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Concussion, Mild clinical trials

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NCT ID: NCT06340100 Recruiting - Clinical trials for Cognitive Impairment

Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes

Start date: March 23, 2024
Phase:
Study type: Observational

This study investigates the potential relationship between prior concussions and their impact on both vestibular function and cognitive abilities in athletes participating in sports.

NCT ID: NCT06328023 Recruiting - Sleep Clinical Trials

Impact of Concussion History on Sleep and Physical Performance in Contact Sports Athletes

Start date: March 18, 2024
Phase:
Study type: Observational

This study investigates the correlation between a history of concussions and its effects on both sleep patterns and physical performance among athletes engaged in contact sports. By examining the relationship between concussion history, sleep quality, and athletic performance, this research aims to provide insights into the potential long-term implications of concussions on the well-being and performance of athletes in contact sports

NCT ID: NCT06212726 Not yet recruiting - Concussion, Mild Clinical Trials

RTL Concussion Communication

Start date: August 28, 2024
Phase: N/A
Study type: Interventional

This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL). The study will conduct a quasi-experimental school-based 2 phase study involving 200 students with SRRC. The first phase will be descriptive to evaluate current standards (n=50). Phase 2 will compare students whod receive either standard of care RTL (n=75) or RTL augmented by a communication tool (RTC+; n=75).

NCT ID: NCT06147596 Not yet recruiting - Concussion, Mild Clinical Trials

Heading in Football: Impact on Neural Blood Biomarkers

HEADLINE
Start date: June 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to evaluate the safety of heading in football. We will study the release of biomarkers in blood that reflect microscopic neural damage. The main questions this study aims to answer are: - Does participation in a football match lead to a change in biomarkers that reflect microscopic neural damage? - Is the dose of exposure during a football match related to the magnitude of change in biomarkers that reflect microscopic neural damage? Participants will participate in a regular football match and provide blood samples before and right after the football match. The football match will be recorded on video to count the number of headers of all participants.

NCT ID: NCT06093295 Recruiting - Concussion, Mild Clinical Trials

Non-invasive Brain Stimulation and Injury Risk Biomechanics

Start date: November 3, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the effects of repetitive transcranial magnetic stimulation (theta burst stimulation) on movement biomechanics (jump landing) among individuals with and without a concussion history. The main question it aims to answer is if theta burst stimulation to the left dorsolateral prefrontal cortex improves single- and dual-task jump landing reaction time and jump landing biomechanics compared to a control site (vertex) for individuals with and without a concussion history. Participants will be asked to perform a jump landing before and after the experimental (left dorsolateral prefrontal cortex) and control (vertex) theta burst stimulation protocol. The researchers will compare individuals with and without a concussion history to see if the effects differ between groups.

NCT ID: NCT05943561 Not yet recruiting - Concussion, Mild Clinical Trials

Biomarkers in Concussion

Start date: September 2023
Phase:
Study type: Observational

This will be an observational study measuring serum Neurofilament Light Chain concentrations and associated symptoms, with a control branch, and a post-concussion branch.

NCT ID: NCT05857761 Recruiting - Concussion, Mild Clinical Trials

GAIN Symptoms: Post-traumatic Headache

Start date: August 28, 2023
Phase: N/A
Study type: Interventional

The overall aim of the study is to advance the knowledge on the characterization and underlying pathophysiological mechanisms of persistent post-traumatic headache (PTH) with a direct impact on the ability to diagnose and manage PTH effectively. The investigators also aim to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS), a novel intervention on PTH.

NCT ID: NCT05849064 Recruiting - Concussion, Mild Clinical Trials

Concussion Treatment in Older Adults

Start date: September 7, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct the first randomized control trial for targeted treatments for concussion in adults 50 years or older. Participants will be enrolled at their first concussion clinical visit (V1) and their second study visit will occur after (up to 7 days) or concurrently with the participant's second concussion clinical visit, typically (but not limited to) between 21-31 days from V1.

NCT ID: NCT05847608 Not yet recruiting - Concussion, Mild Clinical Trials

Omega-3 Treatment for Concussion in Adolescents

CONCUSS
Start date: June 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test omega-3 fatty acid supplementation as a treatment in adolescents with a concussion. The main questions it aims to answer are: - Does supplementing with omega-3 fatty acids improve time to recovery following sport related concussion. - Does supplementing with omega-3 fatty acids improve health related quality of life following concussion. - Does supplementing with omega-3 fatty acids change post-concussion symptoms following concussion. - Does supplementing with omega-3 fatty acids change saliva concentrations of interleukin-6 following concussion. - Does supplementing with omega-3 fatty acids change saliva concentrations of cortisol following concussion. Participants will be randomized to receive either an omega-3 supplement or placebo after they have been diagnosed with a concussion. Researchers will compare the omega-3 supplement group and placebo group to see if omega-3 fatty acids, consumed as a treatment, can improve time to recovery, health related quality of life and symptom burden, and whether omega-3 fatty acids alter interleukin-6 and cortisol concentrations in saliva following a concussion.

NCT ID: NCT05771051 Completed - Concussion, Mild Clinical Trials

Australian University of California San Francisco (UCSF) Concussion in Athletes (AUSSIE-2)

AUSSIE-2
Start date: March 1, 2022
Phase:
Study type: Observational

Analysis of cardiac induced brain forces using cranial accelerometry has been shown to diagnose concussion in high school athletes. This trial expands on this observation by recording headpulse signals in a recently concussed athletes playing Australian rules football.