Chronic Stable Coronary Artery Disease Clinical Trial
1.1 To build a TCM diagnosis and treatment database for chronic stable CAD; 1.2 To summarize
the pattern of TCM medicine used and the effect of the medication in chronic stable CAD.
1.3 To formulate a syndrome differentiation determined medicine plan based on the
improvement in the quality of life on chronic stable CAD patients.
Chronic stable coronary artery disease (SCAD) is a general term for all kinds of coronary
artery disease (CAD) which includes patients with chronic stable angina, oldmyocardial
infarctions and also stable condition after revascularization (i.e percutaneous coronary
intervention （PCI）, coronary artery bypass graft （CABG）). According to 2012 American Heart
Association/American College of Cardiology (AHA/ACC) guide, the objective of the treatment
for SCAD is to maintain or recover patients' exercise tolerance, quality of life and avoid
complication like heart failure，so as to decrease mortality, eliminate symptoms and avoid
adverse reactions.
Traditional Chinese medicine (TCM) has two thousand years of history in managing CAD and has
its advantages in improving quality of life. Using scientific method to evaluate,
demonstrate and conclude the clinical curative effect of TCM is an extremely important task
for both TCM and Chinese and western integrative medicine win the treatment of CAD. Recent
researches mainly focus on certain types or some certain pathological and physiological
stages of CAD, worse still, different areas experts have their own experiences and opinions
with the treatment. There is a lack of unified syndrome differentiation and prescriptions
plan for the chronic stable CAD and not enough attention has been paid to TCM despite it
having many advantages in improving quality of life in these patients. Considering all the
above, this research studied past syndromes research results and real clinical effective
chronic SCAD cases. Cases were analysed and explored, effective cases were filtered,
syndrome differentiation of the prescriptions was refined, thus build a TCM diagnosis and
treatment information database.
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