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NCT ID: NCT01368289 Active, not recruiting - Colonic Polyps Clinical Trials

Australian Multicentre Colonic Endoscopic Mucosal Resection Study

ACEEMR
Start date: September 2008
Phase:
Study type: Observational

A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis.

NCT ID: NCT01366274 Active, not recruiting - Clinical trials for Critically Injured Mechanically Ventilated Trauma Patients

Protective Manual Hyperinflation in Acute Mechanically Ventilated Trauma Patients

Start date: September 2007
Phase: N/A
Study type: Interventional

This single-blinded randomized study aims to compare two methods of manual hyperinflation (protective - moderate tidal volumes with positive end expiratory pressure) and non-protective (large tidal volume and no positive end expiratory pressure) in ventilated acute trauma patients, to investigate the effect on inflammatory markers, lung compliance, oxygenation and sputum volume.

NCT ID: NCT01365065 Active, not recruiting - HIV Positive Clinical Trials

Safety and Effect on HIV Transcription of Vorinostat in Patients Receiving Suppressive Combination Anti-retroviral Therapy

Start date: May 2011
Phase: Phase 2
Study type: Interventional

The objective of the study is to assess the safety and ability of vorinostat, a drug currently licensed for the treatment of a type of lymphoma, to 'turn on' dormant HIV infected CD4 T-cells.

NCT ID: NCT01364909 Active, not recruiting - Sepsis Syndromes Clinical Trials

Exercise in Critically Ill Patients With Sepsis

Start date: June 2007
Phase: N/A
Study type: Interventional

This study will investigate whether early exercise in critically ill patients will decrease inflammatory markers, increase pro-inflammatory markers and prevent loss of muscle mass.

NCT ID: NCT01358877 Active, not recruiting - Breast Cancer Clinical Trials

A Study of Pertuzumab in Addition to Chemotherapy and Trastuzumab as Adjuvant Therapy in Participants With Human Epidermal Growth Receptor 2 (HER2)-Positive Primary Breast Cancer

APHINITY
Start date: November 8, 2011
Phase: Phase 3
Study type: Interventional

This randomized, double-blind, placebo-controlled, two-arm study will assess the safety and efficacy of pertuzumab in addition to chemotherapy plus trastuzumab as adjuvant therapy in participants with operable HER2-positive primary breast cancer. This study will be carried out in collaboration with the Breast International Group (BIG).

NCT ID: NCT01347775 Active, not recruiting - Renal Failure Clinical Trials

Inspiratory Muscle Training in Patients With End Stage Renal Failure

Start date: December 2007
Phase: Phase 4
Study type: Interventional

This study will investigate whether inspiratory muscle training in patients with end stage renal failure can improve strength and function.

NCT ID: NCT01343277 Active, not recruiting - Clinical trials for Advanced Liposarcoma or Leiomyosarcoma

A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma

Start date: June 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate whether overall survival for the trabectedin group is superior to the dacarbazine group for patients with advanced L-sarcoma (liposarcoma or leiomyosarcoma).

NCT ID: NCT01337401 Active, not recruiting - Clinical trials for Alveolar Soft-part Sarcoma

A Trial of Cediranib in the Treatment of Patients With Alveolar Soft Part Sarcoma (CASPS)

CASPS
Start date: July 2011
Phase: Phase 2
Study type: Interventional

The study is a two-arm, randomised, double-blind, international, multi-centre phase II trial of cediranib in Alveolar Soft Part Sarcoma (ASPS). The study aims to confirm the ability of cediranib to halt disease progression in patients with metastatic ASPS, as measured by the change in tumour size at 24 weeks after randomisation, and to produce objective response according to RECIST criteria.

NCT ID: NCT01327976 Active, not recruiting - Obesity Clinical Trials

ReCharge Clinical Trial

ReCharge
Start date: May 2011
Phase: Phase 3
Study type: Interventional

To determine the safety and efficacy of the Maestro RC2 System in producing weight loss in obese subjects.

NCT ID: NCT01298323 Active, not recruiting - Clinical trials for Medullary Thyroid Cancer

Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib Treatment

88
Start date: February 25, 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effect of patient outreach program on the proportion of time patients with MTC experience moderate or severe AEs during first 12 months of treatment with vandetanib