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Coronary Disease clinical trials

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NCT ID: NCT04943354 Completed - Clinical trials for Cardiovascular Diseases

Associations of Combinations of Single-nucleotide Polymorphisms in Women With Premature Ovarian Failure

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Research objective. - To study the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with non-communicable diseases and adverse outcomes in women with premature ovarian failure. Research objectives: - To study the associations between combinations of single-nucleotide polymorphisms and behavioural risk factors with heart rate disorders and adverse outcomes in women with premature ovarian failure - Examine the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with stable STIs in women with premature ovarian failure. - Examine the associations between combinations of single nucleotide polymorphisms and behavioural risk factors with thrombomolia in women with premature ovarian failure - Study the associations between combinations of single nucleotide polymorphisms and behavioural risk factors and adverse cardiovascular outcomes in women with premature ovarian failure.

NCT ID: NCT04941560 Completed - Clinical trials for Coronary Artery Disease

Assessing the Association Between Multi-dimension Facial Characteristics and Coronary Artery Diseases

Start date: September 6, 2021
Phase:
Study type: Observational

The purposes of this study are 1) to explore the association between multi-dimension facial characteristics and the increased risk of coronary artery diseases (CAD); 2) to evaluate the diagnostic efficacy of multi-dimension appearance factors for coronary artery diseases.

NCT ID: NCT04930939 Completed - Clinical trials for Coronary Artery Disease

Heart Rate Variability-guided Training in Cardiac Rehabilitation

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Background: Previous studies have reported that heart rate variability (HRV)-guided training is a better option for improving autonomic function and aerobic capacity (i.e., oxygen uptake and power output at second ventilatory threshold and maximal exercise) during a cardiopulmonary exercise test compared to predefined training in sedentary and physically active healthy people. Nevertheless, none of these previous studies have been carried out with coronary artery disease (CAD) patients. Methods: A total of 23 patients with CAD were divided into HRV-guided training group (HRV-G; n = 11) and predefined training group (PRE-G; n = 12). All patients trained three days a week for eight weeks (18 sessions). Patients allocated in the PRED-G carried out a previously established cardiac rehabilitation programme, combining sessions of moderate and high intensity, while patients allocated in the HRV-G carried out sessions of moderate or high intensity on the basis of their daily HRV assessments. The weekly averaged and isolated parasympathetic-related HRV indices, heart rate recovery, resting heart rate, and aerobic capacity were assessed before and after of the training programme.

NCT ID: NCT04901767 Completed - Clinical trials for Coronary Artery Disease

Coronary Artery Endothelial Dysfunction With Drug Coated Balloons

SPARTAN-VM
Start date: March 23, 2021
Phase:
Study type: Observational

Use of intracoronary acetylcholine to investigate endothelial function in coronary arteries treated with either drug coated balloon angioplasty of drug eluting stents.

NCT ID: NCT04898296 Completed - Coronary Disease Clinical Trials

Exploration of Possible Reasons for the Discrepancy Between Expectation and Indication of Subjective Perceived Exertions

Ex-6-rate
Start date: July 1, 2021
Phase:
Study type: Observational

The 6-minute walk test is a test of physical performance in physiotherapy with lungs and heart patients (Pollentier 2010). However, only 8 and 11% of patients in everyday test situations report a score of 7 or higher on a scale of 0-10 for effort (Jehn 2009). This study is intended to explore, based on grounded theory, why the majority of patients do not assess themselves according to the almost maximum performance.

NCT ID: NCT04897126 Completed - Clinical trials for Coronary Heart Disease

Efficacy and Safety of Shexiang Baoxin Pill in Patients With Ischemia With Non-Obstructive Coronary Artery

LESS
Start date: May 11, 2021
Phase: Phase 4
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled clinical trial. Patients were treated with the trial drug or placebo in a 1:1 ratio. The control group was treated with placebo 4 pills / day, 3 times / day on the basis of conventional treatment until the end of follow-up, while the experimental group was treated with MUSK Pill 4 pills / day, 3 times / day on the basis of conventional treatment until the end of follow-up.

NCT ID: NCT04888260 Completed - Clinical trials for Coronary Artery Disease

Plasma Mannose Associated Parameter Levels in Nondiabetic Coronary Artery Disease

Start date: January 10, 2018
Phase:
Study type: Observational

Aims: Nondiabetic patients have been studied to determine whether modest elevations in plasma mannose levels may be associated with a greater incidence of coronary artery disease (CAD). Methods: The plasma mannose, lipids (triglyceride, LDL, HDL, LDL, VLDL) and LDH levels were successfully will be evaluated with respect to subsequent coronary artery disease using records 120 nondiabetic patients and 120 healthy volunteers. CAD was identified from myocardial infarction and new diagnoses of angina. The associations between mannose levels and serum lipid parameters will be investigated.

NCT ID: NCT04864119 Completed - Clinical trials for Type 2 Myocardial Infarction

DEFINing the PrEvalence and Characteristics of Coronary Artery Disease Among Patients With TYPE 2 Myocardial Infarction Using CT-FFR

DEFINE TYPE2MI
Start date: April 11, 2021
Phase:
Study type: Observational

The primary objectives of this study include: - determine the prevalence of coronary artery disease among patients with type 2 myocardial infarction - determine the prevalence of hemodynamically significant stenosis among patients with type 2 myocardial infarction The investigators hypothesize that patients with type 2 myocardial infarction will have a high burden of coronary artery plaque and a high prevalence of obstructive coronary artery disease with hemodynamic significance.

NCT ID: NCT04863053 Completed - Coronary Disease Clinical Trials

Thromboxane B2 and Platelet Function Testing as Measures of Aspirin Resistance in Hong Kong Chinese Patients

Start date: April 2, 2015
Phase:
Study type: Observational

The hypotheses of the study are that the diagnostic accuracy of Multiplate® device for diagnosis of aspirin resistance is comparable to the serum TXB2 assay and that certain genetic polymorphisms and phenotypic factors significantly influence the antiplatelet effect of aspirin and contribute to aspirin resistance observed in this study.

NCT ID: NCT04862351 Completed - Clinical trials for Coronary Heart Disease

Effectiveness of TechCR Among CHD Patients

TechCR
Start date: February 26, 2021
Phase: N/A
Study type: Interventional

During this ongoing pandemic, there is a crucial need for innovative approaches to deliver CR programmes other than frequent face-to-face sessions at the centre-based CR to reduce the number of times people come close in contact with others or gathering in large groups. This is a single setting, 2-arm parallel randomised clinical trial which aims to examine the effects of technology-assisted interventions in hybrid cardiac rehabilitation (TecHCR) among the coronary heart disease patients. Eligible participants will be randomly assigned into either intervention group (IG) or control group (CG) in 1:1 ratio using the computerised permuted blocks, alternating block sizes of 4 or 6. All participants will be followed up for three months and six months with data collection at baseline, (T0), three-month (T1) and six-month (T2) time points.