Trial to Assess Chelation Therapy (TACT)

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the safety and effectiveness of ethylene diamine tetra-acetic (EDTA) chelation therapy in individuals with coronary artery disease.

Clinical Trial Description

EDTA chelation therapy involves repeated administrations of a synthetic amino acid to reduce atherosclerotic plaque and other mineral deposits throughout the cardiovascular system.

Participants will be randomly assigned to receive 40 infusions of either the standard chelation solution or placebo. The primary endpoint of this trial will be a composite of all cause mortality, myocardial infarction, stroke, coronary revascularization, and hospitalization for angina.

The results of TACT will provide either a significant positive result or an informative null result upon which rational clinical decision-making and health policy can be based. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00044213
Study type	Interventional
Source	Mt. Sinai Medical Center, Miami
Contact
Status	Completed
Phase	Phase 3
Start date	September 2003
Completion date	August 2012

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