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Cognitive Performance clinical trials

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NCT ID: NCT06395051 Not yet recruiting - Clinical trials for Cognitive Performance

Effects of Ketone Monoesters on Brain Function

Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Disturbances in brain insulin-sensitivity are not only observed in obesity and type 2 diabetes (T2D), but also during brain aging and in dementia. Ketone monoester supplements may improve brain insulin-sensitivity, which can be quantified by measuring the gray-matter cerebral blood flow (CBF) response to intranasally administered insulin. We hypothesize that acute ketone monoester supplementation increases (regional) brain vascular function and insulin-sensitivity thereby improving cognitive performance and appetite control. The primary objective is to evaluate in older men the acute effect of ketone monoester supplementation on (regional) brain vascular function and insulin-sensitivity, as quantified by the non-invasive gold standard magnetic resonance imaging (MRI)-perfusion method Arterial Spin Labelling (ASL). The CBF response to intranasal insulin is a robust and sensitive physiological marker of brain insulin-sensitivity. Secondary objectives are to investigate effects on cognitive performance as assessed with a neuropsychological test battery, and appetite control as quantified by functional MRI (fMRI) with visual food cues.

NCT ID: NCT06390267 Not yet recruiting - Clinical trials for Cognitive Performance

Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction

ASR
Start date: August 2024
Phase: N/A
Study type: Interventional

The objective of this study is to test the effects of transcutaneous auricular neurostimulation (tAN) in treating or preventing performance degradation after an acute stressor.

NCT ID: NCT06380582 Not yet recruiting - Clinical trials for Cognitive Performance

Indoor Air Quality, Temperature and Cognitive Performance

AEOLUS
Start date: April 25, 2024
Phase: N/A
Study type: Interventional

Study design: A cross-over single-blinded treatment design will be used. Participants will undergo 4 different conditions: (1) low air flow and 23°C, (2) low air flow and 35°C, (3) high air flow and 23°C, and (4) high air flow and 35°C. Participants will be blinded to the air quality level; however, it is not possible to blind them to the temperature condition, as they will be able to perceive it as different. Study population: The population consists of healthy young and middle-aged adults of both sexes between 18 and 40 years. Intervention (if applicable): Each participant undergoes 4 conditions in randomized order. Two conditions consist of poor air quality defined as 3,000 ppm carbon dioxide and 23°C or 35°C temperature, respectively.

NCT ID: NCT06127511 Not yet recruiting - Inflammation Clinical Trials

Peanut Consumption on Cognitive, Weight, and Inflammation

PEANUTY
Start date: January 2024
Phase: N/A
Study type: Interventional

A multi-school, two-arm parallel cluster-randomized controlled trial will be conducted in 200 healthy young adolescents from Barcelona (Spain) to evaluate the effect of peanut consumption on cognitive performance, weight management and inflammation. Schools willing to participate will be randomly assigned to either the intervention or the control group. After the recruitment, the participants will follow a peanut-free diet for two weeks. Both arms will receive a multidimensional educational intervention designed by the Gasol Foundation to promote healthy dietary habits based on Mediterranean diet recommendations, along with exercise performance, healthy sleeping habits and emotional knowledge. Half of the participants (intervention group) will consume 25 g of whole skin roasted peanuts as a daily snack to be incorporated into their diet for six months.

NCT ID: NCT05904431 Not yet recruiting - Clinical trials for Cognitive Performance

The Effect of Cognitive Performance on Physical Performance in Adolescent Basketball Players

Start date: June 30, 2023
Phase:
Study type: Observational

The aim of this study is to examine the relationship between physical fitness parameters and cognitive performance levels in basketball players. It has been shown in the literature that exercise has an effect on cognitive factors. However, there is a limited number of studies examining the relationship between physical performance parameters and cognitive performance in basketball players.

NCT ID: NCT05428228 Not yet recruiting - Dehydration Clinical Trials

Clinical Study to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The aim of the clinical trial is to evaluate the efficacy of two novel hydration products on rehydration following exercise.