Quantitative Analysis of Functional CT Imaging of Coronary Atherosclerosis

Status Completed

Clinical Trial Summary

The purpose of this prospective observational study is to evaluate the diagnostic and prognostic performance of a "one-stop" comprehensive coronary artery anatomy and function assessment for CAD.

Clinical Trial Description

Coronary CT angiography (CCTA) has become a reliable diagnostic technique to evaluate coronary artery disease (CAD) with high sensitivity and a negative predictive value. However, CCTA provides only anatomic information and tends to overestimate stenosis severity and is limited in its ability to diagnose myocardial ischemia. Undertaking additional CT myocardial perfusion imaging(CT-MPI) and CT-FFR improves specificity and positive predictive value, reducing unnecessary invasive coronary angiography. The purpose of this prospective observational study is to evaluate the diagnostic and prognostic performance of a "one-stop" comprehensive coronary artery anatomy and function assessment for CAD. SPECT myocardial perfusion imaging (SPECT-MPI)and invasively measured fractional flow reserve (FFR) will serve as the reference standard. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04986410
Study type	Observational
Source	Qilu Hospital of Shandong University
Contact
Status	Completed
Phase
Start date	July 1, 2017
Completion date	December 31, 2020

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