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Colonoscopy clinical trials

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NCT ID: NCT06192394 Not yet recruiting - Colonoscopy Clinical Trials

Gum Chewing and Walking Exercise: Impact on Bowel Preparation Quality and Patient Satisfaction

Start date: July 2024
Phase: N/A
Study type: Interventional

Colorectal cancers are a major global health problem, highlighting the critical importance of screening programs for early diagnosis and effective treatment. The success of colonoscopy largely depends on the quality of bowel preparation. Inadequate bowel preparation may reduce the effectiveness of colonoscopy and cause lesions to be missed. Previous research has shown the positive effects of diet, training, and polyethylene glycol use on bowel readiness. However, there is limited research on the effects of methods such as gum chewing and walking exercise. This study aims to evaluate the effects of gum chewing and walking exercise, as well as diet and medication, on the quality of bowel preparation and patient satisfaction during the bowel preparation process before colonoscopy. The study uses a randomized controlled, single-blind experimental design with three different groups: a control group, a gum chewing group, and a walking exercise group. Each group will be evaluated based on bowel preparation quality and patient satisfaction. The quality of bowel preparation will be determined using the Boston Bowel Preparation Scale, and factors such as polyp detection, workability of colonoscopy, and cecal intubation time will also be evaluated. Patient satisfaction levels will be evaluated by taking into account how satisfied the patients are with the colonoscopy procedure and their complaints before and after the procedure. The results of this study will contribute to a better understanding of the impact of chewing gum and walking exercise before colonoscopy on the quality of bowel preparation and patient satisfaction. Identifying effective methods to improve the quality of bowel preparation can contribute to a healthier society by raising the standard of nursing care. At the same time, this research may improve the comfort and effectiveness of the colonoscopy process for patients and benefit public health by increasing the effectiveness of colorectal cancer screening programs.

NCT ID: NCT06173297 Completed - Colorectal Cancer Clinical Trials

Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.

Start date: February 1, 2020
Phase:
Study type: Observational

The goal of this observational study was to assess the degree of agreement between the endoscopic and anatomopathological diagnosis of sessile serrated colorectal lesions in adult patients undergoing colonoscopy in Hospital Sírio-Libanes. The main questions it aimed to answer were: - The degree of agreement between endoscopic and anatomopathological diagnosis of sessile serrated colorectal lesions by calculating the Kappa Value of agreement. - To establish the detection rate of sessile serrated lesions and adenomas in the Endoscopy Department at Hospital Sírio-Libanês. - To evaluate the degree of agreement between endoscopic and anatomopathological diagnosis of sessile serrated colorectal lesions based on the resection method. - To assess the accuracy, positive predictive value, and negative predictive value of endoscopic diagnosis of serrated lesions compared to anatomopathological diagnosis. The data were prospectively collected through a form specifically designed for this project, that was completed immediately after the examination by the performing colonoscopist. All patients enrolled in this study agreed to participate in it and signed an informed consent form prior to the colonoscopy.

NCT ID: NCT06173258 Recruiting - Colonoscopy Clinical Trials

Water Exchange Colonoscopy With Artificial Intelligence-assisted Detection

Start date: December 18, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the detected adenoma per colonoscopy (APC) in participants undergoing screening, surveillance, and positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT). There will be two arms in this study: WE water control and water plus artificial intelligence (AI). The main question it aims to answer is whether the addition of AI into water exchange (WE) colonoscopy increases APC than WE alone. The control method will use water instead of air inserted into the colon. The study method will use a commercially available AI system plus water during the procedure. Researchers will compare APCs to see if the addition of AI increases detection of adenomas during WE colonoscopy.

NCT ID: NCT06159855 Active, not recruiting - Colonoscopy Clinical Trials

The Effect of Bowel Preparation Training Given to Patients Undergoing Colonoscopy

training
Start date: January 15, 2023
Phase: N/A
Study type: Interventional

This study was planned to examine the effect of bowel preparation training and monitoring given to patients planned to undergo colonoscopy on the level of anxiety, compliance with bowel preparation and bowel cleansing. The research sample was collected at the Sultan II. University of Health Sciences affiliated to the Istanbul Provincial Health Directorate between December 2022 and August 2023. 34 intervention and 34 control groups will be randomly selected from outpatients who apply to the Colonoscopy Unit of Abdülhamid Han Training and Research Hospital and meet the inclusion criteria. In this study, it is aimed to increase the effect of bowel preparation training, supported by nurses in the clinic and via instant messaging/calling or communication application, on patients' anxiety level, level of compliance with bowel preparation, and bowel cleansing in patients scheduled for colonoscopy.

