Coronary Artery Disease Clinical Trial
Official title:
Exercise-training Before Coronary Artery Bypass Graft (CABG)
Verified date | February 2018 |
Source | Norwegian University of Science and Technology |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The aim is to evaluate the effect of exercise training upon endothelial function in the mammary artery of patients who are scheduled for CABG, as well as study the functional properties of single cells isolated from a small biopsy of the left ventricle obtained during surgery.
Status | Completed |
Enrollment | 40 |
Est. completion date | December 2016 |
Est. primary completion date | December 2016 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Scheduled for CABG both with and without heart failure Exclusion Criteria: - Unstable angina - Unable to walk on a treadmill (except those with heart failure who only will serve as a reference group) - Participation in another study |
Country | Name | City | State |
---|---|---|---|
Norway | Norwegian University of Science and Technology | Trondheim |
Lead Sponsor | Collaborator |
---|---|
Norwegian University of Science and Technology |
Norway,
Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A. Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Th — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Cardiovascular function and quality of life | Before and up to 1 year after intervention | ||
Secondary | Structure and function of cardiomyocytes | After the intervention period | ||
Secondary | Cardiomyocyte structure and function | after the intervention period |
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