Education Clinical Trial
Official title:
5-year Trend in Cohabitation Status, Academic Achievement and Socio-economic Indicators After Mild Traumatic Brain Injury: a National Register Study
Mild traumatic brain injury (mTBI) accounts for 70-90% of all diagnosed traumatic brain
injuries (TBI) affecting approximately 50-300 per 100.000 individuals annually. Persistent
post-concussion symptoms are reported in 15-80% of hospital admitted and outpatient treated
populations, affecting labour market attachment, academic achievement, income, socio-economic
status, social interactions, home management, leisure activities and cohabitation status.
The association between mTBI and long-term trends in cohabitation status, income, academic
achievement and socio-economic status has not been thoroughly explored. Previous studies
focus on children's academic performance after severe TBI and only few studies include early
adulthood and patients with mTBI. Trends in divorce rates are frequently conducted on severe
injuries or populations consisting of veterans. Additionally, all studies have failed to
apply a national register based design.
Aim The aim of the study is to examine the long-term associations between mTBI and trends in
cohabitation status, academic achievement and socio-economic status between pre-injury rates
and observed rates at 5 years post-injury. The hypothesis was that by 5 years mTBI would be
associated with increased odds of marital breakdown, decreasing academic achievement,
decreasing income, decreasing socio-economic status compared to the general population in
Denmark.
Methods:
The study is a national register based cohort study with 5 years follow-up of patients with
mild traumatic brain injury from 2008 - 2012 in Denmark.
Population:
Patients between 18-60 years diagnosed with concussion (ICD-10 S06.0) were extracted from the
Danish National Patient Register between (2003-2007). Patients with major neurological
injuries and previous concussions at the index date and 5 years before the index date
(1998-2007) were excluded. Patients who were not resident in Denmark 5 years before and
during the inclusion period were also excluded (1998-2007).
Data will be retrieved from several national databases, including: the Danish national
patient register, Danish Civil Registration System (CRS), the Danish Education Registers, the
Income Statistics Register and the Employment Classification Module (AKM).
One control of the general population were matched for each case on sex, age and
municipality.
Outcome measures are: Cohabitation status, Education, income and socio-economic status.
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