Clinical Trials Logo

Clinical Trial Summary

The study will examine how medical cannabis use affects opioid analgesic use over time, with particular attention to THC/CBD content, HIV outcomes, and severe adverse events.


Clinical Trial Description

The overarching goal of the study is to understand how medical cannabis use affects opioid analgesic use over time, with particular attention to THC/CBD content, HIV outcomes, and adverse events. The study will include a cohort of 250 HIV+ and HIV- adults with (a) severe or chronic pain, (b) opioid analgesic use, and (c) new certification for medical cannabis. Over 18 months, participants will have 7 in-person visits every 3 months and 39 web-based questionnaires every 2 weeks. Data sources will include questionnaires; medical, pharmacy, and Prescription Monitoring Program records; and urine and blood samples. Over each 2-week time period (unit of analysis), the primary exposure measure will be number of days of medical cannabis use, and the primary outcome measure will be cumulative opioid analgesic dose. Qualitative interviews will also be conducted with a subgroup of 30 participants to explore perceptions of how medical cannabis use affects opioid analgesic use. Qualitative findings will help understand the reasons underlying the findings of the cohort study. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03268551
Study type Observational
Source Albert Einstein College of Medicine
Contact
Status Active, not recruiting
Phase
Start date September 4, 2018
Completion date June 30, 2022

See also
  Status Clinical Trial Phase
Completed NCT01659073 - Using Perfusion MRI to Measure the Dynamic Changes in Neural Activation Associated With Caloric Vestibular Stimulation N/A
Not yet recruiting NCT05422456 - The Turkish Version of Functional Disability Inventory
Not yet recruiting NCT05422443 - The Turkish Version of Pain Coping Questionnaire
Recruiting NCT05057988 - Virtual Empowered Relief for Patients With MOUD and Chronic Pain N/A
Completed NCT04385030 - Neurostimulation and Mirror Therapy in Traumatic Brachial Plexus Injury N/A
Completed NCT05103319 - Simultaneous Application of Ketamine and Lidocaine During an Ambulatory Infusion Therapy as a Treatment Option in Refractory Chronic Pain Conditions
Completed NCT03687762 - Back on Track to Healthy Living Study N/A
Completed NCT04171336 - Animal-assisted Therapy for Children and Adolescents With Chronic Pain N/A
Completed NCT03179475 - Targin® for Chronic Pain Management in Patients With Spinal Cord Injury Phase 4
Active, not recruiting NCT03418129 - Neuromodulatory Treatments for Pain Management in TBI N/A
Completed NCT00983385 - Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics Phase 3
Recruiting NCT05278533 - Evaluate the Use of the Foundation Pain Index and the Nutritional Supplement BioPleteā„¢ in Adults With Chronic Pain N/A
Completed NCT04546685 - Virtual Single-Session "Empowered Relief" Group Intervention for Chronic Pain N/A
Terminated NCT03538444 - Repetitive Transcranial Magnetic Stimulation for Opiate Use Disorder N/A
Recruiting NCT05036499 - PFI for Pain-Related Anxiety Among Hazardous Drinkers With Chronic Pain N/A
Completed NCT04010019 - The Facing Pain Study N/A
Completed NCT01939366 - Cebranopadol Efficacy and Safety in Diabetic Patients Suffering From Chronic Pain Caused by Damage to the Nerves Phase 2
Completed NCT03298269 - Behavioral Interventions for Chronic Pain and Opioid-Related Problems N/A
Recruiting NCT04567043 - Treating Opioid Misuse Via Mindfulness-Based Just-in-Time Adaptive Intervention N/A
Recruiting NCT04172272 - The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures N/A