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NCT ID: NCT03881059 Not yet recruiting - Clinical trials for Active Psoriatic Arthritis

Efficacy and Safety of BMS-986165 Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA)

Start date: March 29, 2019
Phase: Phase 2
Study type: Interventional

The main purpose of study is to assess the dose-response relationship of BMS-986165 (Dose A or Dose B once daily [QD]) at Week 16 in the treatment of participants with active PsA.

NCT ID: NCT03880851 Recruiting - Prostate Cancer Clinical Trials

MR-based Hypofractionated Adaptive IGRT of Prostate Cancer (M-base HyPro 2.0)

Mbase_HyPro
Start date: January 23, 2019
Phase: N/A
Study type: Interventional

Single-centre single-armed, non-randomized interventional phase II-study of hypofractionated image-guided radiotherapy "IGRT" with weekly magnetic resonance imagings "MRI" for personalized adaptation of the treatment plan depending on individual MR-anatomy of prostate/organ at risks "OAR" during course of IGRT.

NCT ID: NCT03880578 Not yet recruiting - Quality of Life Clinical Trials

Quality of Life After Surgery and Radioiodine Treatment

DSR
Start date: April 1, 2019
Phase:
Study type: Observational

In this study, patients are prospectively followed after surgery or radioiodine treatment to assess the relationship between thyroid status and their quality of life after thyroid ablative treatment.

NCT ID: NCT03880513 Recruiting - Clinical trials for Endogenous Cushing's Syndrome

Cardiovascular Status in Patients With Endogenous Cortisol Excess (Cushing's Syndrome)

CV-CORT-EX
Start date: October 2014
Phase:
Study type: Observational [Patient Registry]

Within this trial, the cardiovascular and mental status as well as the metabolic profiles of patients with endogenous cortisol excess are evaluated.

NCT ID: NCT03879850 Not yet recruiting - Clinical trials for Postoperative Delirium

Perioperative Electroencephalography Characteristics of Postoperative Delirium in Elderly

Start date: April 1, 2019
Phase:
Study type: Observational

The investigators aim to identify preoperative Electroencephalogram (EEG) markers indicating patients at risk to develop postoperative delirium (POD), so that the anesthetist may adjust medications and dosages in order to avoid POD. Second, the investigators aim to specify intraoperative EEG signatures and EEG states that are related to POD and long-term cognitive dysfunction, again to enable physicians to adapt their procedure. Third, the investigators aim to identify EEG signatures during stay in the recovery room that is directly related to POD, and may therefore be used as diagnostic tool, as well as a predictor for the development of long-term cognitive deficits (POCD).

NCT ID: NCT03879668 Not yet recruiting - Advanced Disease Clinical Trials

Monitoring of Palliative Care Needs in Specialized Palliative Home Care Using the Electronic Version of the Integrated Palliative Care Outcome Scale

Palli-MONITOR
Start date: January 1, 2020
Phase:
Study type: Observational

In palliative care, the Integrated Palliative Care Outcome Scale (IPOS) is widely used as a patient reported outcome measure (PROM) and covers patients' main concerns, common symptoms, patient and family distress, existential wellbeing, sharing feelings with family, information received, and practical concerns. The IPOS is validated for patients with advanced cancer or non-cancer disease and is available as patients and professional carer version. The implementation of a PROM in the home care setting is more challenging compared to the inpatient setting. Palli-MONITOR will develop, implement and test the feasibility of an internet-based real-time monitoring of palliative needs of patients with advanced diseases using the electronic version of IPOS (eIPOS) including a clinical decision support tool for specialist palliative home care. The project is conducted in two parts: 1. A pilot study to develop an electronical monitoring that is acceptable for both palliative patients and professionals of specialist palliative home care teams. 2. A feasibility study to implement and test eIPOS in specialist palliative home care teams.

NCT ID: NCT03879512 Recruiting - Clinical trials for Childhood Glioblastoma

Autologous Dendritic Cells and Metronomic Cyclophosphamide for Relapsed High-Grade Gliomas in Children and Adolescents

Start date: February 7, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This phase I/II trials evaluates the feasibility, safety and efficacy of an individualized cancer vaccine, based on autologous, tumor-lysate loaded dendritic cells in children and adolescents with relapsed high-grade gliomas. In addition, regulatory T cells are depleted by a short cycle of metronomic cyclophosphamide upfront of the vaccine in order to facilitate induction of immune responses.

NCT ID: NCT03879434 Not yet recruiting - Rhizarthrosis Clinical Trials

Routine Application of Ostenil® Mini in Patients With Rhizarthrosis

Start date: March 2019
Phase:
Study type: Observational

PMCF study to observe the routine application of Ostenil® Mini in the treatment of pain and restricted mobility in degenerative and traumatic changes of the CMC joint.

NCT ID: NCT03878420 Recruiting - Clinical trials for Dry Age-related Macular Degeneration

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE II)

Start date: February 14, 2019
Phase: N/A
Study type: Interventional

This LIGHTSITE II study is a double-masked, sham-controlled, parallel design, prospective multi-site study for the use of PBM as a treatment for visual impairment in subjects with dry AMD.

NCT ID: NCT03877484 Recruiting - Wound Clinical Trials

Evaluation of the Safety and Effectiveness of ALLEVYN Gentle Border

Start date: March 6, 2019
Phase:
Study type: Observational

The clinical study will evaluate the safety and effectiveness of the ALLEVYN Gentle Border. The study is a post-market clinical follow-up to assess clinical performance and safety of ALLEVYN Gentle Border with new wound contact layer to support performance claims.