NCT ID: NCT06151275 Completed - Colonoscopy Clinical Trials

Factors Predict Difficult Colonoscopy Before the Procedure: Prospective Registry Study

Start date: June 7, 2023
Phase:
Study type: Observational

In this study, the investigators aim to evaluate the relationship between cecal intubation time during colonoscopies and factors such as the patient's age, body mass index, history of constipation, Wexner constipation score, antidepressant use, and previous abdominal surgery. The objective is to assess factors that may predict longer cecal intubation times, especially in difficult colonoscopies. Prior to the procedure, informed consent will be obtained from patients scheduled for colonoscopy in the surgical endoscopy unit, and relevant information will be recorded. During the procedure, data will be collected, including cecal intubation time, if ileal intubation is performed, and the total procedure time.

NCT ID: NCT06117553 Completed - Colonoscopy Clinical Trials

Thorough Flushing Strategy During Colonoscopy Examination

Start date: August 1, 2023
Phase:
Study type: Observational

The investigators plan to adopt a thorough flushing strategy when withdrawing the endoscope, and have zero tolerance for the liquid and foam in the intestinal lumen. Observe and compare the impact of this strategy with traditional limited degree suction methods on the results of colonoscopy. The research group and the control group respectively adopted a thorough flushing strategy and a limited flushing strategy, and compared the total time of colonoscopy examination, the time of withdrawal, the detection rate of polyps, the detection rate of small polyps, and the amount of flushing fluid between the two groups. Analyze the value of thorough flushing strategy for the efficiency and quality of colonoscopy examination.

NCT ID: NCT06111937 Recruiting - Colonoscopy Clinical Trials

Time Interval After Gastric Emptying and Quality of Bowel Cleansing

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The goal of this [clinical trial] is to [explore the balance time point between the waiting time for intestinal preparation after gastric emptying and quality of bowel preparation.] in [patients with painless colonoscopy]. The main question[s] it aims to answer are: [whether the gastric is empty or not 2 hours after finishing drinking 1.5 L of MgSO4 solution within 2 hours] [whether the quality of patients' bowel preparation is superior in a time period of 2-4 hours after finishing drinking 1.5 L of MgSO4 solution] Participants will [ be asked finishing the last dose of 1.5 L MgSO4 solution within 2 hours and received ultrasound gastric assessment immediately 2 or 4 hours after finishing drinking MgSO4 solution in a 15 minutes time interval until the gastric is empty. As soon as the gastric is empty, patients receive painless colonoscopy within 2 hours or 2-4 hours. Researchers will compare [patients receiving painless colonoscopy within 2 hours or 2-4 hours after finishing drinking 1.5 L of MgSO4 solution] to see if [the quality of patients' bowel preparation is superior in a time period of within 2 hours].

NCT ID: NCT06101836 Completed - Colorectal Cancer Clinical Trials

The Impact of Remote Training on Colonoscopy KPIs

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Colonoscopy is a complex, highly operator dependent, practical skill. The consistent attainment of key performance indicators (KPIs) by endoscopists depends primarily upon training. Local factors can make training unstructured and contingent upon the observed practice of a small number of trainers. The investigators sought to demonstrate the feasibility and impact of a virtual-live one day colonoscopy-training course.

NCT ID: NCT06094270 Recruiting - Colonoscopy Clinical Trials

Artificial-intelligence-based Reporting Technology for Endoscopy Monitoring and Imaging System

ARTEMIS
Start date: December 19, 2023
Phase:
Study type: Observational

Properly documenting withdrawal time in colonoscopy is essential for quality assessment and cost allocation. However, reporting withdrawal time has significant interobserver variability. Additionally, current manual documentation of endoscopic findings is time-consuming and distracting for the physician. This trial examines an artificial intelligence based system to determine withdrawal time and create a structured report, including high-quality images (AI) of detected polyps and landmarks.

NCT ID: NCT06062030 Not yet recruiting - Colonoscopy Clinical Trials

Efficacy and Safety of DWJ1609 for Bowel Cleansing Before Colonoscopy;

Start date: November 2023
Phase: Phase 3
Study type: Interventional

Phase of Development : III Sponsor : DAEWOONG PHARMACEUTICAL Study Sites and Principal Investigator : Dong ll Park M.D. Ph.D , Gastroenterology Kangbuk Samsung Hospital and other 5 study sites Study Period : From the protocol approval date (institutional review board, IRB) 24 Months Investigational product : Investigational Products DWJ1609 (sodium sulfate potassium sulfate, Magnesium Sulfate Anhydrous , simethicone, sodium picosulphate) Control Products DWC202304 (sodium sulfate potassium sulfate, Magnesium Sulfate Anhydrous , simethicone) Target Diseases : A person who needs treatment before colonoscopy (X-ray, endoscopy) Number of Subjects : 214 Subjects in total (85 subjects per group, 2 groups in total, considering a 20% dropout rate)