levels in hypertensive end-stage renal disease patients on regular hemodialysis and its association with blood pressure control in treatment of resistant hypertension

NCT ID: NCT05806229 Active, not recruiting - Clinical trials for Regional Anesthesia for Postnephrectomy Pain

Ultrasound- Guided Mid Point Transverse Process to Pleura Block

Start date: July 30, 2022
Phase: N/A
Study type: Interventional

Radical nephrectomy is the surgical process for the resection of malignant tumors of the kidney necessitating a subcostal flank incision.Mild to severe pain is observed in the postoperative period Ineffective pain management leads to several complications. The mid point transverse process to pleura block (MTP) , this technique was used for pain relief after mastectomy, thoracic, abdominal, and spinal surgery and was found effective due to its simplicity and lower risks compared to epidural analgesia.

NCT ID: NCT05802979 Active, not recruiting - Post Operative Pain Clinical Trials

Ketamine Versus Neostigmine as Adjuvants to Bupivacaine During Ultrasound-guided Serratus Anterior Block

Start date: January 1, 2023
Phase: Phase 3
Study type: Interventional

This study is designed to investigate the analgesic efficacy of ketamine compared to neostigmine as adjuvants to LA in ultrasound guided Serratus Anterior Plane Block (SAPB) in patients undergoing Modified Radical Mastectomy. We hypothesize that adding either neostigmine or ketamine to bupivacaine in ultrasound guided SAPB would increase the total analgesic duration and decrease the total 24 hr postoperative Nalbuphine consumption compared to SAPB with bupivacaine only. The first 24 hr of postoperative Nalbuphine consumption is set as the primary outcome. The time of the first request of analgesia, pain score, side effects of drugs and patient hemodynamics are set as the secondary outcomes.

NCT ID: NCT05794685 Active, not recruiting - Clinical trials for Comparing the Analgesic Outcome by ( 4 in 1 Block ) & ( Adductor Canal Block )

The Analgesic Efficacy of Ultrasound Guided Adductor Canal Block Versus 4 in 1 Block in Patients Undergoing Knee Surgeries: A Comparative Randomized Double Blinded Study .

No acronym
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Knee surgeries are associated with severe postoperative pain. Improper pain management affects patients' psychological status with prolongation of hospital stay time and rehabilitation period, with the possibility of progression of the acute pain to chronic pain (McCartney CJ, Nelligan K., 2014). Many Pain management options following these surgeries are available: non-opioid analgesics, opioids and regional anesthesia techniques (epidural and peripheral nerve block). Multi-modal analgesia is considered the best option for pain management in knee surgeries. As non-opioid analgesics alone are not effective enough while opioids alone are associated with many risk factors: nausea, vomiting, decrease intestinal motility and respiratory depression with possibility of addiction (Goode VM, Morgan B, et al, 2019)

NCT ID: NCT05792501 Active, not recruiting - Clinical trials for Ventilator Associated Pneumonia (VAP)

Pulmonary Infections and Barotrauma Associated With MV IN PICU

Start date: April 1, 2022
Phase:
Study type: Observational

This study aims to determine the incidence, risk factors and outcome of ventilation associated common complication in the PICUs at Assiut University Children Hospital in Egypt.

NCT ID: NCT05787769 Active, not recruiting - Clinical trials for Erectile Dysfunction Following Radiation Therapy

A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of intracavernosal injection of PRP in patients with moderate to severe ED.

NCT ID: NCT05782946 Active, not recruiting - Smoking and POCD Clinical Trials

The Effect of Heavy Smoking on Early Post Operative Cognitive Dysfunction in Senile Patients .

Start date: April 1, 2023
Phase:
Study type: Observational

Cognitive dysfunction is the impairment of mental process of perception, memory and information processing which allow the human to acquire knowledge and plan for the future . The etiology of Postoperative cognitive dysfunction (POCD) is unclear and seems to be multifactorial involving a combination of patient, surgical, anesthetic and environmental factors .It can be a manifestation of transient or permanent cerebral injury. While cognitive function tends to improve over months to years postoperatively in affected individuals, some proportion has seemingly permanent cognitive injury .