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NCT ID: NCT04252716 Completed - Cataract Senile Clinical Trials

VISPER: Randomised Comparison of Two OVDs in Cataract Surgery

VISPER
Start date: September 24, 2020
Phase:
Study type: Observational

To investigate that VISTHESIA 1.5 is non-inferior to Provisc with regards to elevation in IOP greater than or equal to 30 mm Hg 6 ± 2 hours post-operatively as per methodology set out in EN ISO 15798:2013 (Primary Endpoint) To compare the changes in endothelial cell count and incidences of intraocular inflammation between VISTHESIA and Provisc as per methodology set out in EN ISO 15798:2013

NCT ID: NCT04252495 Completed - Healthy Subjects Clinical Trials

The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics

Start date: June 26, 2020
Phase: Phase 1
Study type: Interventional

This is a prospective, open-label, single-dose, Phase 1 study, to assess the effect of moderate hepatic impairment due to liver cirrhosis on the pharmacokinetics of aprocitentan (ACT-132577).

NCT ID: NCT04251936 Completed - Healthy Clinical Trials

Modification of Alternative Reward Cue Reactivity and Cognitive Control Through Physical Activity in Human Tobacco Use Disorder

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

This study investigates the mechanisms, through which physical exercise impacts positively on abstinence in tobacco use disorder, with fMRI and behavioral tests.

NCT ID: NCT04250909 Completed - Overall Mortality Clinical Trials

Retrospective Follow-up of BIOLUX P-I/-II

Start date: February 25, 2020
Phase:
Study type: Observational

The aim is to collect long-term clinical data from 132 patients from Belgium, Germany and Austria who had previously participated in either of the BIOLUX P-I or P-II studies. Patients in these studies were treated with either a percutaneous transluminal angioplasty (PTA) balloon catheter or a drug-coated Passe-18-Lux balloon (DCB). The purpose of Retro-BIOLUX P-I-II is to collect clinical data from patients treated with either Passeo-18 PTA or Passeo-18 Lux DCB to analyze the long-term effects.

NCT ID: NCT04250714 Completed - Atrial Fibrillation Clinical Trials

POLARx Cardiac Cryoablation System Study

POLAR ICE
Start date: August 6, 2020
Phase:
Study type: Observational

This is a Post Market Clinical Follow-up (PMCF) study designed to establish the continued safety and effectiveness profile of the Boston Scientific Cardiac Cryoablation System after receiving CE mark.

NCT ID: NCT04250337 Completed - Atopic Dermatitis Clinical Trials

Safety and Efficacy of Lebrikizumab (LY3650150) in Combination With Topical Corticosteroid in Moderate-to-Severe Atopic Dermatitis.

ADhere
Start date: February 3, 2020
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled, parallel-group study which is 16 weeks in duration. The study is designed to evaluate the safety and efficacy of lebrikizumab when used in combination with topical corticosteroid (TCS) treatment compared with placebo in combination with TCS treatment for moderate-to-severe atopic dermatitis.

NCT ID: NCT04250207 Completed - Clinical trials for Fuchs' Endothelial Corneal Dystrophy

Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis

Start date: June 23, 2020
Phase: Phase 2
Study type: Interventional

The objective of this study is to investigate the effect of K-321 in patients with Fuchs endothelial corneal dystrophy (FECD) after descemetorhexis.

NCT ID: NCT04248673 Completed - Body Weight Clinical Trials

Düsseldorf Bread Study

DBS
Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The hypothesis is to be tested that eating carbohydrate-reduced bread over three months leads to a significant weight difference compared to conventional, carbohydrate-rich bread.

NCT ID: NCT04248140 Completed - Sleep Clinical Trials

Effects of WiFi Exposure on Sleep

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Effects of Wifi exposure on sleep and sleep-related Memory consolidation are investigated in a double-blind, sham-controlled fully counterbalanced study design.

NCT ID: NCT04247737 Completed - Gluten Sensitivity Clinical Trials

Gluten Free Diet in IBS

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Patients with irritable bowel syndrome (IBS) often benefit from dietary changes. The effect of a gluten-free diet (GFD) on clinical symptom improvement and psychological well-being will be checked in patients with IBS. In addition, the stimulatory potential of gluten on peripheral blood monocytes will be determined. Responders will be provoked with gluten containing bars or placebo bars to confirm the diagnosis of non-celiac glutensenstitivity.