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NCT00918242 Clinical Trial

Prevalence of Coronary Artery Disease in the Siblings of Premature Coronary Heart Disease

Coronary Heart Disease Clinical Trial

Official title:
Assessment of Occult CAD: Premature CAD Sibling Study (PreCASS)

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00918242
Other study ID # 20090616
Secondary ID
Status Recruiting
Phase N/A
First received June 10, 2009
Last updated July 20, 2012
Start date June 2009

Study information
Verified date July 2012
Source Yonsei University
Contact Hyuk-Jae Chang, MD, PhD
Phone 82-2-2228-8461
Email hjchang@yuhs.ac
Is FDA regulated No
Health authority Korea: Food and Drug Administration
Study type Observational

Clinical Trial Summary

The aim of this prospective study is to investigate the prevalence of coronary artery disease using computed tomography with family history of premature coronary heart disease

Recruitment information / eligibility
Status Recruiting
Enrollment 87
Est. completion date
Est. primary completion date September 2012
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- within 1 year

- the siblings of premature coronary heart disease (male<55years old, female<65yeasrs old: Framingham Heart Study) patients admitted relevant hospital

Exclusion Criteria:

- Documented coronary heart disease

- experienced adverse events with relevant treatment

- contraindicated with beta-blockers

- Any woman of childbearing potential who is pregnant, seeking to become pregnant or suspects

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Korea, Republic of Yonsei University Severance Hospital Seoul

Sponsors (2)
Lead Sponsor Collaborator
Yonsei University Korean Society of Lipidology and Atherosclerosis

Country where clinical trial is conducted

Korea, Republic of, 

References & Publications (1)

Arad Y, Spadaro LA, Goodman K, Newstein D, Guerci AD. Prediction of coronary events with electron beam computed tomography. J Am Coll Cardiol. 2000 Oct;36(4):1253-60. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary evaluation of prevalence to coronary artery disease using CT within 2 weeks from CT scanning No
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