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Early Detection of Coronary Artery Disease by Polygenic and Metabolic Risk Scoring — EDCAD-PMS  

Coronary Artery Disease Clinical Trial

Official title:
Early Detection of Coronary Artery Disease by Polygenic and Metabolic Risk Scoring in at Risk Patients: Comparison With Coronary Computed Tomography

Clinical Trial Summary

The overall goal of this study is to develop a combined polygenic risk score (PRS) and metabolic risk score (MRS) and determine its impact on selecting community members for CCS. The trial component of this study will compare the use of these scores to motivate people to adhere to therapy, an ongoing challenge for clinicians, by providing feedback in a meaningful form to both the clinicians and the patients.

Clinical Trial Description

Patients undergoing a polygenic risk score (PRS), metabolic risk score (MRS) and coronary calcium score (CCS) will be randomized to receive PRS and CCS information and followed for the reduction of risk over 12 months. This information will provide information about how to motivate people to adhere to therapy, by providing feedback in a meaningful form to both the clinicians and the patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04604353
Study type Interventional
Source Baker Heart and Diabetes Institute
Contact Carla Duarte, BS
Phone +61385321550
Email carla.duarte@baker.edu.au
Status Recruiting
Phase N/A
Start date December 7, 2020
Completion date October 30, 2023
View Details
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