Single Blind Randomized Study to Determine the Sensitivity and Specificity of 2 Non-invasive Markers of Early Coronary Disease

Coronary Artery Disease Clinical Trial

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT01742156
• Other study ID #: OPTH-CAD
• Status: Terminated
• Phase: N/A
• First received: December 3, 2012
• Last updated: April 5, 2017
• Start date: January 2013
• Est. completion date: September 2013

Study information

• Verified date: April 2017
• Source: McGill University Health Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Diagonal ear lobe crease and microcirculatory disorder in the conjunctiva are both non invasive methods documented in the literature as early signs of coronary artery disease. We wish to study the sensitivity and specificity of both signs by conducting a single blind study involving patients with documented presence or absence of coronary artery disease via angiogram.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 10
• Est. completion date: September 2013
• Est. primary completion date: June 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 70 Years

Eligibility

Inclusion Criteria:

• age 20 to 70 years old

• angiogram within past 12 weeks

• stable during post angio period

• willing to provide informed consent

Exclusion Criteria:

• previous eye surgery including cataract surgery

• previous ophthalmologic disorders

• previous surgeries involving ears or ear lobes

Related Conditions & MeSH terms

• Coronary Artery Disease
• Coronary Disease
• Myocardial Ischemia

Locations

Country	Name	City	State
Canada	Royal Victoria Hospital	Montreal	Quebec

Sponsors (1)

Lead Sponsor	Collaborator
McGill University Health Center

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Presence of tortuosity of conjunctival vessels		1 year