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Cognitive Performance clinical trials

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NCT ID: NCT06127511 Not yet recruiting - Inflammation Clinical Trials

Peanut Consumption on Cognitive, Weight, and Inflammation

PEANUTY
Start date: January 2024
Phase: N/A
Study type: Interventional

A multi-school, two-arm parallel cluster-randomized controlled trial will be conducted in 200 healthy young adolescents from Barcelona (Spain) to evaluate the effect of peanut consumption on cognitive performance, weight management and inflammation. Schools willing to participate will be randomly assigned to either the intervention or the control group. After the recruitment, the participants will follow a peanut-free diet for two weeks. Both arms will receive a multidimensional educational intervention designed by the Gasol Foundation to promote healthy dietary habits based on Mediterranean diet recommendations, along with exercise performance, healthy sleeping habits and emotional knowledge. Half of the participants (intervention group) will consume 25 g of whole skin roasted peanuts as a daily snack to be incorporated into their diet for six months.

NCT ID: NCT05904431 Not yet recruiting - Clinical trials for Cognitive Performance

The Effect of Cognitive Performance on Physical Performance in Adolescent Basketball Players

Start date: June 30, 2023
Phase:
Study type: Observational

The aim of this study is to examine the relationship between physical fitness parameters and cognitive performance levels in basketball players. It has been shown in the literature that exercise has an effect on cognitive factors. However, there is a limited number of studies examining the relationship between physical performance parameters and cognitive performance in basketball players.

NCT ID: NCT05724654 Active, not recruiting - Clinical trials for Cognitive Performance

Effects of Peanut Consumption on Brain Function

Start date: February 8, 2023
Phase: N/A
Study type: Interventional

Impaired brain vascular function precedes the development of reduced cognitive performance, while brain insulin-resistance is also associated with cognitive decline. Peanut consumption has already been shown to beneficially affect cognitive performance. However, underlying mechanisms have not yet been established, while well-controlled trials on longer-term effects of peanuts on cognitive performance are highly needed. The hypothesis is that longer-term peanut consumption has beneficial effects on (regional) cerebral blood flow responses (primary outcome), which may relate to an improved cognitive performance (secondary outcome) in older men and women. Important objectives are to investigate in older adults the effect of 16-week peanut consumption on (i) brain vascular function in cognitive-control brain areas, and (ii) brain insulin-sensitivity. We will also focus on changes in cognitive performance as assessed with a neuropsychological test battery (secondary objective). Cerebral blood flow responses before (brain vascular function) and after the administration of intranasal insulin (brain insulin sensitivity) will be non-invasively quantified by the non-invasive gold standard magnetic resonance imaging (MRI)-perfusion method Arterial Spin Labeling (ASL).

NCT ID: NCT05653141 Recruiting - Clinical trials for Cognitive Performance

Post-stroke Cognitive Impairment

CogStroke
Start date: December 17, 2020
Phase:
Study type: Observational

Present study aims to track the post-stroke cognitive trajectories and to investigate its inter-individual variability.

NCT ID: NCT05598047 Recruiting - Aging Clinical Trials

Executive Functioning Training Study

EFT
Start date: June 13, 2023
Phase: Phase 2
Study type: Interventional

Cognitive aging in people with HIV (PWH) is of increasing concern for several reasons: 1) between 52%-59% of PWH experience cognitive impairment known as HIV-Associated Neurocognitive Disorder (HAND) which impacts everyday functioning and quality of life; 2) HAND increases in severity and prevalence with age; and 3) 70% of PWH in the United States will be 50 and older by 2030. Fortunately, cognitive training programs can individually target specific cognitive impairments in PWH and possibly reduce the severity and prevalence of HAND and improve everyday functioning and quality of life. This approach is based around the underlying concept of intra-individual variability as controlled through higher level allocation of cognitive resources, known as executive functioning. This feasibility study will use a two-group pre-post experimental design of adults with HAND including: 1) a 20-hours of Executive Functioning Training group (enroll 60, n=48 with attrition), and 2) a no-contact control (enroll 60, n=48 with attrition). Aim 1 - Feasibility: To determine feasibility and acceptability of the intervention (i.e., attrition, feedback). Exploratory Aim 1 - Cognition: Compare adults who receive Executive Functioning Training to those who receive no training to determine whether they improve in global cognitive ability and overall cognitive IIV. This high impact study is innovative in the following ways: 1) This is the first study aimed to reduce cognitive IIV in PWH. 2) This is the first study to use IIV as a guide to target solely executive functioning training to improve global cognitive ability, which may reduce the severity and prevalence of HAND. 3) Over the last decade, the epicenter of HIV has emerged in the Deep South where this study will occur. Most participants in this study will be older PWH who identify as lower social economic status (SES) and/or African Americans and experience HAND symptoms.

NCT ID: NCT05541887 Recruiting - Anxiety Clinical Trials

Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

Start date: August 30, 2023
Phase: N/A
Study type: Interventional

Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities

NCT ID: NCT05498129 Completed - Clinical trials for Cognitive Performance

School Feeding to Improve Cognitive Performance in Disadvantaged Children

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

This trial investigated the impact of providing a regular meal with and without additional multiple micronutrients for children in Northwest Pakistan on their performance at school, in comparison to a local government school that served as a control i.e. no school meal.

NCT ID: NCT05481424 Recruiting - Sleep Clinical Trials

Evaluating the Potentials of Biodynamic Lighting for Home Office Workers

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

This study examines the effectiveness of a biodynamic lighting intervention on the sleep, cognitive functions, and alertness of adults working from home. The biodynamic intervention is an innovative lighting solution that intends to harness both visual and non-visual effects of lighting through delivering varying intensities and spectra during working hours according to a preset protocol.

NCT ID: NCT05428761 Completed - Dehydration Clinical Trials

Clinical Trial to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Dehydration lowers both physical and mental performance if it is severe enough. Performance declines are more pronounced in hot conditions or after prolonged strenuous activity such as exercise. Most individuals drink less than their sweat losses during activity, while some individuals overdrink and develop a sodium deficiency. Water and electrolyte balance must be restored as part of the recovery process after any activity that causes sweating. Plain water causes a decrease in plasma sodium concentration and osmolality, which reduces the desire to drink and increases urine production. Unless the volume ingested exceeds the loss, individuals are in net negative fluid balance throughout the recovery period due to urinary losses. When sodium and potassium are added to rehydration fluids, urine production is reduced in the hours following rehydration. Rehydration is only possible if a volume of fluid equal to or greater than the amount lost through sweat is consumed, together with adequate electrolytes. The test products for this study, TP1 and TP2, are novel hydration beverage formulas. They are an electrolyte drink mixture with five essential vitamins and three times more electrolytes than typical sports beverages. The test products create an osmotic force that permits water to be supplied to the bloodstream sooner in the digestive system by using a specific ratio of sodium, glucose, and potassium. This randomized, placebo-controlled, semi-blind, crossover study will evaluate the effects of the test products on rehydration in healthy adults.

NCT ID: NCT05428228 Not yet recruiting - Dehydration Clinical Trials

Clinical Study to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The aim of the clinical trial is to evaluate the efficacy of two novel hydration products on rehydration following exercise.