Clinical Trials Logo

Filter by:
  • Completed  
  • Page [1] ·  Next »
NCT ID: NCT06462534 Completed - Type 2 Diabetes Clinical Trials

The Band-Frail Study: A Provincial Intervention to Outweigh Diabetes and Frailty in New Brunswick

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to test whether psychological, social, and physical health outcomes of older adults living with type 2 diabetes and frailty are improved when participating in the Band-Frail Program.

NCT ID: NCT06432946 Completed - Spinal Manipulation Clinical Trials

Sensing-glove System in Manual Therapy

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The objective of this clinical trial is to assess manual therapists' attitudes towards using a sensing-glove system for measuring spinal manipulation force and to compare the effectiveness of two interventions in enhancing their attitudes. The primary questions it aims to address are: - Are manual therapists receptive to employing a sensing-glove system to measure the force applied during spinal manipulations on patients? - Can we enhance manual therapists' attitudes towards this system through either a brief informational video demonstration or a supervised practice session with the system? Researchers will compare the impact of a 7-minute informational video to that of a 20-minute supervised practice session to determine if manual therapists' attitudes towards the use of a sensing-glove while treating their patients can be positively influenced. Participants will: - Engage in a single experimental session. - Complete a questionnaire at the beginning of the experimental session. - Undergo one of the two interventions and promptly complete two questionnaires following this intervention. - Undergo the other intervention and promptly complete the same two questionnaires following this intervention.

NCT ID: NCT06411483 Completed - Obesity Clinical Trials

Determining the Physiological Mechanisms Behind the ObeEnd Device on Factors Regulating Appetite

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

In Canada, over 60% of adults are classified as overweight and obese resulting in a public health crisis including increasing health care costs and negatively impacting the well-being of many Canadians. To overcome these barriers, the ObeEnd device, manufactured by WAT Medical Enterprise, is a new and innovative wellness technology that uses electrical pulses to stimulate acupressure point PC6 to help control appetite. PC6 stimulation could potentially modulate appetite and restore gastric dysfunction, which are important factors that contribute to obesity. If PC6 electrostimulation facilitates the normalization of appetite and restoration of gastric dysfunction in those with obesity, then the device could be a potentially helpful aid to weight loss. To measure the change of appetite hormones and enzymes related to appetite regulation after using the ObeEnd device. The investigators hypothesize that, compared to placebo, electrostimulation of PC6 an acupuncture spot on the wrist over a two-week period will result in changes in enterogastic hormones in a direction that decreases appetite. The investigators also hypothesize that these changes will not affect physical activity levels but will correspond to changes in appetite and diet. This study will provide the first evidence of the effects of electrostimulation at PC6 on factors affecting body weight regulation providing insight into the utility of the ObeEnd device for weight control.

NCT ID: NCT06399237 Completed - Clinical trials for Posterior Tibial Tendon Dysfunction

Biomechanical Effects of Three Types of Foot Orthoses in Individuals With Posterior Tibialis Tendon Dysfunction

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Background : Posterior tibialis tendon dysfunction (PTTD) is characterized by a loss of function of the muscle caused by the degeneration of the tendon leading to a flattening of the arch. FOs can be used as a treatment option, but their biomechanical effects are not yet fully understood. The aim of this study was to investigate the effects of three different types of foot orthoses (FOs) on gait biomechanics in individuals suffering from PTTD. Methods : Fourteen individuals were recruited with painful stage 1 or 2 PTTD based on the Johnson and Strom's classification. Quantitative gait analysis of the affected limb was performed in four conditions: shoed condition (Shoe), prefabricated FOs condition (PFO), neutral custom FOs condition (CFO) and five degrees varus (medial wedge) with a 4 mm medial heel skive custom FOs condition (CVFO). A curve analysis, using 1D statistical parametric mapping (SMP), was used to assess differences in lower limb joint motion, joint moments and muscle activity over the stance phase of gait across conditions.

NCT ID: NCT06389214 Completed - Dry Eye Disease Clinical Trials

A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Start date: April 9, 2024
Phase: Phase 3
Study type: Interventional

A Randomized, Double-Masked, Vehicle-Controlled Parallel Group Clinical Trial to Assess Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease

NCT ID: NCT06379620 Completed - Clinical trials for Post COVID-19 Condition

Pilot Open Label Use of the Hi-OXSR for the Treatment of Post COVID-19 Cognitive Dysfunction

Hi-OXSR
Start date: November 29, 2022
Phase: Phase 1
Study type: Interventional

During the worldwide COVID-19 pandemic a large number patients reported different functional complaints one month or later after recovery from the acute infection. This entity had a number of names including "long-COVID" or "post COVID condition". Long-COVID is on the rise and no effective treatment exists yet to improve cognitive function. Recent research has shown that people with even mild COVID had a greater decline in executive function, notably in their ability to perform complex tasks. What drives post-COVID cognitive changes is still a mystery and there are no effective treatments available. One hypothesis is that there is persistent immune activation resulting in reduction in cerebral blood flow. There is evidence that increased CO2 may decrease inflammation, and decreased CO2 may increase inflammation. Objectives: The primary objective of this pilot study is to assess the safety and tolerability of the use of Hi-OX sequential rebreathing for the treatment of post-COVID cognitive dysfunction. The secondary objective is to identify the effects of the use of the Hi-OX rebreathing treatment in changing post-COVID cognitive dysfunction.

NCT ID: NCT06361576 Completed - Clinical trials for Upper Gastrointestinal Cancer

Real-World Use of Nivolumab for the Treatment of Patients With Metastatic Upper Gastrointestinal Cancer in Canada

Start date: September 5, 2023
Phase:
Study type: Observational

The purpose of this observational study is to describe the demographics, and disease characteristics of participants with metastatic upper gastrointestinal cancer, along with the treatment characteristics of these patients when treated with nivolumab.

NCT ID: NCT06361563 Completed - Clinical trials for Upper Gastrointestinal Cancer

Real-World Use of Adjuvant Nivolumab in Patients With Upper Gastrointestinal Cancer in Canada

Start date: September 5, 2023
Phase:
Study type: Observational

The purpose of this observational study is to describe the patient, disease and treatment characteristics of eligible participants with upper gastrointestinal cancer treated with adjuvant nivolumab.

NCT ID: NCT06357819 Completed - Hepatitis C Clinical Trials

INSTI® HCV (Hepatitis C Virus) Antibody Self-Test Contrived Result Interpretation

Start date: October 12, 2023
Phase:
Study type: Observational

The purpose of this Interpretation Assessment was to document if "lay" people, non-professional and inexperienced in self-testing, were able to successfully perform the steps to use a Hepatitis C Virus (HCV) Self-Test (HCVST) device, without product familiarization [demonstration].

NCT ID: NCT06355817 Completed - Surgery Clinical Trials

Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration

Start date: September 21, 2023
Phase: N/A
Study type: Interventional

To compare the efficacy of topical tapping vs vibration in lowering pain scores for periocular anesthesia injections.