US-Guided SAPB Versus ESPB on Acute and Chronic Pain After VATS

Chronic Pain Clinical Trial

Official title:

Comparison of the Effects of Ultrasound-guided Serratus Anterior Plane Block and Erector Spinae Plane Block on Postoperative Acute and Chronic Pain for Patients Who Underwent Video-assisted Thoracoscopic Surgery.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05160961
• Other study ID #: E.Kurul-E1-21-2142
• Status: Recruiting
• Phase: N/A
• Start date: December 3, 2021
• Est. completion date: July 15, 2024

Study information

• Verified date: August 2023
• Source: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
• Contact: Musa Zengin, MD
• Phone: 903125677233
• Email: musazengin[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Postoperative acute and chronic pain is frequently observed in patients undergoing video assisted thoracoscopic surgery (VATS). This prolongs the discharge time of patients and increases the frequency of postoperative pulmonary complications. Recently, alternative analgesic methods such as thoracic paravertebral block (TPVB), erector spinae plane block (ESPB), and serratus anterior plane block (SAPB) which are thought to have less side effects than thoracic epidural analgesia, have been used. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In addition, ESPB and SAPB application is increasing in patients undergoing VATS. In the literature, the number of cases performed with ESPB and SAPB and randomized controlled prospective studies with ESPB and SAPB are increasing. In this study, it is planned to compare the effects of US-guided SAPB and ESPB on postoperative acute and chronic pain in patients undergoing VATS.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: July 15, 2024
• Est. primary completion date: June 15, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Age between 18 and 65 years

• American Society of Anesthesiologists physical status I-II-III

• Body mass index between 18-30 kg/m2

• Patients undergoing elective video assiste thoracoscopic surgery

Exclusion Criteria:

• Advanced cancer

• History of chronic analgesic therapy

• History of local anesthetic allergy

• Infection in the intervention area

• Patients with bleeding disorders

Related Conditions & MeSH terms

• Acute Pain
• Chronic Pain
• Erector Spinae Plane Block
• Postoperative Pain
• Serratus Anterior Plane Block
• Video-Assisted Thoracoscopic Surgery

Intervention

Procedure:
• Serratus anterior plane block
Serratus anterior plane block will be performed unilaterally, under US guidance, before the surgical operation, after the induction of anesthesia, when the patient is placed in the lateral decubitus position.
• Erector spinae plane block
Erector spinae plane block will be performed unilaterally, under US guidance, before the surgical operation, after the induction of anesthesia, when the patient is placed in the lateral decubitus position.

Locations

Country	Name	City	State
Turkey	Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital	Kecioren	Ankara

Sponsors (1)

Lead Sponsor	Collaborator
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain scores	Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th and 24th hours after surgery.	First 24 hours after surgery
Secondary	Chronic pain	Chronic pain findings will be evaluated in the 3rd month and 6th month after surgery by using visual analog from 0 (no pain) to 10 (worst pain). Neuropathic pain symptoms (Burning, stabbing, or electric shock-like pain; tingling, numbness, or a "pins and needles" feeling, hyperalgesia, allodynia and hypoesthesia) will also be asked to the participants in the 3rd month and 6th month after surgery.	3rd month and 6th month