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CBD clinical trials

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NCT ID: NCT04775030 Recruiting - Clinical trials for Temporomandibular Disorder

Methodology for Developing an Occlusal Appliance With CBD Active Carrier

CBD-OCC-APP
Start date: January 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Evaluation of the efficacy of the occlusal appliance with active cannabidiol (CBD) molecules in TMD patients

NCT ID: NCT04729244 Not yet recruiting - Anxiety Clinical Trials

The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Management

Start date: September 1, 2021
Phase: Phase 1
Study type: Interventional

The investigators are looking to conduct a study looking at the effects of cannabidiol (CBD) from Hemp Oil in patients with Chronic pain, anxiety and insomnia. It is believed that CBD will improve pain anxiety and sleep quality and reduce opioid use. The study will last a total of 4 weeks and involve onsite visits in addition to weekly pain assessments.

NCT ID: NCT04686539 Recruiting - Covid19 Clinical Trials

Synthetic CBD as a Therapy for COVID-19

Start date: January 20, 2021
Phase: Phase 1
Study type: Interventional

The study aim to test proof of concept of CBD treatment for efficacy and safety in patients suffering with mild COVID-19 infection. The CBD will be delivered via oil droplets not containing THC, compared to placebo.

NCT ID: NCT04680130 Enrolling by invitation - Parkinson Disease Clinical Trials

Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders

AND1
Start date: November 1, 2020
Phase:
Study type: Observational

The investigators aim to learn more about symptoms suggestive of a neurodegenerative process.

NCT ID: NCT04611347 Recruiting - Hand Osteoarthritis Clinical Trials

Topical CBD in Joint Arthritis

Start date: November 1, 2020
Phase: Phase 2
Study type: Interventional

Rationale: CBD is commonly being used as an over-the-counter treatment for arthritis-related pain, however no clinical trial has been performed to establish efficacy. Hypothesis: CBD is more effective than placebo for relieving pain and improving patient-reported outcomes for thumb basal joint arthritis. Study Design: The study design with be a double-blind, randomized controlled trial with crossover. Treatment will be blinded to the subjects and investigators. Patients will be randomly assigned 2 weeks of the CBD or control and then crossover to the other condition for 2 additional weeks. Patients will apply the cream at the thumb base twice daily for 1 hour. Subjects will be advised to observe for physiologic changes, skin changes, or other adverse effects.

NCT ID: NCT04527003 Recruiting - Endometriosis Clinical Trials

Cannabidiol and Management of Endometriosis Pain

Start date: December 4, 2020
Phase: Phase 3
Study type: Interventional

The investigators are looking to conduct a study looking at the effects of cannabidiol (CBD) in patients with endometriosis. It is believed that CBD will improve both pain and quality of life. The study will last a total of 12 weeks and involve several onsite visits in addition to daily pain assessments.

NCT ID: NCT04482244 Active, not recruiting - Anxiety Clinical Trials

RCT of CBD for Anxiety in Advanced Breast Cancer

Start date: January 19, 2022
Phase: Phase 2
Study type: Interventional

This research study is investigating use of a single dose of cannabidiol (CBD) to help manage anticipatory anxiety in participants with advanced breast cancer poised to undergo computed tomography (CT) or positron emission tomography (PET) to assess tumor burden. The name of the study drug(s) are: - Cannabidiol (CBD)

NCT ID: NCT04423341 Completed - Blepharospasm Clinical Trials

Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm

Start date: May 20, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The planned study is a prospective analysis of non-psychoactive Cannabidiol (without THC) as an adjunctive therapy for blepharospasm in a masked double cross-over study. This prospective study is a follow-up to a retrospective study completed by the researchers using over-the-counter, self purchased CBD. This study will use FDA approved Cannabidiol medication, Epidiolex, directly from GW pharmaceuticals, rather than self-purchased CBD from the internet. Patients will undergo videorecording with a high resolution videocamera system at days 0, 45, 90, 135, and 180 using a novel blink analysis to gather objective data measurements of changes induced by CBD in Blepharospasm patients. This study will attempt to codify the data and quantify if adjunctive CBD therapy improves those areas compared to botulinum injection alone.

NCT ID: NCT04412837 Withdrawn - Osteoarthritis Clinical Trials

The Use of Cannabinoid Patch for Knee Osteoarthritis

Start date: October 2022
Phase: Phase 2
Study type: Interventional

This randomized, double-blind 2-arm parallel group study to determine the efficacy of a cannabinoid (CBD) patch on reducing pain in patients with knee osteoarthritis.

NCT ID: NCT04398719 Recruiting - Healthy Clinical Trials

CBD-Microglia PET Study

Start date: May 7, 2021
Phase: Early Phase 1
Study type: Interventional

This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CBD) pre-treatment on central pain-sensitization in healthy human subjects.