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Cough clinical trials

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NCT ID: NCT06380023 Completed - Airway Aspiration Clinical Trials

An Investigation Into the Dispersion Pattern During Coughing and Open Nasopharyngeal Suction Using Various Barrier Devices

Start date: September 1, 2022
Phase:
Study type: Observational

The aim of the study is to examine the air dispersion pattern and the environmental influence of open airway suction in general ward setting. Secondly, the study is aimed at identifying a simple & practical enclosure device in general ward. Suction will be performed in manikin in supine lying. Nasopharyngeal suction will be performed by physiotherapist with working experience more than 1 years. Besides, surgical mask & enclosure tent will be adopted as the enclosure barrier device in this study. Research Question 1. To assess the extent of the environmental contamination during coughing and simulated airway suction 2. To measure the air particle count during coughing and simulated open airway suction. 3. To evaluate how effective the enclosure barrier in reducing the air particle dispersion during open airway suction.

NCT ID: NCT06341244 Completed - Postoperative Care Clinical Trials

Air Stacking Technique Efficacy on Peak of Expiratory Flow and Cough Peak Flow in Non-cardiac Thoracic Surgery

Start date: August 20, 2019
Phase: N/A
Study type: Interventional

After thoracic surgical intervention, patients often feel intense pain with respiratory movements reduction making coughing less effective. The air stacking improves peak of expiratory flow (PEF) and cough peak flow (CPF) in neuro myopathies, thus raising the hypothesis that may also be effective in patients undergoing thoracic surgeries. Objectives: To evaluate the effectiveness, safety and feasibility of air stacking on postoperative PEF and CPF in patients undergoing thoracic surgeries. Methods: Patients undergoing thoracic surgery underwent air stacking on 3th PO. Dyspnea, pain, SpO2, maximum inspirational pressure (MIP), maximum expiratory pressure (MEP), PEF and CPF were evaluated in pre and postoperatory.

NCT ID: NCT06275425 Completed - Cough Clinical Trials

Comparison of the Coughing Frequency of Remimazolam Total Intravenous Anesthesia Versus Inhalational Anesthesia

Start date: June 25, 2023
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial. Adult patients undergoing thyroidectomy under general anesthesia at Severance Hospital and Yonsei Cancer Center are included in tis study. For intervention group, patients receive anesthesia with total intravenous remimazolam, while for control group, patients receive anesthesia with inhalation anesthetic. The primary end point of the study is to determine whether coughing during endotracheal tube extubation is less when anesthesia is maintained with intravenous remimazolam compared to inhalation anesthetics. The secondary end points are cough score (graded into 4 levels), frequency of reoperation due to postoperative bleeding, These include the frequency of hypertension during the extubation process and whether additional painkillers are used in the recovery room.

NCT ID: NCT06213116 Completed - Cough Clinical Trials

Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Comparing the efficacy between Lignocaine given via MADgic Atomizer and Lignocaine Pump Spray pre endotracheal intubation in adult undergoing General Anesthesia.

NCT ID: NCT06199830 Completed - Asthma Clinical Trials

A Retrospective Study on the Differentiation Between Cough Variant Asthma and Chronic Cough

Start date: March 1, 2022
Phase:
Study type: Observational

this study aimed to compare characters in pulmonary function of patients with cough variant asthma and chronic cough and establish a diagnostic model.

NCT ID: NCT06106880 Completed - Headache Clinical Trials

Alleviation of Common Cold Symptoms

Start date: May 25, 2022
Phase: Phase 1
Study type: Interventional

Upper respiratory infections (URIs) have long posed a significant burden to the US healthcare system. Well before the coronavirus disease of 2019 (COVID-19) pandemic they have been among the most common acute outpatient illnesses, causing 75-100 million physician visits each year on average, and costing the health care system billions of dollars annually. This double-blind randomized placebo-controlled study tested the efficacy of two anti-inflammatory throat sprays against placebo and against a throat spray taken in conjunction with 325mg of aspirin, a well-known systemically administered cyclooxygenase (COX) inhibitor. Participants having common cold symptoms lasting less than two days were enrolled and given treatment to administer at home. Various common cold symptoms were assessed and measured via clinically validated self-assessment scales. Participants were screened for influenza and COVID-19 before enrollment and were excluded if found positive.

NCT ID: NCT06040034 Completed - Cough Clinical Trials

Bolus vs. Continuous IV Lidocaine Against Post-Extubation Cough in Post-Thyroidectomy Patients

Start date: February 2, 2023
Phase: Phase 2
Study type: Interventional

The goal of this randomized controlled trial is to compare the effect of lidocaine bolus intravenous administration to lidocaine continuous intravenous administration in post thyroidectomy patients to observe the effect against post-extubation cough. The main questions it aims to answer are: - Cough incidence on both groups - Which method is preferable to reduce post-extubation cough incidence

NCT ID: NCT05812209 Completed - Pain Clinical Trials

Stellate Ganglion Block to Treat Long COVID 19 Case Series

Start date: September 1, 2022
Phase:
Study type: Observational

An assessment of the effectiveness of Stellate Ganglion Block in alleviating symptoms of Long COVID-19.

NCT ID: NCT05681338 Completed - Inguinal Hernia Clinical Trials

Effect of the Coughing Technique During Subcutaneous Heparin Injection

Start date: March 17, 2022
Phase: N/A
Study type: Interventional

Objective: to examine the effect of the medium intensity coughing technique during subcutaneous low molecular weight heparin injection on pain severity and individual satisfaction in general surgery patients. Method: a prospective, quasi-experimental study included 100 patients who had prescribed a subcutaneous low molecular weight heparin injection once in 24 hours. Each patient received two injections by the same researcher using standard injection technique with medium intensity coughing technique and only standard injection technique.

NCT ID: NCT05642559 Completed - Chronic Cough Clinical Trials

Study for the Development and Validation of Chronic Cough Patient Perspective Questionnaire

MISP
Start date: December 1, 2022
Phase:
Study type: Observational

Starting from Chronic Cough Impact Querstionnaire (CCIQ), of which we are the authors and copyright holders, it will be developed and validated a shortened version with psychometric properties allowing the use in the evaluation of single patient (Chronic Cough Patient Perspective). The CCPP will allow to unmask the problem, reduce underdiagnosis, increase awareness on chronic cough, measure the impact of the chronic cough and its treatments on the patient's life.