Knowledge-based Iterative Model Reconstruction at Low-kilovoltage (kV) Cardiac Computed Tomography (CT)

Coronary Artery Disease Clinical Trial

Official title:

Value of Knowledge-based Iterative Model Reconstruction at Low-kilovoltage Cardiac 256-slice CT: A Comparison of Filtered Back Projection-, Hybrid-, and Iterative Model Reconstruction

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01896674
• Other study ID #: Kuma1478
• Status: Completed
• Phase: N/A
• First received: July 8, 2013
• Last updated: July 10, 2013
• Start date: May 2012

Study information

• Verified date: July 2013
• Source: Kumamoto University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Japan: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of this study was to compare FBP-, hybrid IR-, and IMR techniques to assess their role in the identification of coronary artery disease and abnormalities in cardiac structures.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 21
• Est. primary completion date: January 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 45 Years to 85 Years

Eligibility

Inclusion Criteria:

• A BMI of 27 kg/m2 or less and a coronary calcium score of less than 1,000 Agatston units.

Exclusion Criteria:

• BMI exceeded 27 kg/m2

• renal dysfunction (serum creatinine level > 1.5 mg/dl)

• atrial fibrillation

• prior coronary artery bypass grafting

• heart failure (New York Heart Association class III-IV)

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Coronary Artery Disease
• Coronary Disease
• Myocardial Ischemia

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Kumamoto University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Contrast to noise ratio of coronary arteries		6 months	No