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Influence of Intensive Lipid-lowering on FFRCT (The FLOW-PROMOTE Study) — FlowPromote  

Coronary Artery Disease Clinical Trial

Official title:
Influence of Intensive Lipid-lowering With Statin and Ezetimib Prescription on Computed Tomography Derived Fractional Flow Reserve in Patients With Stable Chest Pain (The FLOW-PROMOTE Study)

Clinical Trial Summary

The FLOW-PROMOTE Study is an investigator-initiated, Danish multicenter study of patients with stable chest pain investigating whether lipid lowering is associated with recovery of impaired coronary flow as assessed by CT derived fractional flow reserve (FFRCT).

Clinical Trial Description

Multicenter study (4 centers in Denmark), including 120 patients with stable chest pain and hemodynamically significant coronary artery disease as assessed by FFRCT. By using two lipid lowering treatment strategies ("usual" vs "intensive" care) over 18 months, the effect on coronary plaque regression and flow recovery are assessed from repeated CT angiograms with plaque and FFRCT analyses at 9 and 18 months. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04737408
Study type Interventional
Source Aarhus University Hospital Skejby
Contact Bjarne L Noergaard, MD, PhD
Phone +4540136570
Email bnorgaard@dadlnet.dk
Status Recruiting
Phase Phase 3
Start date May 13, 2020
Completion date August 2023
View Details
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