Watch Laser Acupuncture With Nasal Radiation for Prevention of Coronary Artery Disease

Coronary Artery Disease Clinical Trial

Official title:

Laser Hemotherapy Trial for Coronary Artery Disease Prevention in High Risk Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03454594
• Other study ID #: P.T.REC/012/001561
• Status: Completed
• Phase: N/A
• Start date: May 1, 2018
• Est. completion date: December 30, 2018

Study information

• Verified date: February 2019
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will evaluate the effect of low level laser blood radiation applied to all participants for prevention of coronary artery disease in patients with high risk (hypertension,high blood viscosity, hypercholesterolemia as well as related immune issues)

Description:

The areas of low - intensity laser use have expanded in several conditions by different mechanisms and ways. Hypertension as one of coronary artery disease risk factors and early indicator of future cardiovascular events with high blood viscosity and elevated blood cholesterol levels with immune-pathological basis became necessary issue to be handled. Low Level Laser irradiation effects on blood is very essential way in revealing the mechanisms of the action of laser radiation on biological tissues by means of changes in metabolism, leading to molecular, cellular and systemic changes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: December 30, 2018
• Est. primary completion date: August 5, 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 55 Years to 65 Years

Eligibility

Inclusion Criteria:

• stage I hypertensive patients

• patients from 30 to 34.9 kg/m2 body mass index

• medically stable patients

• all participants have sufficient cognition enough to understand the requirements of the study

Exclusion Criteria:

• history of malignant disease

• smoking

• history of progressive fatal disease

• history of drug or alcohol abuse

• blood donation within at least 30 days

• pregnant, trying to be pregnant or breast feeding

• cognitive impairment that will make it difficult to partake in the study

Related Conditions & MeSH terms

• Cardiovascular Risk Factor
• Coronary Artery Disease
• Coronary Disease
• Myocardial Ischemia

Intervention

Device:
• low level laser hemotherapy
semiconductor laser therapeutic instrument irradiate the circulating blood in the vessels of left hand acupoint and the mucosal tissue in the nasal cavity

Locations

Country	Name	City	State
Egypt	Cairo	Giza	Dokki

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	changes of blood pressure	measuring blood pressure before and after each low level laser radiation	8 weeks
Secondary	changes in blood viscosity	measuring changes in blood viscosity before and after low level laser radiation session	8 weeks
Secondary	change in IL-17 level	measuring changes in IL-17 level before and after low level laser radiation session	45 days
Secondary	change in functional capacity	measuring of 6 minute walking test before and after low level laser irradiation as an indicator of functional capacity improving	70 days
Secondary	change in CD 8 (cluster of differentiation 8) level	measuring changes in CD 8 (cluster of differentiation 8) level before and after low level laser radiation session	45 days
Secondary	change in TC (total cholesterol) level	measuring changes in TC (total cholesterol) level before and after low level laser radiation session	60 days
Secondary	change in LDL (low density lipoprotien) level	measuring changes in LDL (low density lipoprotien) level before and after low level laser radiation session	60 days
Secondary	change in TG (triglyceride) level	measuring changes in TG (triglyceride) level before and after low level laser radiation session	60 days
Secondary	change in HDL (high density lipoprotien) level	measuring changes in HDL (high density lipoprotien) level before and after low level laser radiation session	60 days