Clinical Trials Logo

Filter by:
  • Completed  
  • Page [1] ·  Next »
NCT ID: NCT06413901 Completed - Hypospadias Repair Clinical Trials

TIP Repair of Distal Penile Hypospadias Using Rapidly Absorbable Braided Vs Slowly Absorbable Monofilament Sutures

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Objective: To study the effect of tubularizing the urethral plate in DPH in children using 2 different absorbable suture materials, rapidly absorbable, braided 6/0 Vicryl and slowly absorbable monofilament 6/0 Polydioxanone, on complication rates. Patients and methods: A prospective, randomized controlled study conducted at the Urology Department, Cairo University Specialized Pediatric Hospital, Abou El Reesh, between September 2021 and September 2022. A total of 69 boys aged between 8 and 120 months with DPH were randomly divided into 2 groups: group(A) Vicryl included 39 boys and group(B) PDS included 30 boys. All boys were uncircumcised with no chordee and were primary repairs. TIP was the surgical technique used by a single pediatric urologist. Follow up was performed in outpatient clinic at 7 days, 1, 3, 6 and 12 months postoperatively. The complications and reoperation rates for both groups were compared.

NCT ID: NCT06413628 Completed - Cancer Clinical Trials

Efficiency of Different Treatment Modalities on Radiation Induced Trismus for Maxillofacial Patients

Start date: April 11, 2022
Phase: N/A
Study type: Interventional

Aim: to compare different treatment modalities for radiation induced trismus for maxillofacial patients methods:45 participants (20 females and 25 males) with trismus and pain following head and neck cancer and underwent radiation therapy were enrolled in this study . patients were divided into three groups : group1 received threaded tapered screw appliance therapy, patients in group II received low-level laser therapy and patients in group III received low-level laser therapy in addition to threaded tapered screw appliance therapy.

NCT ID: NCT06413589 Completed - Acute Poisoning Clinical Trials

Efficacy of SMOF Lipid in the Management of Acute Poisoning With Clozapine

Start date: January 1, 2022
Phase: Phase 2
Study type: Interventional

The goal of the current study was to evaluate whether SMOF lipid administration could be used as an adjuvant therapy to treat acute, moderate-to-severe clozapine poisoning.

NCT ID: NCT06413056 Completed - Neonatal Infection Clinical Trials

Micafungin Versus Amphotercine B in Treatment of Invasive Fungal Infection

Start date: October 20, 2022
Phase: Phase 4
Study type: Interventional

The incidence of fungal infection has increased dramatically over the past few decades.This is due to increase in survival rates of preterm neonates, advances in medical technology and drug therapy, broad spectrum antibiotics and parenteral nutrition . The resistance to antifungal agents has increased. This study will assess the efficacy of micafungin versus amphotericin B in neonates with positive fungal culture.

NCT ID: NCT06412159 Completed - Denture Clinical Trials

Digital Evaluation of Accuracy for Removable Partial Denture Frameworks

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Purpose: To compare the overall accuracy and fit of different components for mandibular metallic removable partial denture (RPD) frameworks fabricated by selective laser melting using combined analog-digital, and fully digital impression techniques. Material and methods. Two RPD frameworks were fabricated for each of the 18 participants using each of the 2 techniques of the 18 participants enrolled, were of mandibular Kennedy class I, the first technique was the combined analog-digital workflow had the analog steps include: a physical impression was made using polyvinyl siloxane, stone casts were made, then the stone cast was scanned with a laboratory scanner to generate a digital cast. The 3Shape CAD software was then used to design a digital RPD, which was fabricated from a cobalt-chroumum alloy by selective laser melting. The second technique was fully digital where an intraoral digital scanner was used to make a definitive scan, which was sent to the 3Shape software for digitally designing the RPD framework and subsequent selective laser melting for fabrication. For both frameworks in the same participant, the same design was used for consistency. To assess the accuracy of fit, based on STL data analysis (intra-oral digital superimposition evaluation), a color map was constructed using non metrology software, and overall fit accuracy and the misfit (distance between each framework component and the reference intra-oral scan) were measured at rest, guiding plane and lingual plate areas.

NCT ID: NCT06409377 Completed - Dexmedetomidine Clinical Trials

Effect of Dexmedetomidine on Improving Intubating Conditions Without the Use of Muscle Relaxant

Start date: February 25, 2024
Phase: Phase 4
Study type: Interventional

Tracheal intubation is usually facilitated by the administration of anesthetic drugs including a muscle relaxant. Over the past few years, several factors have led researchers to consider omitting neuromuscular blocking agents for tracheal intubation. (1, 2) Despite the frequent use of NMBAs in clinical practice, side effects associated with NMBA use can be particularly concerning such as anaphylaxis, cardiovascular effects related to histamine release or sympathomimetic properties, Bronchospasm, and prolonged paralysis. (3) Therefore, many studies (4, 5) focused on the possibility of performing tracheal intubation without the use of neuromuscular blocking agents. The challenge was to find the correct choice and dose of induction agent, opioid, or adjuvant drug to produce adequate intubating conditions without cardiovascular side effects. Dexmedetomidine is a potent and highly selective alpha-2 receptor agonist with sympatholytic, sedative, amnestic, and analgesic properties. It inhibits sympathetic activity thus terminating the pain signals and thereby blunts the pressor response associated with laryngoscopy and endotracheal intubation.

NCT ID: NCT06409104 Completed - Sedation in ERCP Clinical Trials

Propofol Versus Dexmedetomidine for Sedation of Cancer Patients Undergoing ERCP

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy and safety of propofol and dexmedetomidine during ERCP regarding hemodynamic, respiratory, sedative and cognitive functions.

NCT ID: NCT06404918 Completed - Clinical trials for Modified Radical Mastectomy

Preemptive Erector Spinae Plane Block Versus Serratus Anterior Plane Block in MRM

Start date: January 22, 2023
Phase: N/A
Study type: Interventional

Modified radical mastectomy (MRM) is one of the most performed surgeries for breast cancer. MRM is associated with significant pain during the immediate postoperative period.

NCT ID: NCT06404398 Completed - Tooth Discoloration Clinical Trials

Clinical Evaluation of Single Versus Multi-Shade Direct Composite Resin Veneers

Start date: July 19, 2022
Phase: N/A
Study type: Interventional

The aim of this study was to clinically evaluate the single versus multi-shade direct composite resin veneers.

NCT ID: NCT06403488 Completed - Clinical trials for Polycystic Ovary Syndrome

Letrozole Dose Increments in PCOS Patients Resistant to Letrozole

Start date: October 1, 2023
Phase: Phase 3
Study type: Interventional

Objectives: To study the effect of Letrozole dose increments on ovulation rate and endometrial thickness as a primary outcomes in patients with polycystic ovary syndrome who previously resistant to letrazole conventional dose, and chemical and clinical pregnancy considered as secondary outcomes.