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Coronary Heart Disease clinical trials

View clinical trials related to Coronary Heart Disease.

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NCT ID: NCT02740621 Completed - Clinical trials for Coronary Heart Disease

The Impact of Opioids in Coronary Heart Disease

MIOP/TRAPS
Start date: January 2016
Phase:
Study type: Observational

In this study, the risk of opioid medications on coronary heart disease in adults is investigated. Patients with the necessity of a coronary angiography and control patients with a non-cardiac disease of the same hospital are inquired with a standardized questionnaire about demographic and clinical risk factors for heart attack. An impact of opioid medications on coronary heart disease is hypothesised (MIOP). In addition, all patients with coronary angiography should be consulted twice (after 3 and 6 months) to find out how many of these patients have developed a refractory angina pectoris (TRAPS).

NCT ID: NCT02688868 Completed - Clinical trials for Coronary Heart Disease

Evaluation of New Specifications (2.25mm) of FirehawkTM in the Treatment of Coronary Heart Disease ( Firehawk_2.25 )

Start date: May 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evalute the clinical safety and effectiveness of released specification (2.25mm) of FirehawkTM Sirolimus target-eluting coronary stent system.

NCT ID: NCT02688842 Completed - Clinical trials for Coronary Heart Disease

Evaluation of New Specifications (38mm) of FirehawkTM in the Treatment of Coronary Heart Disease

Firehawk_38
Start date: May 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evalute the clinical safety and effectiveness of released specification (38mm) of FirehawkTM Sirolimus target-eluting coronary stent system.

NCT ID: NCT02688829 Completed - Clinical trials for Coronary Heart Disease

The First-In-Man Pilot Study of Firehawk

Start date: December 2009
Phase: N/A
Study type: Interventional

This is a small-scale pilot clinical study of the Rapamycin-Eluting Coronary Stent System of Microport for the first time to assess the preliminary safety and feasibility used in the human body. And provide evidence for subsequent large-scale, multi-center, randomized controlled clinical trials, then provide the basis for the formal application of the product in China.

NCT ID: NCT02550717 Completed - Stroke Clinical Trials

Epidemiological Study on the Safety of Aspirin in The Health Improvement Network (THIN)

EPISAT
Start date: September 1, 2015
Phase:
Study type: Observational

To investigate the risk of major bleeding (including gastrointestinal and intracranial bleeding episodes) among new users of low-dose acetylsalicylic acid (ASA) in clinical practice

NCT ID: NCT02546557 Completed - Clinical trials for Coronary Heart Disease

Optilene® Suture for Coronary Artery Bypass Graft Surgery

OPTICABG
Start date: November 10, 2015
Phase:
Study type: Observational

The study is a voluntary study, initiated by B. Braun to collect clinical data for Optilene® suture concerning its key indication.

NCT ID: NCT02519491 Completed - Clinical trials for Coronary Heart Disease

Utility of a Smart Phone Application in Assessing Radial Artery Patency - the CAPITAL iRADIAL Study

Start date: July 2015
Phase: N/A
Study type: Interventional

Accessing the arteries of the heart through the blood vessels of the wrist is becoming increasingly popular. By obtaining access via the artery in the arm as opposed to the groin, there is less risk of complications and improved patient satisfaction. However, using the wrist can cause blockage of the artery after the procedure. If there is too little blood flow from a second artery that supplies the hand, this could result in significant injury. Therefore, it is important to test these blood vessels in the wrist prior to having this procedure. The best way to evaluate these arteries involves the use of ultrasounds but this takes a long time and is expensive. Therefore, the artery is usually evaluated with a clinical test known as the modified Allen's test, which relies on the doctor watching the flushing of the hand during compression of the artery. Currently smart phones with cameras are able to assess blood flow by passing light through the skin and watching differences in brightness. This may be a better way to assess the arteries in the hand as it is less subjective than simply watching the flushing of the hand. This study aims to assess the ability of an iPhone application in determining whether there is sufficient blood flow through the arteries of the wrist and comparing it to the clinical test commonly used.

NCT ID: NCT02493413 Completed - Obesity Clinical Trials

The Stress-release Effects of Exercise in Obese Are Determined by DS14 Score and T-cell Activation Status

Start date: January 2012
Phase: N/A
Study type: Observational

The purpose of the study was to analyze negative affectivity (NA) and social inhibition (SI) inquired by DS14 score in type D personality (distressed personality) to the relation of autonomic regulation of heart function (HRV) and immune response (T lymphocyte) among obese patients within coronary heart disease group (CHD). As stress is the key psychological activator of the hypothalamic-pituitary-adrenal axis (HPA axis) and therefore an important risk factor for diminished immune competency and prevalence of chronic conditions such as obesity, investigators chose exercise as the stress release intervention, especially as chronic stress may have a role in obesity, related to initiation or exacerbation of the condition. Abnormal regulation of the hypothalamic-pituitary-adrenal axis is additionally associated with chronic inflammatory conditions. Proinflammatory T-lymphocytes are present in visceral adipose tissue and may contribute to local inflammatory cell activation before the appearance of macrophages, suggesting that these cells could play an important role in the initiation and perpetuation of adipose tissue inflammation.

NCT ID: NCT02440893 Completed - Clinical trials for Coronary Artery Disease

Understanding the Effect of Metformin on Corus CAD (or ASGES)

MET
Start date: September 2013
Phase:
Study type: Observational

The study goal was to understand the effect of Metformin on Age/Sex/Gene Expression Score (ASGES) or Corus CAD (henceforth "Corus") in pre-diabetic patients who are medication naive. This study provided data to determine if the Corus CAD (ASGES) signature was different in pre-diabetic patients when metformin was newly prescribed and taken.

NCT ID: NCT02417376 Completed - Periodontitis Clinical Trials

Changes in the Risk Factors of Coronary Heart Disease Observed After Scaling and Root Planing

Start date: May 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether scaling and root planing as a periodontal intervention helps in improving the overall health of patients suffering from coronary heart disease.