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Heart and Estrogen-Progestin Replacement Study (HERS)

Coronary Heart Disease Clinical Trial

Official title:
Heart and Estrogen-Progestin Replacement Study (HERS)

Clinical Trial Summary

The purpose of the study is to determine whether hormone replacement therapy in post menopausal women with coronary artery disease prevents future heart attacks or death from coronary heart disease.

Clinical Trial Description

A randomized, blinded trial in post menopausal women with cornaornary artery disease to test the hypothesis, among 2340 women who have a uterus, that those randomized to receive estrogen-progestin replacement therapy (Premanrin .625 mg daily plus medroxygrprogesterone acetate 2.5 mg daily) have the same frequency on new CHD events (myocardial infarction and CHD death) as those randomized to placebo. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00319566
Study type Interventional
Source University of California, San Francisco
Contact
Status Completed
Phase Phase 3
Start date July 1992
Completion date July 2001
View Details
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