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Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome

Cataract Clinical Trial

Official title:
Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome

Clinical Trial Summary

This study involves the collection ocular lens tissue from individuals with Down syndrome and age-matched controls at the time of cataract surgery.

Clinical Trial Description

Individuals with Down syndrome have an increased rate of cataract. The reason for this increase is unclear. Normally, once cataracts become a significant impairment, an ophthalmologist will determine when cataract surgery should be performed. When this surgery is performed, cataractous tissues are cut out and discarded with medical waste. In this study, these tissue will be collected and protein analysis performed to determine what changes in different proteins are found in Down syndrome lenses as compared to normal cataractous lenses. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03778528
Study type Observational
Source University of Colorado, Denver
Contact
Status Terminated
Phase
Start date May 30, 2018
Completion date July 1, 2020
View Details
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